MODERN WAYS OF TREATMENT OF THE INFECTION THE BOTTOM DEPARTMENT OF SEXUAL WAYS OF WOMEN

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Abstract


In article various ways of increase of efficiency of treatment of is mixed the bacterial-virus infection of the bottom department of sexual ways at women by means of application in complex therapy of homologous bacteriophages, pectovit, antiviral –immunomodulation therapies and sated with oxygen (oxygenic) water solutions of antiseptic tanks are considered. The scientifically-practical urgency of this problem is represented and actual for the decision of an important social and economic problem of improvement of quality of life, decrease in number of infectious complications and perfection of the medical help to sick women with frequent recidives an infection of the bottom department of sexual ways.


About the authors

I. S. Sidorova

First Moscow state medical university of I.M. Sechenov

Author for correspondence.
Email: khristina79@yandex.ru

Russian Federation доктор медицинских наук, профессор, член-корр. РАМН, заслуженный деятель науки РФ, заведующая кафедрой акушерства и гинекологии № 1 лечебного факультета ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздравсоцразвития России Адрес: 119991, Москва, ул. Трубецкая, д. 8, стр. 2 Тел.: (499) 248-67-38

Kh. A. Belopol'skaya

First Moscow state medical university of I.M. Sechenov

Email: khristina79@yandex.ru

Russian Federation аспирант кафедры акушерства и гинекологии № 1 лечебного факультета ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздравсоцразвития России Адрес: 119991, Москва, ул. Трубецкая, д. 8, стр. 2

