Hyposlenism After Splenectomy

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Abstract

Splenectomy is a serious operation, which includes the removal of the largest peripheral immune organ. Vast array of different pools of immunocompetent cells and immune-factors eliminate from the body as a result of this operation. Occurrence of hyposplenism in our country pediatric service is not determined — there are neither clear criteria for its diagnosis, nor approved algorithms for prevention. Data of postsplenectomy sepsis incidence in Russia are unknown. In this review article authors give contemporary literature data relating to the issue of developing hyposplenism and changes in the body after removal of spleen. Systemic effect of organ-resecting operation and the basic directions of overwhelming post-splenectomy infection and sepsis prevention are discussed.

About the authors

D. A. Morozov

Scientific Centre of Children’s Health;
Sechenov First Moscow State Medical University

Author for correspondence.
Email: damorozov@list.ru
Moscow Russian Federation

S. A. Klyuev

Scientific Centre of Children’s Health

Email: sergey1klyuev@yandex.ru
Moscow Russian Federation

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