ДЕПРЕССИЯ И СЕРДЕЧНО-СОСУДИСТЫЕ ЗАБОЛЕВАНИЯ

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Аннотация

Депрессия представляет собой независимый фактор риска развития сердечно-сосудистых заболеваний, а также ухудшает течение уже имеющейся кардиологической патологии: ишемической болезни сердца, хронической сердечной недостаточности, перенесенного инсульта, артериальной гипертензии. Определены три основных психобиологических механизма, посредством которых депрессия влияет на сердечно-сосудистую систему: нарушение стрессового ответа эндокринной системы; гиперрегуляция автономной нервной системы и нарушения в иммунной системе с дисрегуляцией высвобождения белков острой фазы и провоспалительных цитокинов. В большинстве исследований у пациентов с депрессией и сердечно-сосудистыми заболеваниями показано, что лечение антидепрессантами приводит к улучшению симптоматики. В то же время в ряде исследований продемонстрирована обратная закономерность, ввиду чего необходимо дальнейшие проведение исследований в данном направлении с участием клиницистов-кардиологов и психиатров.

 

Об авторах

Н. Ф. Нуралиева

Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация

Автор, ответственный за переписку.
Email: NNurana@yandex.ru
студентка 6-го курса лечебного факультета Первого МГМУ им. И.М. Сеченова Адрес: 119992, Москва, ул. Трубецкая, д. 8, стр. 2, тел.: +7 (495) 609-14-00 Россия

Д. А. Напалков

Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация

Email: dminap@mail.ru
доктор медицинских наук, профессор кафедры факультетской терапии №1 лечебного факультета Первого МГМУ им. И.М. Сеченова, руководитель Школы мастерства по терапии Первого МГМУ им. И.М. Сеченова Адрес: 119992, Москва, ул. Трубецкая, д. 8, стр. 2, тел.: +7 (495) 609-14-00

 

Россия

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