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Вестник Российской академии медицинских наук

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ЦЕРЕБРОЛИЗИН В ЛЕЧЕНИИ ОСТРОГО ИШЕМИЧЕСКОГО ИНСУЛЬТА

https://doi.org/10.15690/vramn.v68i1.533

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Аннотация

В обзоре обсуждаются существующие доказательства пользы и рисков применения церебролизина ― смеси низкомолекулярных пептидов и аминокислот, полученных из мозговой ткани свиней, с заявленными нейропротективными и нейротрофическими свойствами для лечения острого ишемического инсульта. Авторами проведен систематический поиск и анализ рандомизированных контролируемых клинических испытаний, сравнивающих церебролизин с плацебо у пациентов с острым ишемическим инсультом. На основании критического анализа и оценки пригодности для систематического рассмотрения авторами выбрано единственное исследование, удовлетворяющее критериям качества. Показано отсутствие различий между церебролизином и плацебо по влиянию на смерть и неблагоприятные события. Обоснован вывод об отсутствии достаточных доказательств влияния церебролизина на выживаемость и инвалидизацию при остром ишемическом инсульте.

 

Об авторах

Л. Е. Зиганшина
Казанский (Приволжский) федеральный университет, Республика Татарстан, Российская Федерация
Россия


Т. Р. Абакумова
Казанский (Приволжский) федеральный университет, Республика Татарстан, Российская Федерация
Россия


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Для цитирования:


Зиганшина Л.Е., Абакумова Т.Р. ЦЕРЕБРОЛИЗИН В ЛЕЧЕНИИ ОСТРОГО ИШЕМИЧЕСКОГО ИНСУЛЬТА. Вестник Российской академии медицинских наук. 2013;68(1):21-29. https://doi.org/10.15690/vramn.v68i1.533

For citation:


Ziganshina L.Е., Abakumova T.R. CEREBROLYSIN FOR ACUTE ISCHEMIC STROKE. Annals of the Russian academy of medical sciences. 2013;68(1):21-29. (In Russ.) https://doi.org/10.15690/vramn.v68i1.533

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