Immune Landscape Characteristics in Endometriosis
- Authors: Patsap O.I.1, Khabarova M.B.2, Buyanova A.A.3, Mikhalev S.A.3, Atyakshin D.A.1, Babkina A.V.4, Mikhaleva L.M.5
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Affiliations:
- Peoples’ Friendship University of Russia
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- Pirogov Russian National Research Medical University
- City Clinical Oncological Hospital No. 1
- B.V. Petrovsky Russian Scientific Center of Surgery
- Issue: Vol 78, No 1 (2023)
- Pages: 5-10
- Section: OBSTETRICS AND GYNAECOLOGY: CURRENT ISSUES
- URL: https://vestnikramn.spr-journal.ru/jour/article/view/2259
- DOI: https://doi.org/10.15690/vramn2259
Cite item
Abstract
This review is devoted to endometriosis-associated immune cells and immune molecules, analysis of various databases, new insights, theories, biomarkers, reviews of research in this area. To date, many attempts have been made to establish a certain role of immune cells and the microenvironment in the development of endometriosis. Nevertheless, despite intensive studies of endometriosis, the role of inflammatory cells and molecules has not yet been fully studied. As we know, the pathobiology of endometriosis is not fully understood, and its progression is associated with a local and systemic inflammatory reaction. It is important to clarify the role of the immune system to better understand its significance in the pathogenesis of endometriosis, especially in the case of atypical and endometriosis-associated ovarian tumors. The above requires further study of this problem in order to optimize the pathogenetically justified modern therapy of endometriosis.
Keywords
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About the authors
Olga I. Patsap
Peoples’ Friendship University of Russia
Email: Cleosnake@yandex.ru
ORCID iD: 0000-0003-4620-3922
SPIN-code: 6460-1758
МD, PhD
Russian Federation, MoscowMarina B. Khabarova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: khabarovaMB@yandex.ru
ORCID iD: 0000-0003-3526-0366
МD, PhD
Russian Federation, MoscowAnastasiia A. Buyanova
Pirogov Russian National Research Medical University
Email: anastasiiabuianova97@gmail.com
SPIN-code: 5725-7792
Scopus Author ID: 57218589485
ResearcherId: AGU-7781-2022
Laboratory Assistant
Russian Federation, MoscowSergey A. Mikhalev
Pirogov Russian National Research Medical University
Email: mikhalev@me.com
ORCID iD: 0000-0002-4822-0956
SPIN-code: 8105-7908
МD, PhD
Russian Federation, MoscowDmitriy A. Atyakshin
Peoples’ Friendship University of Russia
Email: atyakshin-da@rudn.ru
ORCID iD: 0000-0002-8347-4556
SPIN-code: 3830-8152
МD, PhD
Russian Federation, MoscowAlexandra V. Babkina
City Clinical Oncological Hospital No. 1
Email: nikanorovaalex@gmail.com
ORCID iD: 0000-0001-5485-5803
SPIN-code: 3815-4541
MD
Russian Federation, MoscowLiudmila M. Mikhaleva
B.V. Petrovsky Russian Scientific Center of Surgery
Author for correspondence.
Email: mikhalevalm@yandex.ru
ORCID iD: 0000-0003-2052-914X
SPIN-code: 2086-7513
МD, PhD, Professor, Corresponding Member of the RAS
Russian Federation, MoscowReferences
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