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Вестник Российской академии медицинских наук

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ДЕПРЕССИЯ И СЕРДЕЧНО-СОСУДИСТЫЕ ЗАБОЛЕВАНИЯ

https://doi.org/10.15690/vramn384

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Аннотация

Депрессия представляет собой независимый фактор риска развития сердечно-сосудистых заболеваний, а также ухудшает течение уже имеющейся кардиологической патологии: ишемической болезни сердца, хронической сердечной недостаточности, перенесенного инсульта, артериальной гипертензии. Определены три основных психобиологических механизма, посредством которых депрессия влияет на сердечно-сосудистую систему: нарушение стрессового ответа эндокринной системы; гиперрегуляция автономной нервной системы и нарушения в иммунной системе с дисрегуляцией высвобождения белков острой фазы и провоспалительных цитокинов. В большинстве исследований у пациентов с депрессией и сердечно-сосудистыми заболеваниями показано, что лечение антидепрессантами приводит к улучшению симптоматики. В то же время в ряде исследований продемонстрирована обратная закономерность, ввиду чего необходимо дальнейшие проведение исследований в данном направлении с участием клиницистов-кардиологов и психиатров.

 

Об авторах

Н. Ф. Нуралиева
Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация
Россия
студентка 6-го курса лечебного факультета Первого МГМУ им. И.М. Сеченова Адрес: 119992, Москва, ул. Трубецкая, д. 8, стр. 2, тел.: +7 (495) 609-14-00


Д. А. Напалков
Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация
Россия
доктор медицинских наук, профессор кафедры факультетской терапии №1 лечебного факультета Первого МГМУ им. И.М. Сеченова, руководитель Школы мастерства по терапии Первого МГМУ им. И.М. Сеченова Адрес: 119992, Москва, ул. Трубецкая, д. 8, стр. 2, тел.: +7 (495) 609-14-00

 



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Для цитирования:


Нуралиева Н.Ф., Напалков Д.А. ДЕПРЕССИЯ И СЕРДЕЧНО-СОСУДИСТЫЕ ЗАБОЛЕВАНИЯ. Вестник Российской академии медицинских наук. 2014;69(9-10):21-26. https://doi.org/10.15690/vramn384

For citation:


Nuralieva N.F., Napalkov D.A. DEPRESSION AND CARDIOVASCULAR DISEASES. Annals of the Russian academy of medical sciences. 2014;69(9-10):21-26. (In Russ.) https://doi.org/10.15690/vramn384

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