TWO PATTERNS ОF CT-BRAIN PERFUSION AND DC-POTENTIALS ОF THE BRAIN EVOKED COGNITIVE TASK IN DISCIRCULATORY ENCEPHALOPATHY PATIENTS

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Abstract

In patients with discirculatory encephalopathy the influence of verbal fluency test on the characteristics of cerebral perfusion, DC-potentials of the brain, as well as on blood pressure and heart rate was investigated. Two patterns of responses to the verbal fluency test were observed. The first one is the process of generalized activation, manifested by the reduction of the TTP (time to peak) parameters of brain perfusion, the rise of the DC-potentials in all areas of brain and the modulation of blood pressure and heart rate. The second process, directly connected with cognitive processing, was manifested by the shifts of local characteristics of brain perfusion and DC-potentials in the frontal, temporal and central cortex, especially in the left hemisphere. Correlations were found between the characteristics of cerebral perfusion and DC-potentials on the one hand and the number of words during the verbal fluency test performance on the other hand.

 

About the authors

V. F. Fokin

Research Center of Neurology of Russian academy of medical science, Moscow

Author for correspondence.
Email: fvf@mail.ru
доктор биологических наук, профессор, руководитель лаборатории возрастной физио- логии мозга Научного центра неврологии РАМН Адрес: 125367, Москва, Волоколамское ш., д. 80 Тел.: (495) 917-07-65 Россия

N. V. Ponomareva

Research Center of Neurology of Russian academy of medical science, Moscow

Email: ponomare@yandex.ru
доктор медицинских наук наук, ведущий научный сотрудник лаборатории воз- растной физиологии мозга Научного центра неврологии РАМН Адрес: 125367, Москва, Волоколамское ш., д. 80 Тел.: (495) 917-07-65 Россия

M. V. Krotenkova

Research Center of Neurology of Russian academy of medical science, Moscow

Email: in-ray@yandex.ru
доктор медицинских наук, руководитель отделения лучевой диагностики Научного центра неврологии РАМН Адрес: 125367, Москва, Волоколамское ш., д. 80 Тел.: (495) 490-22-05, факс: (495) 490-41-71 Россия

R. N. Konovalov

Research Center of Neurology of Russian academy of medical science, Moscow

Email: in-ray@yandex.ru
кандидат медицинских наук, старший научный сотрудник отделения лучевой диагностики Научного центра неврологии РАМН Адрес: 125367, Москва, Волоколамское ш., д. 80 Тел.: (495) 490-22-05, факс: (495) 490-41-71 Россия

M. M. Tanashyan

Research Center of Neurology of Russian academy of medical science, Moscow

Email: angionev@gmail.com
доктор медицинских наук, профессор, зам. директора по научной и лечебной работе, руководитель 1-го сосудистого отделения (общей ангионеврологии) Научного центра неврологии РАМН Адрес: 125367, Москва, Волоколамское ш., д. 80 Тел.: (495) 490-24-02, факс: (495) 490-22-10 Россия

O. V. Lagoda

Research Center of Neurology of Russian academy of medical science, Moscow

Email: angionev@gmail.com
кандидат медицинских наук, старший научный сотрудник 1-го сосудистого отделения (общей ангионеврологии) Научного центра неврологии РАМН Адрес: 125367, Москва, Волоколамское ш., д. 80 Тел.: (495) 490-24-02, факс: (495) 490-22-10 Россия

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