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Nowadays the structure of acute intestinal infections pathogens changed substantially. It is caused by constant evolution of bacteria and involvement of the opportunistic pathogens in the pathological processes. The aim of the study was to investigate the prevalence of the acute intestinal infections caused by staphylococci in the North-Eastern region of Ukraine, to determine the pathogenic factors in isolated pathogens. The materials for the study were the data of statistical reporting of Sumy regional sanitary-epidemiological station. Biological properties of the 50 Staphylococcus aureus strains were investigated. In the work used The descriptive and analytical techniques of the epidemiological, bacteriological and statistical methods were used. In the 2007–2012 the incidence of acute intestinal infections caused by staphylococci was in the range 17,1–20,3 on the 100 thousand. 2 year-old children were prevailed in the age structure. The largest numbers of cases were recorded in January, February, April, June and August. Strains of Staphylococcus aureus, isolated from the patients were characterized by a wide spectrum of pathogenic and persistence factors. Anti-lisozym activity was in 100% of the investigated cultures, anti-interferon and anti-complement activity were detected in 96,0 and 64,0% stains, ability to adhesion was present in 36,0% stains. At the same time anti-lisozym, anti-interferon and anti-complement activity were showed in the 52,0% stains of the Staphylococcus aureus. These data characterize negatively predicted for the near future regional trends in morbidity.

About the authors

V. N. Golubnichaya

Sumy State University, Sumy, Ukraine

Author for correspondence.
Email: golubnichiy@ukr.net
MD, associate professor of the Department Hygiene and Ecology of Microbiology, Virology and Immunology of Sumy State University Ukraine

N. G. Malysh

Sumy State University, Sumy, Ukraine

Email: ninamalysh@mail.ru
MD, assistant of the Department of Infection Disease with Epidemiology of Sumy State University Ukraine


  1. Malyi V.P. General characteristics of acute intestinal infections. Klinicheskaya immunologiya allergologiya infektologiya = Clinical immunology, allergology, infectology. 2010; 7 (36): 14–32.
  2. Moskalyuk V.D., Bogachik N.A., Venglovs'ka Ya.V., Golyar O.І. Features of the differential diagnosis of acute intestinal infections (review). Bukovinskii meditsinskii vestnik = Bukovina Medical Journal. 2009; 13 (1): 122–128.
  3. Vozianova Zh.I. Diarrheagenic Escherichia coli. Sovremennye infektsii = Modern infection. 2008; 3: 4–9.
  4. Podkolzin A.T., Fenske E.B., Abramycheva N.Yu. Season and age related structure of acute intestinal infections morbidity in the Russian Federation. Terapevticheskii arkhiv = Therapeutic Archives. 2007; 79 (11): 10–16.
  5. Mikhailova L.V. The role of conditionally pathogenic microorganisms in the structure morbidity of acute intestinal infections under conditions of large industrial city. Vestn. RGMU = Bulletin of the Russian State Medical University. 2008; 2 (61): 314.
  6. Chemurzieva N.V. Sovershenstvovanie laboratornoi diagnostiki infektsionnykh protsessov, assotsiirovannykh s uslovno-patogennymi mikroorganizmami, s ispol'zovaniem komp'yuternykh tekhnologii. Avtoref. diss. … kand. biol. nauk [Improvement of laboratory diagnosis of infectious processes associated with opportunistic microorganisms using of computer technologies. Abstract for Dissertation for the degree of Candidate of biological science]. Perm. 2008. 16 p.
  7. Mikhailova L.V., Kramar' V.O., Savchenko T.N., Klimova T.N. Factors contributing to the persistence conditionally pathogenic microorganisms. Vestn. VolGMU = Bulletin of the Volgograd State Medical University. 2010; 4 (36): 76–79.
  8. Gabidullin Z.G., Akhtarieva A.A., Tuigunov M.M. i dr. Pathogenicity factors of bacteria of the Enterobacteriaceae family, providing survival in host organism. Meditsinskii vestnik Bashkortostana = Bashkortostan Medical Journal. 2009; 4 (5): 86–94.
  9. Zueva L.P., Yafaev R.Kh. Epidemiologiya [Epidemiology]. Saint Petersburg: Foliant. 2005. 748 p.
  10. Prikaz MZ SSSR ot 22.04.85 g. № 535 «Ob unifikatsii mikrobiologicheskikh (bakteriologicheskikh) metodov issledovaniya, primenyaemykh v kliniko-diagnosticheskikh laboratoriyakh lechebno-profilakticheskikh uchrezhdenii» [Order of the Ministry of Health of the USSR of 04.22.85, № 535 “On the unification of microbiological (bacteriological) research methods used in clinical diagnostic laboratories of medical institutions”]. Moscow. 1985. 126 p.
  11. Brilis V.I., Brilis T.A., Lantsner Kh.G., Lantsner A.A. Method for studying adhesion process of microorganisms. Laboratornoe delo = Laboratory work. 1986; 4: 210–212.
  12. Metod. rekomendats. Departamenta gossanepidnadzora Minzdrava RF «Diagnostika i sanatsiya stafilokokkovykh bakterionositelei» [Methodical recommendations of the Department of Sanitary Inspection in the Ministry of Health of the Russian Federation "Diagnosis and treatment of staphylococcal bacteria carriers"]. Мoscow. 2001. 14 p.
  13. Bukharin O.V., Usvyatsov B.Ya., Malyshkin A.P., Nemtseva N.V. Method for determination of antilysozyme activity of microorganisms. Zhurnal mikrobiologii epidemiologii i immunologii = Journal of microbiology, epidemiology, and immunology. 1984; 2: 27–28.
  14. Savilov E.D., Astaf'ev V.A., Zhdanova S.N. Epidemiologicheskii analiz. Metody statisticheskoi obrabotki materiala [Epidemiological analysis. Methods of statistical analysis]. Novosibirsk: Nauka-Tsentr. 2011.
  15. Beloborodov V.B., Mitrokhin S.D. Staphylococcal infections. Infektsii i antimikrobnaya terapiya = Infection and Antimicrobial Therapy. 2003; 5 (1): 31–38.

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