HISTOMORPHOMETRIC AND QUANTITATIVE HISTOCHEMICAL ANALYSIS OF PERIIMPLANTATION ZONE IN PATIENTS WITH DIFFERENT BONE MINERAL DENSITY WITHIN DENTAL IMPLANTATION

Cover Page

Abstract


Background: The aim of the work is to study histomorphometric and histochemical properties of jaw bone loss in patients with full or partial edentulism, need to restoring their dentition integrity by dental implantation. Patients and methods: Cytological studies were carried out in 83 patients, among which normal bone mass was observed in 28 patients (17 women and 11 men), osteopenia in 26 patients (17 women and 9 men), osteoporosis in 29 (19 women and 10 men) patients. Histological examination of bone biopsies were performed in 76 patients, among which normal bone mass was observed in 22 (16 women and 6 men , osteopenia in 26 patients (17 women and 9 men), osteoporosis in 28 (19 women and 9 men) patients. Results: Histomorphometric analysis of «implant–bone» contact in the entire length of the joint in patients with normal bone mass was 61,8±3,7%, with osteopenia was 51,6±3,0%, with osteoporosis was 46,1±2,8%. The intensity of bone remodeling in patients with normal bone mass was 2,7±0,19, in patients with osteopenia was 2,2±0,14, in patients with osteoporosis was 1,8±0,11. This demonstrates the significant difference between the patients with normal bone mass and osteoporotic patients. The «implant–bone» interface in osteoporotic patients was significantly lower than in patients with normal bone mass. Conclusion: Histomorphometric studies and quantitative histochemical analysis revealed that the decrease of bone mineral mass in patients often combined with a decrease of the «implant surface–bone» site contact area, with atrophy and with hypoplasia of perimplant tissues.


About the authors

A. R. Aghazadeh

A. Aliyev Azerbaijan State Advanced Training Institute for Doctors, Baku, Republic of Azerbaijan

Author for correspondence.
Email: afa-aghazada@rambler.ru

Azerbaijan

доцент кафедры стоматологии и челюстно-лицевой хирургии Азербайджанского государственного института усовершенствования врачей им. А. Алиева
Адрес: AZ1012, Баку, Тбилисский пр-т, д. 3165, тел.: (994) 50 325-63-62

I. A. Hasanov

A. Aliyev Azerbaijan State Advanced Training Institute for Doctors, Baku, Republic of Azerbaijan

Email: ih12061024@rambler.ru

Azerbaijan

доктор медицинских наук, профессор, врач-патологоанатом лаборатории патологии Центрального таможенного госпиталя
Адрес: AZ1065, Баку, ул. К. Казимзаде, д. 118, тел.: (994) 50 375-49-35

R. R. Aghazadeh

A. Aliyev Azerbaijan State Advanced Training Institute for Doctors, Baku, Republic of Azerbaijan

Email: rustam248@hotmail.com

Azerbaijan

резидент кафедры стоматологии и челюстно-лицевой хирургии Азербайджанского государственного института усовершенствования врачей им. А. Алиева
Адрес: AZ1012, Баку, Тбилисский пр-т, д. 3165, тел.: (055) 620-60-37

References

  1. Поворознюк В.В., Мазур И.П. Остеопороз и заболевания пародонта. Пародонтология. 2005; 3 (36): 14–19.
  2. Edwards B.J., Migliorati C.A. Osteoporosis and its implications for dental patients. J. Am. Dent. Assoc. 2008; 139 (5): 545–552.
  3. Narayanan V.S., Ashok L. Osteoporosis: Dental implication. J. Indian Acad. Oral Med. & Radiol. 2011; 23 (3): 211–215.
  4. Stewart S., Hanning R. Building osteoporosis prevention into dental practice. J. Can. Dent. Assos. 2012; 78: 29.
  5. Becker W., Hujoel P., Becker B., Willingham H. Osteoporosis and implant failure: an exploratory case-control study. J. Periodontol. 2000; 71: 625–631.
  6. Becker A.R., Handick K.E., Roberts W.E., Garetto L.P. Osteoporosis risk factors in female dental patients. A preliminary report. J. Indian Dent. Assoc. 1997; 76 (2): 15–19.
  7. Roberts W.E., Simmons K.E., Garetto L.P., DeCastro R.A. Bone physiology and metabolism in dental implantology: risk factors for osteoporosis and other metabolic bone diseases. Implant. Dent. 1992; 1 (1): 11–21.
  8. Дедов И.И., Марова Е.И., Рожинская Л.Я. Остеопороз: патогенез, диагностика, принципы профилактики и лечения. Метод. пос. для врачей. М. 1999. 62 с.
  9. Shibli J.A., Aguiar K.C., Melo L., d’Avila S., Zenobio E.G., Faveri M., Iezzi G., Piattelli A. Histological comparison between implants retrieved from patients with and without osteoporosis. Int. J. Oral Maxillofac. Surg. 2008; 37 (4): 321–327.
  10. Todisco M., Trisi P. Bone mineral density and bone histomorphometry are statistically related. Int. J. Oral Maxillofac. Implants. 2005; 20 (6): 898–904.
  11. Kiernan J.A. Histological and Histochemical Methods: Theory and Practice. 4 edn Cold Spring Harbor Laboratory Press. 606 p.
  12. Mark R. Wick. Diagnostic histochemistry. Cambridge. 2008. 472 p.
  13. Yu ehuei H.An., Kylie L. Martin Handbook of Histology Methods for Bone and Cartilage. New York. Springer-Verlag, 2003. 587 p.
  14. Crowder C., Stout S. Bone Histology: An Anthropological Perspective. Danvers: CRC Press. 2011. 417 p.
  15. Кактурский Л.В. Корреляционный анализ таблиц сопряженности. Арх. патол. 1980; 42 (3): 78–80.
  16. Юнкеров В.И., Григорьев С.Г., Резванцев М.В. Математико-статистическая обработка данных медицинских исследований. СПб.: ВмедА. 2011. 318 с.

Statistics

Views

Abstract - 241

PDF (Russian) - 204

Cited-By


PlumX

Dimensions



Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies