Contemporary Interpretations of Ophthalmological Manifestations of Chronic Myeloproliferative Neoplasms
- Authors: Moshetova L.K.1, Egoryan L.B.1,2, Vinogradova O.J.3,4,5, Turkina K.I.1,2, Shikhbabaeva D.I.4
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Affiliations:
- Russian Medical Academy of Continuous Professional Education
- Moscow Ophthalmology Center of Botkin City Clinical Hospital
- Pirogov Russian National Research Medical University
- Moscow Hematology Center of Botkin City Clinical Hospital
- Rogachev National Medical Research Center for Pediatric Hematology
- Issue: Vol 78, No 3 (2023)
- Pages: 208-212
- Section: OPHTHALMOLOGY: CURRENT ISSUES
- URL: https://vestnikramn.spr-journal.ru/jour/article/view/2277
- DOI: https://doi.org/10.15690/vramn2277
- ID: 2277
Cite item
Abstract
The course of chronic myeloproliferative neoplasms (CMPN), a group of systemic hematological diseases, can be accompanied by various complications and changes in tissues and organs of the whole organism. The eye is the only organ where damage of nerve fibers and blood vessels can be directly observed and examined, and ocular symptoms can be the initial, manifest of systemic pathology, the toxic effects of modern targeted therapy, or the first manifestation of a relapse of the disease after treatment. The most frequently described manifestations are caused by hematological anomalies that cause microvascular disorders. Such changes today remain insufficiently studied in terms of the using new research methods and contemporary targeted therapy. In addition, ocular symptoms may precede more serious extraocular complications. Combined ophthalmological and hematological examination of patients with CMPN can become a preventive approach for early diagnosis and timely treatment.
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About the authors
Larisa K. Moshetova
Russian Medical Academy of Continuous Professional Education
Author for correspondence.
Email: moshetovalk@yandex.ru
ORCID iD: 0000-0002-5899-2714
SPIN-code: 5697-6825
MD, PhD, Professor, Academician of the RAS
Russian Federation, MoscowLidia B. Egoryan
Russian Medical Academy of Continuous Professional Education; Moscow Ophthalmology Center of Botkin City Clinical Hospital
Email: legoryan@yandex.ru
ORCID iD: 0000-0001-8077-5225
SPIN-code: 9437-9184
PhD Student
Russian Federation, Moscow; MoscowOlga J. Vinogradova
Pirogov Russian National Research Medical University; Moscow Hematology Center of Botkin City Clinical Hospital; Rogachev National Medical Research Center for Pediatric Hematology
Email: olgavinz@mail.ru
ORCID iD: 0000-0002-3669-0141
SPIN-code: 7195-5351
MD, PhD, Professor
Russian Federation, Moscow; Moscow; MoscowKsenia I. Turkina
Russian Medical Academy of Continuous Professional Education; Moscow Ophthalmology Center of Botkin City Clinical Hospital
Email: kseniyait@mail.ru
ORCID iD: 0000-0002-4989-7467
SPIN-code: 3187-4280
MD, PhD
Russian Federation, Moscow; MoscowDgariat I. Shikhbabaeva
Moscow Hematology Center of Botkin City Clinical Hospital
Email: d.shikhbabaeva@yandex.ru
ORCID iD: 0000-0002-1384-1621
SPIN-code: 6023-3313
MD, PhD
Russian Federation, MoscowReferences
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