References

  1. Anastas’eva V.G. Sovremennye metody diagnostiki, lecheniya i profilaktiki bakterial’nogo vaginoza. Novosibirsk: NMN. 1997. 152 s.
  2. Afanas’ev M.S. Kompleksnoe lechenie tservikal’noi intraepitelial’noi neoplazii u patsientok posle perenesennogo genital’nogo khlamidioza. Avtoref. diss. … dokt. med. nauk. 2006. 131 s.
  3. Tikhomirov A.L., Sarsaniya S.I. Kompleksnoe lechenie smeshannykh genital’nykh infektsii. Ginekologiya. 2004; 6 (6): 196–201.
  4. Klaenhammer T.R. Probiotic Bacteria. Today and Tomorrow. J. Nutrition. 2000; 130: 415–416.
  5. Akaeva F.S., Omarova S.M., Adieva L.A. Mnozhestvennaya antibiotikorezistentnost’ assotsiativnoi mikroflory pri urogenital’noi patologii. ZhMEI. 2008;
  6. : 85–89. 6. Prilepskaya V.N., Bairamova G.R. Etiopatogenez, diagnostika i sovremennye napravleniya v lechenii bakterial’nogo vaginoza. RMZh.2002; 10 (18): 14–16.
  7. Franklin T.L., Monif G.R. Trichomonas vaginalis and bacterial vaginosis. Coexistence in vaginal wet mount preparations from pregnant women. J. Reprod. Med. 2000; 45. 2: 131–134.
  8. Borovkova E.I. Vzaimodeistvie vozbuditelya infektsii s organizmom beremennoi kak faktor riska vnutriutrobnogo infitsirovaniya ploda. Diss ... kand.med.nauk. Moskva. 2004. 197 s.
  9. Dmitriev G.A. Urogenital’nye bakterial’nye infektsii: diagnostika, lechenie i profilaktika zabolevanii, peredavaemykh polovym putem. Infektsii i antimikrobnaya terapiya. 2003; 5 (1): 5–11.
  10. Prilepskaya V.N., Rudakova E.B., Kononov A.V. Ektopii i erozii sheiki matki. M.: MEDpress-inform. 2002. 175 s.
  11. Sidorova I.S. Pozdnii gestoz. M.: Meditsina. 1996. 222 s.
  12. Tyutyunnik V.L. Akusherskie oslozhneniya i perinatal’nye iskhody u patsientok s bakterial’noi i/ili virusnoi infektsiei. Problemy beremennosti. 2001; 2: 51–54.
  13. Vorob’ev A.A. Immunomodulyatory: printsipy klassifikatsii i strategiya primeneniya v meditsine. Vestn. RAMN. 2002; 4: 3–5.
  14. Dolgushin I.I., Andreeva Yu.S. Rol’ neitrofilov v regulyatsii mikrobiotsenoza reproduktivnogo trakta zhenshchin. Mikrobiologiya. 2005; 5: 84–87.
  15. Pastore L.M., Thorp J.M., Royce R. et al. Risk score for antenatal bacterial vaginosis: BV PIN Points. J. Perinatol. 2002; 22 (2): 125–132.
  16. Strizhakov A.N., Podzolkova I.M. Gnoino-vospalitel’nye zabolevaniya pridatkov matki. Moskva. 1996. 325 s.
  17. Uvarova E.V., Sultanova F.Sh. Vlagalishche kak mikroekosistema v norme i pri vospalitel’nykh protsessakh genitalii razlichnoi etiologii. Ginekologiya. 2002; 4 (4): 189–195.
  18. Frolova I.I., Babichenko I.I., Mestergazi G.M. Tservikal’nye intraepitelial’nye neoplazii i diskeratozy sheiki matki. — M: Dinastiya. 2004. 79 s.
  19. Bondarenko V.M., Vorob’ev A.A. Disbiozy i preparaty s problematicheskoi funktsiei. Zhurn. mikrobiologii, epidemiologii i immunobiologii. 2004; 1: 84–92.
  20. Medvedev B.I., Zainetdinova L.F., Teplova S.N. Mikroflora organov reproduktivnoi sistemy u zhenshchin s trubno-peritoneal’nym besplodiem. ZhMEI. 2008; 3: 58–62.
  21. Salim R., Ben-ShlomoI., Colodner R. et al. Bacterial colonization of the uterine cervix and success rate in assisted reproduction: results of a prospective survey. Human Reprod. 2002; 17 (2): 337–340.
  22. Valyshev A.V., Elagina N.N., Bukharin O.V. Anaerobnaya mikroflora zhenskogo reproduktivnogo trakta. ZhMEI. 2001; 4: 78–84.
  23. Catlin B.W. Gardnerella vaginalis: character-ristics, clinical considerations, and controversies. Clin.Microbiol. Rev. 1992; 5 (3): 213–237.
  24. Ugwumadu A.H. Bacterial vaginosis in pregnancy. Curr. Opin. Obstet. Gynecol. 2002; 14 (2): 115–118.
  25. Dolgushin I.I., Andreeva Yu.S., Plekhanova E.V. Vzaimodeistvie neitrofilov s razlichnymi bakterial’nymi agentami. Mikrobiologiya. 2008; 5: 103–105.
