PROTEOMICS AS A FUNDAMENTAL TOOL FOR SUBCLINICAL SCREENING, TESTS VERIFICATION AND ASSESSMENT OF APPLIED THERAPY

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Abstract

Proteomics is a science which studies proteins of the body, interactions of proteins and their biological functions. Today, it is an essential partner in establishing preclinical diagnosis protocols. In conjunction with other sciences such as genomics and bioinformatics it will be possible to diagnose diseases on the earliest stages before its clinical onset or to gain the dynamics of pathological processes in the body and response to drug therapy. This article discusses general aspects of proteomics as well as special ones on the basis of models of cardiac diseases and cancer.

 

About the authors

S. V. Suchkov

I.M. Sechenov First Moscow State Medical University, Russian Federation
A.I. Evdokimov Moscow State Medical Dental University, Russian Federation

Author for correspondence.
Email: ssuchkov57@gmail.com

PhD, Professor of Department of A.I. Evdokimov Clinical Immunology, Professor of Department of Pathology I.M. Sechenov First Moscow State Medical University
Address: 101000, Moscow, Miasnitskaya St., 20; tel.: (495) 771-32-32; fax: (495) 708-31-56

Russian Federation

D. S. Kostushev

A.I. Evdokimov Moscow State Medical Stomatological University Moscow, Russian Federation

Email: dkostushev@gmail.com

Intern Researcher of Department of Pathology I.M. Sechenov First Moscow State Medical University
Address: 119991, Moscow, Trubetskaya St., 8/2; tel.: (425) 037-08-54

Russian Federation

S. A. Krynskii

I.M. Sechenov First Moscow State Medical University, Russian Federation

Email: dkostushev@gmail.com

First Moscow State Medical University Student
Address: 119991, Moscow, Trubetskaya St., 8/2; tel.: (425) 037-08-54

Russian Federation

D. A. Gnatenko

A.I. Evdokimov Moscow State Medical Stomatological University Moscow, Russian Federation

Email: gnatenkodmitrii@gmail.com
Intern Researcher of Department of Pathology I.M. Sechenov First Moscow State Medical University
Address: 119991, Moscow, Trubetskaya St., 8/2 Russian Federation

M. A. Pal'tsev

National Research Centre «Kurchatov Institute», Moscow, Russian Federation

Email: paltsev_ma@rrcki.ru

PhD, the Academician of the Russian Academy of Medical Sciences, Professor, Deputy Director for Science of Research Center «Kurchatov Institute» Address: 123182, Moscow, Academician Kurchatov Square, 1; tel.: (499) 196-95-39; fax: (499) 196-17- 04;
e-mail: paltsev_ma@rrcki.ru

Russian Federation

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