TOPICAL ISSUES OF FOOD ALLERGY DIAGNOSIS IN PEDIATRIC PRACTICE

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Abstract

Food allergy (FA) in children, especially in infancy, is still a significant public health problem. The severity and prognosis of disease progression associated with FA considerably depends on the correct and early diagnostics of this pathology, as well as on the following management of a child. At the same time delayed elimination diet administration, unreasonable or overlong dietary intervention might have become abuse management of a patient and have a negative impact on the development of a child and reduce the quality of life. The article summarizes the current practical approaches to the diagnosis of FA based on evidence-based medicine and adopted European and Russian national consensus documents, as well as on our own experience of management of patients with this pathology. FA diagnosis in a child usually includes clinical laboratory tests and clarification of clinical and anamnestic data. Unfortunately, it is a fact that preference is given to laboratory methods for diagnosis based on specific IgE determination or skin samples. However, the basis for cause-significant allergen identifying is detecting detailed medical history and clinical picture of a disease which still appears to be the most reliable tool for FA diagnosis.

 

About the authors

S. G. Makarova

Scientifi c Centre of Children Health, Moscow, Russian Federation
Sechenov First Moscow State Medical University, Russian Federation

Author for correspondence.
Email: sm27@yandex.ru
доктор медицинских наук, главный научный сотрудник отдела по клиническим исследованиям в педиатрии Научного центра здоровья детей, профессор кафедры аллергологии и клинической иммунологии педиатрического факультета Первого МГМУ им. И.М. Сеченова
Адрес: 119991, Москва, Ломоносовский пр-т, д. 2, стр. 1, тел.: +7 (499) 132-26-00 Россия

L. S. Namazova-Baranova

Scientifi c Centre of Children Health, Moscow, Russian Federation
Sechenov First Moscow State Medical University, Russian Federation
N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation

Email: namazova@nczd.ru
профессор, член-корреспондент РАН, заместитель директора — директор НИИ ППиВЛ Научного центра здоровья детей
Адрес: 119991, Москва, Ломоносовский пр-т, д. 2, стр. 1, тел.: +7 (495) 967-14-14 Россия

E. A. Vishneva

Scientifi c Centre of Children Health, Moscow, Russian Federation

Email: vishneva@nczd.ru
кандидат медицинских наук, завeдующая отделом стандартизации и клинической фармакологии Научного центра здоровья детей
Адрес: 119991, Москва, Ломоносовский пр-т, 2, стр. 1, тел.: +7 (499) 134-03-92 Россия

A. K. Gevorkyan

Scientifi c Centre of Children Health, Moscow, Russian Federation
Sechenov First Moscow State Medical University, Russian Federation

Email: gevorkyan@nczd.ru

кандидат медицинских наук, врач аллерголог-иммунолог, главный врач КДЦ НИИ ППиВЛ Научного центра здоровья детей, профессор кафедры аллергологии и клинической иммунологии педиатрического факультета Первого МГМУ им. И.М. Сеченова
Адрес: 119991, Москва, Ломоносовский пр-т, 2, стр. 1, тел.: +7 (499) 967-14-20

Россия

A. A. Alekseeva

Scientifi c Centre of Children Health, Moscow, Russian Federation
Sechenov First Moscow State Medical University, Russian Federation

Email: aleksaa06@yandex.ru
кандидат медицинских наук, педиатр, врач аллерголог-иммунолог, заведующая отделением ОВЛД с аллергическими болезнями и заболеваниями органов дыхания НИИ ППиВЛ, ассистент кафедры аллергологии и клинической иммунологии педиатрического факультета Первого МГМУ им. И.М. Сеченова Адрес: 119991, Москва, Ломоносовский пр-т, 2, стр. 1, тел.: +7 (499) 134-02-75 Россия

M. I. Petrovskaya

Scientifi c Centre of Children Health, Moscow, Russian Federation
Sechenov First Moscow State Medical University, Russian Federation

Email: petrovskaya_maria@mail.ru

аспирант кафедры аллергологии и клинической иммунологии педиатрического факультета Первого МГМУ им. И.М. Сеченова, врач аллерголог-иммунолог отделения диагностики и восстанови-тельного лечения Научного центра здоровья детей, младший научный сотрудник отдела стандартизации и клинической фармакологии Научного центра здоровья детей
Адрес: 119991, Москва, Ломоносовский пр-т, 2, стр. 1, тел.: +7 (495) 967-14-14

Россия

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