  26. Khaitov R.M., Pinegin B.S. Sovremennye predstavleniya o zashchite organizma ot infektsii. Immunologiya. 2000; 1: 61–64.
  27. Besednova N.N. Regulyatsiya immunnykh protsessov peptidami prirodnogo proiskhozhdeniya. Antibiotiki i khimioterapiya. 1999; 44 (1): 31–34.
  28. Karaulov A.V., Kalyuzhnyi O.V. Tsitokiny: biologicheskoe deistvie i klinicheskoe primenenie. Uspekhi klinicheskoi immunologii i allergologii. 2000; 1: 113–205.
  29. Santoni G., Boccanera M., Adriani D. et al. Immune cell-mediated protection against vaginal candidiasis: evidence for a major role of vaginal CD4(+) T cells and possible participation of other local lymphocyte effectors. Infect. Immunol. 2002; 70 (9): 4791–4797.
  30. Likhachev V.K. Prakticheskaya ginekologiya. M., MIA. 2007. 663 s
  31. Konstantinova O.D., Kremleva E.A., Cherkasov S.V. Mikroflora reproduktivnogo trakta zhenshchin pri vnutrimatochnykh vmeshatel’stvakh. ZhMEI. 2000; 2: 98–100.
  32. Kalugina M.Yu., Karazhas N.V., Kozina V.I. Gerpeticheskie infektsii u bol’nykh s immunodefitsitnym sostoyaniem. ZhMEI. 2009; 1: 79–80.
  33. Zemskov A.M., Karaulov A.V., Zemskov V.M. Kombinirovannaya immunokorrektsiya. M.: Nauka. 1994. 260 s.
  34. Melikhova N.Yu. Virusnye porazheniya genitalii u zhenshchin. Moskva. 2005. 66 s.
  35. Kulakov V.I., Aleshkin V.A., Bogdanova E.A. Biotsenoz vlagalishcha i faktory mestnogo immuniteta. Posobie dlya vrachei. Moskva. 2000. 24 s.
  36. Semenova T.V. Genital’nyi gerpes u zhenshchin. RMZh. 2001; 9 (6): 237–242.
  37. Vollard E.I., Clasner H.A.L. Colonization resistance. Antimicrob. Agents Chemother. 1994; 38: 409–414.
  38. Senchuk A.Ya., Mikhal’skii L.A., Rogacheva V.P. Pokazateli mestnogo gumoral’nogo immuniteta do i posle lecheniya vospalitel’nykh zabolevanii sheiki matki i vlagalishcha preparatom «Terzhinan». Praktikuyushchii vrach. 2004; 3: 40–42.
  39. Minkina G.N., Manukhin I.B., Frank G.A. Predrak sheiki matki. M.: Aerograf-Media. 2001. 112 s.
  40. Prilepskaya V.N., Rogovskaya S.I., Mezhevitinova S.A. Kol’poskopiya. Prakticheskoe rukovodstvo. M: MIA. 2001. 100 s.
  41. Rogovskaya S.I., Prilepskaya V.N. Bakterial’nyi vaginoz i papillomavirusnaya infektsiya. Ginekologiya. 2002; 4 (3): 126–130.
  42. Hashido M., Lee F.K., Naihmias A.J. et al. An epide-miologicstudy of herpes simplex virustype 1 and 2 infection in Japan4 based on type-specific serological assays. Epidemiol. Inf. 1998; 120: 179–186.
  43. Repin I.V. Kliniko-immunologicheskaya effektivnost’ preparatov amiksin i galavit v lechenii vospalitel’nykh zabolevanii pridatkov matki. Avtoref. diss…. kand. med. nauk. Moskva. 2001. 33 s.
  44. Buyanova S.N., Shchukina N.A., Peskova E.O., Nikogosyan S.D. Opyt primeneniya galavita u ginekologicheskikh bol’nykh s gnoinymi vospalitel’nymi zabolevaniyami organov malogo taza. Trudy Mezhdunar. kongressa «Immunitet i bolezni: ot teorii k terapii». Moskva. 2005. 24–25 s.
  45. Shul’zhenko A.E., Zuikova I.N. Galavit v kompleksnoi terapii bol’nykh s khronicheskoi retsidiviruyushchei gerpesvirusnoi infektsiei. Novye lekarstva. 2003; 3: 54–57.
  46. Kushch A.A. Deistvie preparata panavir na sintez belkov virusa prostogo gerpesa 1 i 2 tipov v kletkakh, zarazhennykh in vitro. Opyt primeneniya panavira v lechebnoi praktike (ginekologiya). Moskva. 2008. 7–10 s.
  47. Zarcone R., Bellini P., Cardone G. et al. Associazione di interleuchina-2 ed interferon-alpha nel trattamento della condilomatosi della cervice uterine. Minerva ginecol. 1996;
  48. (3): 111–113. 48. Semenova T.V., Gubanova E.I., Yatsukha M.V. Epidemiologicheskie aspekty genital’nogo gerpesa. Analiz zabolevaemosti genital’nym gerpesom v Rossiiskoi Federatsii i v g. Moskve za period s 1994 po 1998 gg. Moskva. 2000; 6: 26–30.
  49. Baumgartner J.D., Glauser M.P. Immunotherapy of endotoxemia and septicemia. Immunology. 1993; 187 (315): 464–477.
  50. Erickson K.L., Hubbard N.E. Probiotic immunomodulation in health and disease. J. Nutr. 2000; 130: 403–409.
  51. Bondarenko V.M., Rubakova E.I., Lavrova V.A. Immunostimuliruyushchee deistvie laktobakterii, ispol’zuemykh v kachestve osnovy preparatov probiotikov. Zhurn. mikrobiologii. 1998; 5: 107–112.
  52. Adams M. Bakteriofagi. Per. s angl. M: Inostr. lit-ra. 1961. 527 s.
  53. Aslanov B.I., Yafaev R.Kh., Zueva L.P. Puti ispol’zovaniya sinegnoinykh bakteriofagov v lechebnoi i protivoepidemicheskoi praktike. Zhurn. mikrobiol. 2003; 5: 72–76.
  54. Krylov V.N. Ambivalentnye bakteriofagi raznykh vidov, aktivnye na shtammakh Escherichia coli K 12 i Salmonella sp. Genetika. 2006; 42 (2): 159–168.
  55. Bragina L.E., Vasil’eva L.I. Disbiozy zhenskoi polovoi sfery pri nespetsificheskikh vaginitakh. Disbakteriozy i eubiotiki: tez. dokl. Moskva. 1996. 8 s.
  56. Khairulin I.N. Rol’ mikroflory khirurgicheskogo otdeleniya v razvitii posleoperatsionnykh oslozhnenii khirurgicheskikh ran i ikh korrektsiya s pomoshch’yu bakteriofagov. Avtoref. diss. … kand. med. nauk. Kazan’. 2003. 19 s.
  57. Lazareva E.B. Bakteriofagi i pektiny v korrektsii narushenii mikrobiotsenozov pri gnoino-vospalitel’nykh protsessakh. Diss … d.m.n. Moskva. 2007. 200 s.
  58. Morev S.I. Vliyanie yablochnykh pektinov na adgezivnost’ i razvitie mikroflory kishechnika cheloveka. Vestnik Ivanovskoi meditsinskoi akademii. 2000; 5 (3–5): 39–43.
  59. Pyatchina O.V. Eksperimental’naya i klinicheskaya otsenka preparatov pektinov i al’ginatov pri pochechnoi nedostatochnosti. Avtoref. diss… kand. med. nauk. Vladivostok. 2004. 24 s.
  60. Shchepetkin I.A. Aktivatsiya makrofagov rastitel’nymi polisakharidami. Antibiotiki i khimioterapiya. 2004; 49 (1): 35–42 s.
  61. Potievskii E.G., Novikov A.I. Meditsinskie aspekty primeneniya pektina. M: Med. kniga. 2002. 96 s.
  62. Khryanin A.A., Reshetnikov O.V. Azitromitsin (sumamed) v lechenii khlamidiinoi infektsii pri vospalitel’nykh zabolevanii organov malogo taza. Trudnyi patsient. 2008; 6 (1): 4–8.
  63. Abramenko V.V. Antibiotiki v akusherstve i ginekologii / Pod red.V.V. Abramenko, N.A. Bashmakova, V.V. Korkhov. S.-Pb.: Spets. lit. 2000. 219 s.
  64. Berlev I.V., Kira E.F., Belevitina A.A. Rol’ disbioticheskikh narushenii vlagalishcha v razvitii infektsionno-vospalitel’nykh oslozhnenii novorozhdennykh. Zh. Akusherstva i zhenskikh boleznei. 2000; 4: 58–61.
  65. Pynzar’ M.A., Agikova L.A., Minkina G.N. Opyt klinicheskogo primeneniya immunomodulyatora likopida u bol’nykh s bakterial’nym vaginozom. Immunologiya. 1998; 5: 63–64.
  66. Abubakirova A.M., Fedorova T.A., Foteeva T.S. i dr. Primenenie meditsinskogo ozona v klinike akusherstva i ginekologii. Akusherstvo i ginekologiya. 2002; 1: 54–57.
  67. Grechkanev G.O., Kachalina O.V. Ispol’zovanie ozonoterapii v lechenii nespetsificheskogo kol’pita i bakterial’nogo vaginoza. Akusherstvo i ginekologiya. 2001; 6: 59–60.
  68. Yanshin D.V. Oksigenirovannye rastvory v kompleksnoi detoksikatsii i biokorrektsii organizma. Funktsional’noe pitanie, pishchevaya bezopasnost’ i zdorov’e lyudei v usloviyakh megapolisa. Simpozium. Moskva. 2003. 77–80 s.
  69. Demlov R., Yungmann M.-T. Rukovodstvo po kislorodnoi i ozonoterapii (praktika – klinika – nauchnye osnovy). M.: «Arnebiya». 2005. 207 s.
  70. Malevich K.I., Rusakevich P.S. Lechenie i reabilitatsiya pri ginekologicheskikh zabolevaniyakh: Spravochnoe posobie. Minsk: Vyssh. Shkola. 1994. 368 s.

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