Methods of Molecular Transfusion in the Intensive Therapy of Critical States

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Abstract

Development of extracorporeal blood purification acquires greater significance in the intensive care of multiple organ failures (MOF) with all the pathophysiological aspects of its constituent parts. MOF are the main cause of mortality among critically ill patients and treatment of these patients require significant investment. The purpose of the implementation of extracorporeal blood correction techniques today is multiple organ support therapy (MOST). Early extracorporeal therapy is used only in the treatment of renal failure. Today extracorporeal techniques are increasingly being used to replace the functions of various organs and systems. MOST includes diffusion, convection, filtration, sorption, apheresis methodic. They affect the molecular and electrolyte composition of blood, allow to correct, repair, replace, and maintain homeostasis in severe multiorgan dysfunction. Extracorporeal new molecular technologies have been successfully applied in the intensive care of severe heart and respiratory failure, acute kidney injury and acute hepatic dysfunction, in the treatment of severe sepsis, metabolic disorders, the correction of immune imbalance.

About the authors

M. B. Yaroustovsky

Bakoulev Scientifi c Center for Cardiovascular Surgery, Moscow, Russian Federation

Author for correspondence.
Email: mbyar@yandex.ru

доктор медицинских наук, профессор, заведующий отделением гравитационной хирургии крови и эндоскопии ФГБУ НЦССХ Адрес: 121552, Москва, Рублевское шоссе, д. 135, тел.: +7 (495) 414-75-68

Россия

M. V. Abramyan

Bakoulev Scientifi c Center for Cardiovascular Surgery, Moscow, Russian Federation

Email: mar-abr@rambler.ru

кандидат медицинских наук, ведущий научный сотрудник отделения гравитационной хирургии крови и эндоскопии ФГБУ НЦССХ Адрес: 121552, Москва, Рублевское шоссе, д. 135, тел.: +7 (495) 414-75-03

Россия

N. P. Krotenko

Bakoulev Scientifi c Center for Cardiovascular Surgery, Moscow, Russian Federation

Email: npkrotenko@bakulev.ru

кандидат медицинских наук, врач-анестезиолог-реаниматолог отделения гравитационной хирургии крови и эндоскопии ФГБУ НЦССХ Адрес: 121552, Москва, Рублевское шоссе, д. 135, тел.: +7 (495) 414-75-02

E. V. Komardina

Bakoulev Scientifi c Center for Cardiovascular Surgery, Moscow, Russian Federation

Email: nesluchainost@mail.ru

младший научный сотрудник отделения гравитационной хирургии крови и эндоскопии ФГБУ НЦССХ Адрес: 121552, Москва, Рублевское шоссе, д. 135, тел.: +7 (495) 414-75-03

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