Algorithm of Macrophage Activation Assessment for Forecasting and Evaluation of Treatment Effectiveness of Human Diseases

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Abstract

Despite the high complexity of macrophage activation and subsequent polarization, determination of the key dynamic features of these processes provides the basis for both assessment of macrophage activation current state and for disease prognosis. To sum it up either macrophage phenotype ratio or polarizing stimulus ratio may be the most important indicators.

About the authors

V. N. Sakharov

Sechenov First Moscow State Medical University

Author for correspondence.
Email: vladimirsah91@mail.ru
Moscow Russian Federation

P. F. Litvitskiy

Sechenov First Moscow State Medical University

Email: litvicki@mma.ru
Moscow Russian Federation

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