PECULIARITIES OF CEREBRAL STRUCTURES FUNCTIONING IN ADOLESCENTS WITH ACHONDROPLASIA

Cover Page


Cite item

Full Text

Abstract

Complex neurophysiological examination (rheoencephalography, electroencephalography) was carried out in 12 adolescents 12 to 18 years old in order to reveal the peculiarities of cerebral structures functioning in adolescents with achondroplasia. Some deviations from the normal values were found out: reduced blood filling of the brain vessels in the pools of a. carotis interna and a. vertebralis, rheoencephalographic signs of intracranial hypertension of mild degree and brain cycling characterized by moderate and significant amplitude increase, presence of pathological types (δ-, θ-) of the rhythmics and the reduction of the physiological ones (α-, β-). At the same time the peculiarities of rheoencephalographic indices were observed while functional testings (hypercapnia, hyperoxia). Brain cycling differed from normal values by weaker response to the weight-bearing, mainly in α- and β-ranges.

 

About the authors

A. A. Skripnikov

Russian Ilizarov Scientific Center «Restorative Traumatology and Orthopaedics, Kurgan, Russian Federation

Author for correspondence.
Email: skripnikov2007@mail.ru
PhD, Research Worker of Laboratory of Physiology of motion and neurophysiology «Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics»  Address: 640014, Kurgan, M. Ul'yanovoi St., 6; tel.: (3522) 23-04-81 Россия

Т. I. Dolganova

Russian Ilizarov Scientific Center «Restorative Traumatology and Orthopaedics, Kurgan, Russian Federation

Email: rjik532007@rambler.ru

PhD, Senior Research Worker of Laboratory of functional studies «Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics» Address: 640014, Kurgan, M. Ul'yanovoi St., 6; tel.: (3522) 45-27-36, 45-42-86

Россия

А. M. Аranovich

Russian Ilizarov Scientific Center «Restorative Traumatology and Orthopaedics, Kurgan, Russian Federation

Email: office@ilizarov.ru

PhD, Professor, Head of Department 15 (cosmetic surgery, achondroplasia) «Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics» Address: 640014, Kurgan, M. Ul'yanovoi St., 6; tel.: (3522) 45-03-39

Россия

References

  1. DiMario F.J. Jr., Ramsby G.R., Burleson J.A., Greensheilds I.R. Brain morphometric analysis in achondroplasia. Neurology. 1995; 45 (3): 519–524.
  2. Pierre-Kahn A., Hirsch J.F., Renier D., Metzger J., Maroteaux P. Hydrocephalus and achondroplasia. A study of 25 observation. Childs Brain. 1980; 7 (4): 205–219.
  3. Aryanpur J., Hurco O., Francomano C., Wang H., Carson B. Craniocervical decompression for cervicomedullary compression in pediatric patients with achondroplasia. Neurosurg. 1990; 73 (3): 375–382.
  4. Gordon N. The neurological complication of achondroplasia. Brain Dev. 2000; 22 (1): 3–7.
  5. Thompson N.M., Hecht J.T., Bohan T.P., Kramer L.A., Davidson K., Brandt M.E., Fletcher J.M. Neuroanatomic and neurophsychological outcom in scholl-age children with achondroplasia. Am. J. Med. Genet. 1999; 88 (2): 145–153.
  6. Ruis-Garcia M., Tovar-Baudin A., Del Castilio-Ruis V., Rodriguez H.P., Collado M.A., Mora T.M., Rueda-Franco F., Gonzalez-Astiazaran A. Early detection of neurological manifestation in achondroplasia. Childs Nerv. Syst. 1997; 13 (4): 208–213.
  7. Ivanov L.B., Makarov V.A. Lektsii po klinicheskoi reografii [Lectures on Clinical Rheography]. Moscow, AOZT «Antidor», 2000. 320 p.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 1970 "Paediatrician" Publishers LLC



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies