АКТУАЛЬНЫЕ ВОПРОСЫ КЛЕТОЧНОЙ ТЕРАПИИ МИОКАРДА

Обложка


Цитировать

Полный текст

Аннотация

В данной работе проводится анализ литературных и собственных результатов исследований в области клеточной терапии миокарда. Сформулированы основные нерешенные вопросы данной области регенеративной медицины.  

 

Об авторах

Д. В. Гольдштейн

ФГБУ "Медико-генетический научный центр" РАМН, Москва
ЗАО «РеМеТэкс», Москва

Автор, ответственный за переписку.
Email: dv@rm7.ru
доктор биологических наук, профессор, руководитель лаборатории генетики ство- ловых клеток МГНЦ РАМН, генеральный директор ЗАО «РеМеТэкс» Адрес: 115478, Москва, Каширское шоссе, д. 24, стр. 2 Тел.: (495)324-20-24 Россия

Т. Х. Фатхудинов

ФГБУ "НИИ морфологии человека" РАМН, Москва
ЗАО «РеМеТэкс», Москва

Email: fatkhudinov@gmail.com
кандидат медицинских наук, в.н.с. лаборатории роста и развития НИИМЧ РАМН, в.н.с. ЗАО «РеМеТэкс» Адрес: 115478, Москва, Каширское шоссе, д. 24, стр. 2 Тел.: (499) 503-96-38 Россия

Список литературы

  1. Thomson J., Itskovitz-Eldor J., Shapiro S. et al. Embryonic Stem Cell Lines Derived from Human Blastocysts. Science. 1998; 6 November: 1145–1147.
  2. Kharchenko V. I., Kakorina E. P., Koryakin M. V. i dr. Smertnost’ ot serdechno-sosudistykh zabolevanii v Rossii i v ekonomicheski razvitykh stranakh. Neobkhodimost’ usileniya kardiologicheskoi sluzhby i modernizatsii meditsinskoi statistiki v Rossiiskoi Federatsii (analiticheskii obzor ofitsial’nykh dannykh Goskomstata, Minzdrava Rossii, VOZ i ekspertnykh otsenok po probleme). Rossiiskii kardiologicheskii zhurnal. 2005; № 1 (51): 5–15.
  3. Koroteev A.V., Belyanko I.E.. Khirurgicheskoe lechenie serdechnoi nedostatochnosti. In: Tereshchenko S.N., editor. Nekotorye nereshennye voprosy khronicheskoi serdechnoi nedostatochnosti. Moskva. 2007: 204–223.
  4. Belenkov Yu.N., Oganov R.G.. Kardiologiya. Natsional’noe rukovodstvo. Moskva: Geotar-media. 2007.
  5. Shumakov V.I., Khubutiya M.Sh. Dilatatsionnaya kardiomiopatiya. Moskva. 2003.
  6. Annarosa L. , Kajstura J., Anversa P. Cardiac Stem Cells and Mechanisms of Myocardial Regeneration. Physiol. Rev. 2005; 85: 1373–1416.
  7. Rumyantsev P.P. Kardiomiotsity v protsessakh reproduktsii, differentsirovki i regeneratsii. L.: Nauka. 1982: 288 s.
  8. van Amerongen M.J., Engel F.B. Features of cardiomyocyte proliferation and its potential for cardiac regeneration. J. Cell Mol. Med. 2008 Dec;12(6A):2233–44.
  9. Thiele1 J., Varus E., Wickenhauser C. et al. Regeneration of heart muscle tissue: quantification of chimeric cardiomyocytes and endothelial cells following transplantation. Histol. Histopathol. 2004. 19: 201–209.
  10. ten Hove W.R., Verspaget H.W., Barge R. et al. Liver chimerism after allogeneic blood stem cell transplantation. Transplant. Proc. 2007 Jan-Feb; 39(1):231–236.
  11. Zhang M., Methot D., Poppa V. et al. Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J. Mol. Cell. Cardiol. 2001; 33(5):907–921.
  12. Makino S., Fukuda K., Miyoshi S. et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J. Clin. Invest. 1999;103(5):697–705.
  13. Passier R., van Laake L., Mummery C. Stem-cell-based therapy and lessons from the heart. Nature. 2008; 453(15): 322–329. 1
  14. Orlic D., Kajstura J., Chimenti S. et al. Bone marrow cells regenerate infarctedmyocardium. Nature. 2001; 410 (5): 701–705.
  15. Dai1 W., Hale S., Kloner R. Role of a paracrine action of mesenchymal stem cells in the improvement of left ventricular function after coronary artery occlusion in rats. Regenerative Med. 2007; 2(1): 63–68.
  16. Stamm C., Nasseri B., Choi Y.H. et al. Cell therapy for heart disease: great expectations, as yet unmet. Heart Lung Circ. 2009 Aug;18(4):245–56.
  17. Baikova Yu.P., Fatkhudinov T.Kh., Bol’shakova G.B. i dr. Reparatsiya miokarda pri transplantatsii mononuklearnykh kletok kostnogo mozga. Kletochnye tekhnologii v biologii i meditsine. 2010; 4: 203–211.
  18. Bochkov N.P., Nikitina V.A. Tsitogenetika stvolovykh kletok cheloveka. Molekulyarnaya meditsina. 2008; 3: 40-47.
  19. Wollert K., Drexler H. Cell therapy for the treatment of coronary heart disease: a critical appraisal. Nat. Rev. Cardiol. 2010; 7:204– 215.
  20. Fatkhudinov T.Kh., D’yachkov A.V., Koroteev A.V. i dr. Bezopasnost’ i effektivnost’ transplantatsii allogennykh mul’tipotentnykh stromal’nykh kletok pri khirurgicheskom lechenii dilatatsionnoi kardiomiopatii. Kletochnye tekhnologii v biologii i meditsine. 2010; 1: 10–17.
  21. Kellar R., Landeen L., Shepherd B. et al. Scaffold-Based ThreeDimensional Human Fibroblast Culture Provides a Structural Matrix That Supports Angiogenesis in Infarcted Heart Tissue. Circulation. 2001;104:2063–2068.
  22. Reinecke H., MacDonald G., Hauschka S. et al. Electromechanical coupling between skeletal and cardiac muscle. Implications for infarct repair. J. Cell Biol. 2000, 149(3):731–740.
  23. Menasche P. Cell-based Therapy for Heart Disease: A Clinically Oriented Perspective. Molecular Therapy. 2009; 17(5): 758–766.
  24. Meyer G., Wollert K., Steffens L. et al. Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months’ followup data from the randomized, controlled BOOST (BOne marrow transfer to enhance ST-elevation infarct regeneration) trial. Circulation. 2002; 113: 1287–1294.
  25. Schachinger V., Assmus B., Honold J. et al. Normalization of coronary blood flow in the infarct-related artery after intracoronary progenitor cell therapy: intracoronary Doppler substudy of the TOPCARE-AMI trial. Clin. Res. Cardiol. 2006 Jan; 95(1): 13–22
  26. Hofmann M., Wollert K., Meyer G. et al. Monitoring of bone marrow cell homing into the infarcted human myocardium. Circulation. 2005;111(17):2198–2202.
  27. Patel A., Geffner L., Vina R. Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: a prospective randomized study. J. Thorac. Cardiovasc. Surg. 2005; 130(6): 1631–1638.
  28. Charwat S., Lang I., Dettke M. et al. Effect of intramyocardial delivery of autologous bone marrow mononuclear stem cells on the regional myocardial perfusion. NOGA-guided subanalysis of the MYSTAR prospective randomised study. Thromb Haemost. 2010 Mar;103(3):564–71.
  29. Freyman T., Polin G., Osman H. et al. A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. European Heart Journal. 2006; 27:1114–1122.
  30. Fatkhudinov T.Kh., Slashcheva G.A., Bol’shakova G.B. i dr. Napravleniya migratsii mononuklearov kostnogo mozga pri intrakoronarnom transventrikulyarnom vvedenii. Kletochnye tekhnologii v biologii i meditsine. 2009; 4:222–228.
  31. Bartunek J., Wijns W., Heyndrickx G. et al. Timing of intracoronary bone-marrow-derived stem cell transplantation after ST-elevation myocardial infarction. Nature clinical practice cardiovascular medicine. 2006; 3: 52–56.
  32. Kumar V., Abbas A. et al. 7 ed. Pathologic Basis of Disease. Elsevier Inc. 2004: 1525.
  33. Souders C., Bowers S., Baudino T. Cardiac Fibroblast. The Renaissance Cell. Circ. Res. 2009;105:1164–1176.
  34. Sun Y., Weber K. Infarct scar: a dynamic tissue. Cardiovascular Research. 2000; 46: 250–256.
  35. Jugdutt B. Ventricular Remodeling After Infarction and the Extracellular Collagen Matrix. Circulation. 2003; 108: 1395–1403.
  36. Landa N., Miller L., Feinberg M. Effect of Injectable Alginate Implant on Cardiac Remodeling and Function After Recent and Old Infarcts in Rat. Circulation. 2008; 117: 1388–1396.
  37. Eglitis M., Mezey E. Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice. Proc. Nat. Acad. Sci. USA. 1997; 94: 4080–4085.
  38. Ferrari G., Cusella-DeAngelis G., Coletta M. et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science. 1998; 279: 1528–1530.
  39. Weissman I., Anderson D., Gage F. Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiation. Ann. Rev. Cell. Dev. Biol. 2001;17: 387–403.
  40. Prockop D., Kota D., Bazhanov N. et al. Evolving paradigms for repair of tissues by adult stem/progenitor cells (MSCs). J. Cell. Mol. Med. 2010; 14(9): 2190–2199.
  41. Lucas J., Terada N. Cell fusion and plasticity. Cytotechnology. 2003; 41: 103–109.
  42. Burchfield J., Dimmeler S. Role of paracrine factors in stem and progenitor cell mediated cardiac repair and tissue fibrosis. Fibrogenesis & Tissue Repair. 2008; 1(4): 1–11.
  43. Bochkov N.P. Kletochnaya terapiya v svete dokazatel’noi meditsiny. Klinicheskaya meditsina. 2006;10: 4–9.
  44. Yagudina R.I., Chibilyaev V.A. Ispol’zovanie konechnykh i surrogatnykh tochek v farmakoekonomicheskikh issledovaniyakh. Farmakoekonomika. 2010; 3(2): 12–18.
  45. Suzuki E., Hirata Y., Kohmoto O. et al. Cellular Mechanisms for Synthesis and Secretion of Atrial Natriuretic Peptide and Brain Natriuretic Peptide in Cultured Rat Atrial Cells. Circulation Research. 1992;71: 1039–1048.
  46. Rodriguez-Porcel M. In vivo imaging and monitoring of transplanted stem cells: clinical applications. Curr. Cardiol. Rep. 2010 Jan;12(1):51–8.

Дополнительные файлы

Доп. файлы
Действие
1. JATS XML
Скачать

© Издательство "Педиатръ", 2012



Данный сайт использует cookie-файлы

Продолжая использовать наш сайт, вы даете согласие на обработку файлов cookie, которые обеспечивают правильную работу сайта.

О куки-файлах