CHARACTERISTICS OF LEFT VENTRICULAR DIASTOLIC FUNCTION IN PATIENTS BEFORE AND AFTER CORONARY ARTERY BYPASS GRAFTING

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Abstract

Diastolic heart dysfunction occurs essentially in patients who suffer from chronic heart failure. In this context an investigation and application of different methods for diastolic function improvement remain a priority in the therapy of cardiovascular diseases. Objective: Our aim was to estimate coronary artery bypass grafting effect on the left ventricular functionality in patients with coronary heart disease. Methods: Patients (30 men without myocardial infarction and 44 — with myocardial infarction) were investigated by Doppler Echocardiography before and after coronary artery bypass grafting for left ventricular diastolic function assessment. In addition, during the year after operation examinations were carried out. Analysis of the data allowed detecting two types of disorders of transmitral flow: rigid and pseudonormal. Results: Our investigation showed that transmitral parameters improved in patients after operation. Patients without myocardial infarction in anamnesis had a myocardium cell relaxation improvement (IVRT decreasing; p =0,046), but an active myocardium relaxation turned for the better (increasing of Е/А (p <0,001) by component А lowering (p =0,003). Changes of pulmonary veins parameters were followed by the improvement of left heart ventricle relaxation: active — PVD decreasing, p =0,051; and passive — PVА decreasing, p =0,028. Patients with myocardial infarction in anamnesis had an IVRT decreasing (p =0,040) and А decreasing (p =0,041). In addition, in this group left atrial function improved (PVS decreasing; p =0,037). Conclusion: Coronary artery bypass grafting is effective in left ventricular diastolic function improvement and Doppler Echocardiography method can become an important criterion to estimate the treatment adequacy.

 

 

About the authors

I. A. Khlopina

Northern State Medical University, Arkhangelsk, Russian Federation

Author for correspondence.
Email: hlopina@yandex.ru

кандидат медицинских наук, доцент, заведующая кафедрой пропедевтики внутренних
болезней СГМУ
Адрес: 163061, Архангельск, Троицкий пр-т, д. 51, тел.: +7 (8182) 62-60-35

Russian Federation

E. N. Shatsova

Northern State Medical University, Arkhangelsk, Russian Federation

Email: hlopina@yandex.ru

доктор медицинских наук, профессор кафедры поликлинической терапии и сестрин-
ского дела СГМУ
Адрес: 163061, Архангельск, Троицкий пр-т, д. 51, тел.: +7 (8182) 28-57-56

Russian Federation

V. V. Lupachev

Northern State Medical University, Arkhangelsk, Russian Federation
M.V. Lomonosov Northern (Arctic) Federal University, Arkhangelsk, Russian Federation

Email: valerii-lvv@mail.ru

доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней
СГМУ, профессор Института комплексной безопасности САФУ им. М.В. Ломоносова
Адрес: 163061, Архангельск, Троицкий пр-т, д. 51, тел.: +7 (8182) 62-60-35

Russian Federation

A. N. Pakuev

Northern State Medical University, Arkhangelsk, Russian Federation

Email: plakuev@rambler.ru

кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней
СГМУ
Адрес: 163061, Архангельск, Троицкий пр-т, д. 51, тел.: +7 (8182) 62-60-35

Russian Federation

A. V. Chernozemova

Clinical Hospital of Healthcare Ministry, Arkhangelsk, Russian Federation

Email: hlopina@yandex.ru

кандидат медицинских наук, заместитель главного врача по поликлинической
работе 1-й ГКБ им. Е.Е. Волосевич
Адрес: 163061, Архангельск, ул. Гайдара, д. 3, тел.: +7 (8182) 62-60-35

Russian Federation

R. V. Kubasov

Northern State Medical University, Arkhangelsk, Russian Federation

Email: romanas2001@gmail.com

кандидат биологических наук, доцент кафедры мобилизационной подготовки здравоох-
ранения и медицины катастроф СГМУ
Адрес: 163061, Архангельск, Троицкий пр-т, д. 51, тел.: +7 (8182) 24-22-65

Russian Federation

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