DEPRESSION AND CARDIOVASCULAR DISEASES

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Abstract


Depression is considered to be an independent cardiovascular risk factor and it may worsen the symptoms of already established cardiovascular pathology such as coronary heart disease, chronic heart failure, stroke and hypertension. 3 key psychobiological mechanisms by means of which depression influences cardiovascular system: disbalance in stress response of endocrine system, hyperregulation of autonomic nervous system and immune disorders leading to dysregulation of acute phase proteins and proinflammatory cytokines release. In majority of studies in patients with depression and cardiovascular diseases it was shown that antidepressants improve the symptoms. By the way, in some studies controversial results were obtained. Future studies in this direction with involvement of cardiologists and psychiatrists should be held.

 


N. F. Nuralieva

I.M. Sechenov First Moscow State Medical University, Russian Federation

Author for correspondence.
Email: NNurana@yandex.ru

Russian Federation undergraduate of Faculty of general medicine of I.M. Sechenov First Moscow State Medical University Address: bld. 2, 8, Trubetskaya Street, Moscow, 119992, tel.: +7 (495) 609-14-00

D. A. Napalkov

I.M. Sechenov First Moscow State Medical University, Russian Federation

Email: dminap@mail.ru

Russian Federation

PhD, professor of the Intermediate Level Therapy Department of №1 of Faculty of general medicine of I.M. Sechenov First Moscow State Medical University, Head of the Therapy School of I.M. Sechenov First MSMU Address: bld. 2, 8, Trubetskaya Street, Moscow, 119992, tel.: +7 (495) 609-14-00

