ABOUT THE HUMAN HEALTH SAFETY ESTIMATION OF RACTOPAMINE INTAKE TOGETHER WITH THE FOOD

Cover Page


Cite item

Full Text

Abstract

The analysis of scientific data including American and European scientific communities concerning use of ractopamine as a growth factor in food animal production and the argumentation of the maximum permitted levels of ractopamine and levels of ractopamine in meat and byproducts (offal) is carried out. The position of the Russian side stated at the Codex Alimentarius commission 35th session that acceptable ractopamine daily intake is insufficiently validated and cannot be used for the determination of maximum permitted levels of ractopamine in meat and byproducts (offal) is confirmed. It is represented that residual ractopamine intake together with food on the levels which are recommended by the Codex Alimentarius commission and by taking into account the levels of animal products consumption in Russian Federation will lead to unacceptable human health risk level that will promote increasing heart diseases and life expectancy reduction. In this connection Russia states against of acceptance of maximum permitted levels of ractopamine in food.

 

About the authors

G. G. Onishchenko

Federal service on customers' rights protection and human well-being surveillance, Moscow, Russian Federation

Author for correspondence.
Email: depart@gsen.ru
PhD, Professor, RAMS academician, Honored doctor of the Russian Federation, Head of the Federal Service for Supervision of Consumer Rights Protection and Human Well-Being Address: 127994, Moscow, Vadkovsky lane, 18, building 5, 7; tel.: (499) 973-26-90 Russian Federation

A. Yu. Popova

Federal service on customers' rights protection and human well-being surveillance, Moscow, Russian Federation

Email: depart@gsen.ru
PhD, Professor, Deputy Head of the Federal Service for Supervision of Consumer Rights Protection and Human Well-Being Address: 127994, Moscow, Vadkovsky lane, 18, building 5, 7; tel.: (499) 973-26-90 Russian Federation

V. A. Tutel'yan

Federal State Institution «Scientific-research institute of nutrition» RAMS, Moscow, Russian Federation

Email: tutelyan@ion.ru
PhD, Professor, RAMS academician, Director of the Scientific Research Institute of Nutrition RAMS Address: 109240, Moscow, Ustinskiy Proyezd 2/14; tel.: (495) 698-53-46 Russian Federation

N. V. Zaitseva

Federal Scientific Center for Medical and Preventive Health Risk Management Technologies, Perm, Russian Federation

Email: znv@fcrisk.ru
PhD, Professor, RAMS academician, Head of the Federal scientific center for medical and preventive health risk management technologies. Address: 614045, Perm, Monastyrskaya St., 82; tel.: (342) 237-25-34 Russian Federation

S. A. Khotimchenko

Federal State Institution «Scientific-research institute of nutrition» RAMS, Moscow, Russian Federation

Email: hotimchenko@ion.ru
PhD, Professor, Head of the Laboratory of Food Toxicology, Scientific Research Institute of Nutrition RAMS Address: 109240, Moscow, Ustinskiy Proyezd 2/14; tel.: (495) 698-53-68 Russian Federation

I. V. Gmoshinskii

Federal State Institution «Scientific-research institute of nutrition» RAMS, Moscow, Russian Federation

Email: gmosh@ion.ru
PhD, Leading Research Worker, Laboratory of Food Toxicology, Scientific Research Institute of Nutrition RAMS Address: 109240, Moscow, Ustinskiy Proyezd 2/14; tel.: (495) 698-53-71 Russian Federation

S. A. Sheveleva

Federal State Institution «Scientific-research institute of nutrition» RAMS, Moscow, Russian Federation

Email: sheveleva@ion.ru
PhD, Head of the Laboratory of Food Microbiology and Microecology, Scientific Research Institute of Nutrition RAMS Address: 109240, Moscow, Ustinskiy Proyezd 2/14; tel.: (495) 698-53-83 Russian Federation

V. N. Rakitskii

Federal Scientific Centre of Hygiene named after F.F. Erisman Federal service on customers' rights protection and human well-being surveillance, Moscow region, Russian Federation

Email: pesticidi@yandex.ru
Professor, RAMS academician, Director of the Institute of Hygiene, Toxicology of Pesticides and Chemical Safety, F.F.Erismana Federal Research Centre for Hygiene Address: 141000, Moscow Region, Mytishchi, Semashko St., 2; tel.: (495) 586-10-72 Russian Federation

P. Z. Shur

Federal Scientific Center for Medical and Preventive Health Risk Management Technologies, Perm, Russian Federation

Email: shur@fcrisk.ru
PhD, Scientific Secretary, Federal scientific center for medical and preventive health risk management technologies Address: 614045, Perm, Monastyrskaya St., 82; tel.: (342) 238-33-37 Russian Federation

A. B. Lisitsyn

The Gorbatov's All-Russian Meat Research Institute Russian Academy of Agricultural Science, Moscow, Russian Federation

