IgE-RESPONSE AFTER ADMINISTRATION OF PANDEMIC VACCINE STRAIN A/CALIFORNIA/7/2009 (H1N1) v

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Abstract


Changes in total and allergy-specific IgE (IgE-antibodies) in 70 healthy volunteers vaccinated with influenza vaccine subunit strain A/California/7/2009/(H1N1). Safety of this vaccine was shown. Repeated second dose administration is not accompanied by increase in IgE-antibodies to egg components. Vaccine injection results in decrease of total IgE in patients with elevated IgE at baseline.

 


M. P. Kostinov

Russian Academy of Medical Sciences (RAMS) Mechnicov Reseach Institute of Vaccines and Sera

Author for correspondence.
Email: vaccine@bk.ru

Russian Federation доктор медицинских наук, профессор, Заслуженный деятель науки РФ, заведующий лабораторией вакцинопрофилактики и иммунотерапии аллергических заболеваний НИИВС им. И.И. Мечникова РАМН Адрес: 105064, Москва, Малый Казенный пер., д. 5-а Тел., факс: (495) 917-41-49

O. A. Terkacheva

Russian Academy of Medical Sciences (RAMS) Mechnicov Reseach Institute of Vaccines and Sera

Email: lylygin@rambler.ru

Russian Federation аспирант НИИВС им. И.И. Мечникова РАМН Адрес: 105064, Москва, Малый Казенный пер., д. 5-а

S. N. Zhirova

Russian Academy of Medical Sciences (RAMS) Mechnicov Reseach Institute of Vaccines and Sera

Email: svaccina@mail.ru

Russian Federation ведущий научный сотрудник НИИВС им. И.И. Мечникова РАМН Адрес: 105064, Москва, Малый Казенный пер., д. 5-а Тел., факс: (495) 917-41-49

A. P. Cherdanchev

Ulyanovsk State University

Email: niti@ulsu.ru

Russian Federation научный сотрудник кафедры педиатрии Ульяновского государственного университета Адрес: 432700, Ульяновск, ул. Л. Толстого, д. 42 Тел.: (8422) 41-20-88; факс: (8422) 41-23-40

M. K. Erofeeva

Research Institute of Influenza, St. Petersburg

Email: office@influenza.spb.ru

Russian Federation старший научный сотрудник НИИ гриппа МЗиСР РФ Адрес: 197376, Санкт-Петербург, ул. проф. Попова, д. 15/17 Тел.: (812) 234-62-00; факс: (812) 234-59-00

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