  1. Depression and high school students. Bethesda: National Institute of Mental Health. 2012. P. 4. URL: http://www.nimh.nih.gov/ health/publications/depression-and-high-school-students/index. shtml (available: 22.05.2014).
  2. Depression and stroke. Bethesda: National Institute of Mental Health. 2011. P. 9. URL: http://www.a2zpsychology.com/resources/nimh/ Depression%20and%20Stroke.pdf (available: 22.05.2014).
  3. Meng L., Chen D., Yang Y., Zheng Y., Hui R. Depression increases the risk of hypertension incidence: a meta-analysis of prospective cohort studies. J. Hypertens. 2012; 30 (5): 842–851.
  4. Voinov B., Richie W.D., Bailey R.K. Depression and chronic diseases: it is time for a synergistic mental health and primary care approach. Prim. Care Companion CNS Disord. 2013; 15 (2). URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733529/ (available: 28.05.2014).
  5. Huang C.Q., Dong B.R., Lu Z.C., Yue J.R., Liu Q.X. Chronic diseases and risk for depression in old age: a meta-analysis of published literature. Ageing. Res. Rev. 2010; 9 (2): 131–141.
  6. Dong J.Y., Zhang Y.H., Tong J. Depression and risk of stroke: a meta-analysis of prospective studies. Stroke. 2012; 43: 32–37.
  7. Jackson C.A., Mishra G.D. Depression and risk of stroke in midaged women: a prospective longitudinal study. Stroke. 2013; 44 (6): 1555–1560.
  8. Pan A., Okereke O.I., Sun Q., Logroscino G., Manson J.E., Willett W.C., Ascherio A., Hu F.B., Rexrode K.M. Depression and incident stroke in women. Stroke. 2011; 42 (10): 2770–2775.
  9. Colotto M., Rubini G., Savoriti C., D’Adduogo N., Mercuri S. Impact of depression syndrome in the management of cardiovascular risk factors in primary prevention: State of the art. Clin. Ter. 2010; 161 (3): 105–110.
  10. Van der Kooy K., van Hout H., Marwijk H., Marten H., Stehouwer C., Beekman A. Depression and the risk for cardiovascular diseases: systematic review and meta analysis. Int. J. Geriatr. Psychiatry. 2007; 22 (7): 613–626.
  11. Goldston K., Baillie A.J. Depression and coronary heart disease: a review of the epidemiological evidence, explanatory mechanisms and management approaches. Clin. Psychol. Rev. 2008; 28 (2): 288–306.
  12. Michal M., Wiltink J., Lackner K., Wild P.S. Zwiener I., Blettner M., Münzel T., Schulz A., Kirschner Y., Beutel M.E. Association of hypertension with depression in the community: results from the Gutenberg Health Study. J. Hypert. 2013; 3 (5): 893–899.
  13. Doyle F., Rohde D., Rutkowska A., Morgan K., Cousins G., McGee H. Systematic review and meta-analysis of the impact of depression on subsequent smoking cessation in patients with coronary heart disease: 1990 to 2013. Psychosom. Med. 2014; 76 (1): 44–57.
  14. Eze-Nliam C.M., Thombs B.D., Limad B.B., Smith C.G., Ziegel-stein R.C. The association of depression with adherence to antihypertensive medications: a systematic review. J. Hypert. 2010; 28 (9): 1785–1795.
  15. Dickens C., Cherrington A., McGowan L. Depression and health-related quality of life in people with coronary heart disease: a systematic review. Eur. J. Cardiovasc. Nurs. 2012; 11 (3): 265–275.
  16. Mols F., Martens E.J., Denollet J. Type D personality and depressive symptoms are independent predictors of impaired health status following acute myocardial infarction. Heart. 2010; 96 (1): 30–35.
  17. Oganov R.G., Pogosova G.V., Koltunov I.E., Romasenko D.V., Deev A.D. Yufereva Yu.M. Depressive symptoms worsen cardiovascular prognosis and shorten length of life in patients with arterial hypertension and ischemic heart disease. Kardiologiya. 2011; 51 (2): 59–66.
  18. Lichtman J.H., Froelicher E.S., Blumenthal J.A., Carney R.M., Doering L.V., Frasure-Smith N., Freedland K.E., Jaffe A.S., Leifheit-Limson E.C., Sheps D.S., Vaccarino V., Wulsin L. Depression as a risk factor for poor prognosis among patients with acute coronary syndrome: systematic review and recommendations: a scientific statement from the American Heart Association. Circulation. 2014; 129 (12): 1350–1369.
  19. Kaptein K.I., de Jonge P., van den Brink R.Н., Korf J. Course of depressive symptoms after myocardial infarction and cardiac prognosis: a latent class analysis. Psych. Med. 2006; 68 (5): 662–668.
  20. Parashar S., Rumsfeld J.S., Spertus J.A., Reid K.J., Wenger N.K., Krumholz H.M., Amin A., Weintraub W.S., Lichtman J., Dawood N., Vaccarino V. Time course of depression and outcome of myocardial infarction. Arch. Int. Med. 2006; 166 (18): 2035–2043.
  21. O’Neil A., Sanderson K., Oldenburg B. Depression as a predictor of work resumption following myocardial infarction (MI): a review of recent research evidence. Health and Quality of Life Outcomes. 2010; 8: 95.
  22. Meijer A., Conradi H.J., Bos E.H., Anselmino M., Carney R.M., Denollet J., Doyle F., Freedland K.E., Grace S.L., Hosseini S.H., Lane D.A., Pilote L., Parakh K., Rafanelli C., Sato H., Steeds R.P., Welin C., de Jonge P. Adjusted prognostic association of depression following myocardial infarction with mortality and cardiovascular events: individual patient data meta-analysis. Brit. J. Psychiatry. 2013; 203 (2): 90–102.
  23. Aben I., Verhey F., Strik J., Lousberg R., Lodder J., Honig A.A. comparative study into the one year cumulative incidence of depression after stroke and myocardial infarction. J. Neurol., Neurosurgery & Psychiatry. 2003; 74 (5): 581–585.
  24. Hornsten C., Lövheim H., Gustafson Y. The association between stroke, depression, and 5-year mortality among very old people. Stroke. 2013; 44 (9): 2587–2589.
  25. Makaya M., Matsuoka S., Kato N. Combination of depression and poor knowledge regarding heart failure: a strong determinant of self-care behavior in patients with heart failure. Eur. Heart J. 2013; 34 (1): 5130.
  26. MacKenzie M.A., Buck H.G., Riegel B. «I need a nap»: excessive daytime sleepiness impacts how age and depression are associated in heart failure. Circulation. 2010; 122: 12367.
  27. Eastwood J.A., Doering L.V., Lennie T.A., Mudd-Martin G., Biddle M.J., Moser D.K. Anxiety, depression and age: implications for women with heart failure. Circulation. 2013; 128: 16258.
  28. Frasure-Smith N., Lespérance F., Habra M., Talajic M., Khairy P., Dorian P., Roy D. Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure. Circulation. 2009; 120 (2): 134–140.
  29. Драпкина О.М., Дадаева В.А. Влияние депрессии на качество жизни у больных с хронической сердечной недостаточностью. Сеченовский вестник. 2014; 2 (16): 41–44.
  30. Moraska A.R., Chamberlain A.M., Shah N.D., Vickers K.S., Rum-mans T.A., Dunlay S.M., Spertus J.A., Weston S.A., McNallan S.M., Redfield M.M., Roger V.L. Depression, healthcare utilization, and death in heart failure: a community study. Circulation: Heart Failure. 2013; 6 (3): 387–394.
  31. Jiang W., Kuchibhatla M., Cuffe M.S. Christopher E.J., Alexander J.D., Clary G.L., Blazing M.A., Gaulden L.H., Califf R.M., Krishnan R.R., O’Connor C.M. Prognostic value of anxiety and depression in patients with chronic heart failure. Circulation. 2004; 110 (22): 3452–3456.
  32. Hwang B., Moser D.K., Pelter M.M., Dracup К. Worsening somatic depressive symptoms are associated with increased mortality in patients with heart failure. Circulation. 2013; 128: 15988.
  33. Hamer M., Batty G.D., Stamatakis E. Hypertension awareness and psychological distress. Hypertension. 2010; 56 (3): 547–550.
  34. Ladwig K.H., Emeny R.T., Häfner S., Lacruz M.E. Depression. An underestimated risk for the development and progression of coronary heart disease. Bundesgesundheitsblatt Gesundheitsforsc-hung Gesundheitsschutz. 2011; 54 (1): 59–65.
  35. Fosbol E.L., Gislason G.H., Poulsen H.E., Hansen M.L., Folke F., Schramm T.K., Olesen J.B., Bretler D.M., Abildstrom S.Z., Sorensen R., Hvelplund A., Kober L., Torp-Pedersen C. Prognosis in heart failure and the value of beta-blockers are altered by the use of antidepressants and depend on the type of antidepressants used. Circulation: Heart Failure. 2009; 2 (6): 582–590.
  36. Plante G.E. Depression and cardiovascular disease: a reciprocal relationship. Metabolism. 2005; 54 (5 Suppl. 1): 45–48.
  37. Ziegelstein R.C., Parakh K., Sakhuja A., Bhat U. Platelet function in patients with major depression. Int. Med. J. 2008; 39 (1): 38–43.
  38. Kim J.H., Kim J.W., Ko Y.H., Choi C.U., Na J.O., Kim E.J., Rha S.W., Park C.G., Seo H.S., Oh D.J. Coronary endothelial dysfunction associated with a depressive mood in patients with atypical angina but angiographically normal coronary artery. Int. J. Cardiol. 2010; 143 (2): 154–157.
  39. Serebruany V.L., Glassman A.H., Malinin A.I., Nemeroff C.B., Musselman D.L., van Zyl L.T., Finkel M.S., Krishnan K.R., Gaffney M., Harrison W., Califf R.M., O’Connor C.M. Platelet/ endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudу. Circulation. 2003; 108 (8): 939–944.
  40. Sauer W.H., Berlin J.A., Kimmel S.E. Effect of antidepressants and their relative affinity for the serotonin transporter on the risk of myocardial infarction. Circulation. 2003; 108 (1): 32–36.
  41. Su S., Zhao J., Bremner J.D., Miller A.H., Tang W., Bouzyk M., Snieder H., Novik O., Afzal N., Goldberg J., Vaccarino V. Serotonin transporter gene, depressive symptoms, and interleukin-6. Circ. Cardiovasc. Genet. 2009; 2 (6): 614–620.
  42. Sorensenf C., Friis-Hasché E., Haghfelt T., Bech P. Postmyocar-dial infarction mortality in relation to depression: a systematic critical review. Psychother. Psychosom. 2005; 74 (2): 69–80.
  43. Diminic I., Franciskovic T., Ivosević D., Dusević J. The outcome of treatment with antidepressants in patients with hypertension and unrecognised depression. Eur. Psychiatry. 2008; 23 (Suppl. 2): 248–249.
  44. Bogner H.R., de Vries H.F. Integration of Depression and Hypertension treatment: a pilot Randomized Controlled Trial. Ann. Family Med. 2008; 6 (4): 295–301.
  45. Ramadan R., Sheps D., Esteves F., Raggi Р., Kutner M.H., Bremner D., Quyyumi A., Vaccarino V. Antidepressant use is associated with reduced cardiovascular reactivity and myocardial ischemia during mental stress. Circulation. 2013; 128: 12231.
  46. Майский В.В. Элементарная фармакология. М.: ГЭОТАР-Медиа. 2009. 543 с.
  47. Lin J.W., Chang C.H., Lin C.H. Effects of selective serotonin reup-take inhibitors versus tricyclic antidepressants on cerebrovascular events. Stroke. 2013; 44: 167.
  48. Tata L.J., West J., Smith C., Farrington P., Card T., Smeeth L., Hubbard R. General population based study of the impact of tri-cyclic and selective serotonin reuptake inhibitor antidepressants on the risk of acute myocardial infarction. Heart. 2005; 91 (4): 465–471.
  49. Jiang W., Kuchibhatla M., Clary G.L. Depression, antidepressants, and prognosis of patients with heart failure. Circulation. 2006; 114: 528–529.
  50. Hackett M.L., Anderson C.S., House A.O. Management of depression after stroke: a systematic review of pharmacological therapies. Stroke. 2005; 36 (5): 1098–1103.
  51. Basimovich O.Y. Influence of some antidepressants from group of the selective inhibitors of recapture of the serotonin and the extract of common St. John’s Wort (Hypericum Perforatum) on the psychologıcal status of the patients with arterial hypertension. J. Am. Coll. Cardiol. 2013; 62 (18): 95.

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