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Interstitial lung diseases (ILD, diffuse lung diseases) are a heterogeneous group of diseases in which a pathological process primarily involved alveoli and perialveolar interstitium, resulting in impaired gas exchange, restrictive changes of lung ventilation function and diffuse interstitial changes detectable by X-ray. Сhildren’s interstitial lung diseases is an topical problem of pediatric pulmonology. The article presents current information about classification, epidemiology, clinical presentation, diagnostics, treatment and prognosis of these rare diseases. The article describes the differences in the structure, pathogenesis, detection of various histological changes in children’s ILD compared with adult patients with ILD. Authors cite an instance of registers pediatric patients with ILD. The clinical semiotics of ILD, the possible results of objective research, the frequency of symptoms, the features of medical history, the changes detected on chest X-rays, CT semiotics described in detail. Particular attention was paid to interstitial lung diseases, occurring mainly in newborns and children during the first two years of life, such as  congenital deficiencies of surfactant proteins, neuroendocrine cell hyperplasia of infancy, pulmonary interstitial glycogenosis. The diagnostic program for children’s ILD, therapy options are presented in this article.


About the authors

E. V. Boitsova

I.P. Pavlov St. Petersburg State Medical University, Russian Federation

Author for correspondence.

доктор медицинских наук, руководитель лаборатории детской пульмонологии НИИ пульмонологии Санкт-Петербургского государственного медицинского университета им. акад. И.П. Павлова.
Адрес: 199111, Санкт-Петербург, ул. Рентгена, д. 12

Russian Federation

M. A. Belyashova

Peoples’ Friendship University of Russia, Moscow, Russian Federation


клинический ординатор, лаборант кафедры педиатрии Российского университета дружбы народов
Адрес:117198, Москва, ул. Миклухо-Маклая, д. 6, тел.: +7 (499) 236-11-52

Russian Federation

D. Yu. Ovsyannikov

Peoples’ Friendship University of Russia, Moscow, Russian Federation


доктор медицинских наук, заведующий кафедрой педиатрии Российского университета дружбы народов
Адрес:117198, Москва, ул. Миклухо-Маклая, д. 6, тел.: +7 (499) 236-11-52

Russian Federation


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