ETIOLOGICAL STRUCTURE OF ACUTE RESPIRATORY VIRAL INFECTIONS MORBIDITY IN NOVOSIBIRSK AND NOVOSIBIRSK REGION IN EPIDEMIC SEASON 2011–2012

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Abstract

Introduction. ARI occupying the first place in the structure of total human morbidity. The aim of the study was to investigate the species diversity of the viruses causing ARI among residents of the Novosibirsk region during epidemic season (October to April). Materials and methods. 164 nasopharyngeal swabs were collected and analyzed. Viral RNA/DNA, cDNA synthesis and PCR were carried out employing “RIBO-prep”, “Reverta-L”, “AmpliSens Influenza virus A/B-FL” and “AmpliSens ARI-screen-FL” kits (CRI of Epidemiology). Results. Etiological agent of the disease was found in 69 (43%) samples. Monoinfection was found in 58 (35%).In 14 (9%) samples were detected serogroup I coronaviruses, in 13 (8%) rhinoviruses, in 7 (4%) respiratory syncytial virus, in 6 (4%) parainfluenza virus type 1, in 5 (3%) parainfluenza virus type 3. Adenoviruses and bocavirus were identified in 3 (2%) samples. Parainfluenza virus type 2 and 4, metapneumovirus, serogroup II coronaviruses (HKU1 and OC43) were presented in 2 (1%) samples. In 11 (7%) samples was found mixed infection. Conclusion. The majority of common colds were caused by serogroup I coronaviruses (NL63 and 229E), rhinoviruses and mixed infections. The peak of species variability of viruses caused acute respiratory infections was determined in age group of children 2–4 years old. In older age groups the species variability of analyzed viruses was decreased, rhinovirus infection becomes prevalent.

 

About the authors

E. I. Sergeeva

State Research Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk Region, Russian Federation

Author for correspondence.
Email: esergeeva@vector.nsc.ru
Junior Research Worker, Department Collection of Microorganisms, State Research Center of Virology and Biotechnology (VECTOR) Address: 630559, Novosibirsk region, Novosibirsk district, Koltsovo work settlement, 12; tel.: (923) 239-58-22 Россия

E. V. Ivanova

Center of Hygiene and Epidemiology in Novosibirsk Region, Novosibirsk, Russian Federation

Email: Virusolog@cn.ru
Head of Virology Laboratory, Centre of Hygiene and Epidemiology in the Novosibirsk Region Address: 630099, Moscow, Frunze St., 84; tel.: (383) 224-26-52 Россия

A. N. Shvalov

State Research Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk Region, Russian Federation

Email: shvalov@mail.ru
PhD, Research Worker, Department of Molecular Virology of Flavivirus and Viral Hepatitis, State Research Center of Virology and Biotechnology (VECTOR) Address: 630559, Novosibirsk region, Novosibirsk district, Koltsovo work settlement, 12; tel.: (383) 363-47-60 Россия

V. A. Ternovoi

State Research Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk Region, Russian Federation

Email: tern@vector.nsc.ru
PhD, Head of the Laboratory of Molecular Epidemiology of especially dangerous infections, State Research Center of Virology and Biotechnology (VECTOR) Address: 630559, Novosibirsk region, Novosibirsk district, Koltsovo work settlement, 12; tel.: (383) 363-48-25 Россия

V. N. Mikheev

State Research Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk Region, Russian Federation

Email: vn_mikheev@vector.nsc.ru
Deputy Director General for Research and epidemiological work, State Research Center of Virology and Biotechnology (VECTOR) Address: 630559, Novosibirsk region, Novosibirsk district, Koltsovo work settlement, 12; tel.: (383) 336-73-27 Россия

A. P. Agafonov

State Research Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk Region, Russian Federation

Email: agafonov@vector.nsc.ru
Deputy Director General for Research, State Research Center of Virology and Biotechnology (VECTOR) Address: 630559, Novosibirsk region, Novosibirsk district, Koltsovo work settlement, 12; tel.: (383) 306-15-12 Россия

L. K. Ivanova

Center of Hygiene and Epidemiology in Novosibirsk Region, Novosibirsk, Russian Federation

Email: cgnso@cn.ru
Head Physician of the Center for Hygiene and Epidemiology in the Novosibirsk region Address: 630099, Moscow, Frunze St., 84; tel.: (383)224-24-52 Россия

A. N. Sergeev

State Research Center of Virology and Biotechnology «Vector», Koltsovo, Novosibirsk Region, Russian Federation

Email: esergeeva@vector.nsc.ru
Director General of State Research Center of Virology and Biotechnology (VECTOR) Address: 630559, Novosibirsk region, Novosibirsk district, Koltsovo work settlement, 12; tel.: (383) 336-60-10 Россия

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