Diagnostic Possibilities of Magnetic Resonance Cholangiography with Intravenous Contrast in Diseases of the Bile Ducts

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Abstract

Every year the number of operations on the hepatobiliary zone is steadily increasing due to diseases of the bile ducts. Against this background, there is a need for an accurate diagnosis of complications of these interventions; classical magnetic resonance cholangiopancreatography (MRCP) is of limited use. With the introduction of a liver-specific contrast agent (Gd-EOB-DTPA), the possibility of diagnosing diseases of the bile ducts has expanded. In this clinical review, we review the technical aspects and benefits of Gd-EOB-DTPA-enhanced MR cholangiography. Various types of contrast agents, methods of their use in MRI, the dependence of the signal intensity in the bile ducts on the time of administration of the substance, the presence of chronic liver diseases are covered in detail. Separately, studies are given on the diagnosis of diseases of the bile ducts with altered biliary anatomy, biliary fistulas after surgical interventions. In conclusion, data are presented on promising studies of the functional state of the liver based on the use of MRI with hepatotropic contrast enhancement.

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About the authors

Grigoriy G. Karmazanovsky

Vishnevsky National Medical Research Center of Surgery

Email: karmazanovsky@ixv.ru
ORCID iD: 0000-0002-9357-0998
SPIN-code: 5964-2369

MD, PhD, Professor, Corresponding Member of the RAS

Russian Federation, Mosсow

Alexey V. Chzhao

Vishnevsky National Medical Research Center of Surgery

Email: chzhao@ixv.ru
ORCID iD: 0000-0002-0204-8337
SPIN-code: 1101-6874

MD, PhD, Professor

Russian Federation, Mosсow

Khachatur A. Ayvazyan

Vishnevsky National Medical Research Center of Surgery

Email: ayvazyan@ixv.ru
ORCID iD: 0000-0002-4115-6963
SPIN-code: 3954-7051

Researcher Associate

Russian Federation, Mosсow

Anton B. Goncharov

Vishnevsky National Medical Research Center of Surgery

Email: goncharov@ixv.ru
ORCID iD: 0000-0002-3528-036X
SPIN-code: 1749-7490

Researcher Associate

Russian Federation, Mosсow

Veronika A. Saraeva

Vishnevsky National Medical Research Center of Surgery

Email: saraeva@ixv.ru
ORCID iD: 0000-0003-4273-171X

PhD Student

Russian Federation, Mosсow

Sergey A. Trifonov

Vishnevsky National Medical Research Center of Surgery

Author for correspondence.
Email: trifonov@ixv.ru
ORCID iD: 0000-0003-1176-1203
SPIN-code: 7877-1999

MD

Russian Federation, Mosсow

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Supplementary files

Supplementary Files
Action
1. Figure 1. MR cholangiograms in E-thrive, axial, coronary phases 30 min after injection of a hepatocontrast agent (primovist). Condition after resection of IV, V segments of the liver. The bile ducts are rich, there is no data for extravasation of the contrast agent into the abdominal cavity, free evacuation into the duodenum. A is a frontal view. B - axial projection.

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