Features of Urine Biomineralization in Long-Livers

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Abstract


The increasing number of long-livers in the developed countries indicates the demand for clarification of the body vital systems’ functioning features which allow the long-livers to prolong their active involvement in social life.

Objective: Aim of our study/research was to define a functional condition of urinary system in long-livers using the new diagnostic technology which analyses the structures of biological liquid at its phase transition in a solid state.

Methods: A case series study was held. All long-livers suffered from atherosclerosis and its complications as well as from associated diseases. An exclusion criterion was acute conditions. The creatinine level in blood serum, indicators of common urine analysis and features of urine facies (using cuneiform dehydration) were defined.

Results: Participants included 60 long-livers (mean age 87.34±4.17 years) who were passing clinical laboratory tests at in-patient department of gerontological hospital. In urine facies of 41 (68.3%) long-livers a phenomenon of salt crystals distribution was identified. It presents the concentration of anisotropic salt crystals in the form of a ring in a regional facies zone. The tenfold increase in concentration of calcium and double increase in concentration of phosphorus in comparison with the central zone was detected in long-livers with a higher percent sulphur in the regional zone of urine facies.

Conclusion: The urine facies of the majority of long-livers have signs of age structure formation associated with a specific distribution of anisotropic salt crystals which fix detritus in its inert form to block the autointoxication.


V. N. Shabalin1

Institute of the General Pathology and Pathophysiology, Russian Academy of Sciences

Author for correspondence.
Email: niiopp@mail.ru

Russian Federation Moscow

D. S. Uvarova

Institute of the General Pathology and Pathophysiology, Russian Academy of Sciences

Email: niiopp@mail.ru

Russian Federation Moscow

I. S. Shatokhina

M.F. Vladimirskiy Moscow Regional Research and Clinical Institute

Email: moniki@monikiweb.ru

Russian Federation Moscow

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