Email: zavod@vniimp.ru
PhD, Professor, Russian Academy of Agriculture Sciences Academician, State Prize of the Russian Federation Laureate, Director of the Gorbatov's All-Russian Meat Research Institute Address: 109316, Moscow, Talalikhina St., 26; tel.: (495) 676-63-51 Russian Federation

D. A. Kir'yanov

Federal Scientific Center for Medical and Preventive Health Risk Management Technologies, Perm, Russian Federation

Email: kda@fcrisk.ru
PhD, Head of the Department of Mathematical Modeling of Systems and Processes, Federal scientific center for medical and preventive health risk management technologies Address: 614045, Perm, Monastyrskaya St., 82; tel.: (342) 237-18-04, (950) 47-109-02 Russian Federation

References

  1. Codex Alimentarius Commission adopts maximum residue levels. UN food safety body sets limits on veterinary growth promoting drug 06–07–2012. Available at: http://www.fao.org/news/story/en/item/150953/icode/
  2. Joint FAO/WHO Food Standard Programme Codex Alimentarius Commission. Thirty-fifth Session FAO Headquarters, RJEP12/CAC. Rome, Italy. 2–7 July 2012. p. 87–120.
  3. Residue evaluation of certain veterinary drugs. Meeting 2010 — Evaluation of data on ractopamine residues in pig tissues. Joint FAO/WHO Expert Committee on Food Additives. Rome, Italy. 2010. 52 p.
  4. Scientific Opinion of the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) on a request from the European Commission on the safety evaluation of ractopamine. EFSA J. 2009; 1041: l–52.
  5. Council Directive 96/22/EC of 29 April 1996 concerning on the use in stockfarming of certain substances having a hormonal or thyrostatic action and of beta-agonists, and repealing Directives 81/602/EEC, 88/146/EEC and 88/299/EEC. Official J. Eur. Communities. L125, 23.5.1996, p.3.
  6. Alemanno A., Capodieci G. Testing the Limits of Global Food Governance: The Case of Ractopamine. Eur. J. Risk Regul. 2012; 3: 12.
  7. Evaluation of certain veterinary drug residues in food //Joint FAO/WHO Expert Committee on Food Additives. WHO technical report series. 925. Rome, Italy. 2004. Р. 37–49.
  8. MacNeil J.D., Saskatoon, Soback S. Ractopamine Hydrochloride. Supersedes the monograph prepared by the 40th Meeting of the Committee and published in FAO Food & Nutrition Paper 41/5. FAO FNP 41/16. P. 75–92. Available at: http://www.fao.org/ag/agn/jecfa-vetdrugs/details.html?substance=3 86
  9. Available at: http://www.inchem.org/documents/jecfa/jecmono/v53je08.htm //WHO Food additives series: 53. Ractopamine (addendum) /First draft prepared by Professor F.R.Ungemach. Institute of Pharmacology, Pharmacy and Toxicology Veterinary Faculty, University of Leipzig. Leipzig, Germany
  10. Toxicological evaluation of certain veterinary drug residues in food/prepared by the sixty-second meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). (WHO food additives series ; 53). ISBN 92 4 166053 8 (NLM classification: WA 712) ISSN 0300-0923.-© World Health Organization 2004. р.119-164 (Available at:http://whqlibdoc.who.int/publications/2004/9241660538_ractopamine.pdf)
  11. Azbel M.Y. Proc. Natl. Acad. Sci. USA. 1994; 91: 12453—12457.
  12. Levine H.J. J. Amer. Coll. Cardiol. 1997; 30: 1104—1106.
  13. Ritter L. Ractopamine. WHO Food additives series. Available at: http:// www. inchem. org/documents/jecfa/
  14. Food & Drug Administration (1999). Ractopamine hydrochloride.
  15. A Chronic Toxicity Study of Ractopamine Hydrochloride Administered Orally to Beagle Dogs for One Year. Study D05885. June, 1987.
  16. Trusov P.V., Zaitseva N.V., Kir'yanov D.A., Kamaltdinov M.R., Tsinker M.Yu., Chigvintsev V.M., Lanin D.V. The mathematical model of the evolution of functional disorders in the human body, taking into account environmental factors. Matematicheskoe modelirovanie i bioinformatika – Mathematical modeling and bioinformatics. 2012; 2: 589–610. Available at: http://www.matbio.org/2012/Trusov_7_589.pdf (accessed: 05.12.2012).
  17. Kolichestvennaya otsenka nekantserogennogo riska pri vozdeistvii khimicheskikh veshchestv na osnove postroeniya evolyutsionnykh modelei. Metod. rekomend [Quantitative Evaluation of Carcinogenic Risks of Exposure to Chemicals on the Basis of the Construction of Evolutionary Models. Methodological Recommended.]. Moscow, Federal'nyi tsentr gigieny i epidemiologii Rospotrebnadzora, 2012. 36 p.
  18. Elanco report and DO 4686, Р03086, and АВС-0330.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 1970 "Paediatrician" Publishers LLC



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies