Постспленэктомический гипоспленизм

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Аннотация

Спленэктомия — это серьезная иммунокомпрометирующая операция, т.к. в результате нее удаляется наиболее крупный периферический орган иммунной системы, из организма выносится огромный массив пулов различных иммуннокомпетентных клеток и иммунноактивных факторов, страдают и специфические, и неспецифические врожденные звенья иммунитета. Место гипоспленизма в педиатрии в России не определено: не существует ни четких критериев его диагностики, ни утвержденных алгоритмов профилактики. Статистические данные о частоте развития постспленэктомического сепсиса в России отсутствуют. В данной обзорной статье авторы приводят современные литературные данные относительно вопросов гипоспленизма и изменений, развивающихся в организме после удаления селезенки. Обсуждается системный эффект органоуносящей операции, рассматриваются основные направления профилактики отягощенной постспленэктомической инфекции и сепсиса как крайней степени проявления гипоспленизма.

Об авторах

Дмитрий Анатольевич Морозов

Научный центр здоровья детей;
Первый МГМУ им. И.М. Сеченова

Автор, ответственный за переписку.
Email: damorozov@list.ru

доктор медицинских наук, профессор, директор НИИ детской хирургии НЦЗД;

заведующий кафедрой детской хирургии и урологии-андрологии,

119991, Москва, Ломоносовский пр-т, д. 2, стр. 1

Россия

Сергей Александрович Клюев

Научный центр здоровья детей

Email: sergey1klyuev@yandex.ru

врач-детский хирург, аспирант НЦЗД,

119991, Москва, Ломоносовский пр-т, д. 2, стр. 1

Россия

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