A Single-Stage Population-Based Study of the Relationship between Cognitive and Somatic Health Parameters in Children of Secondary School Age

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Abstract

Background. One of the four important components of the formation of cognitive functions is somatic health. But to date, there are no population studies that consider the relationship with cognitive functions and school performance of a large range of somatic factors, which allows us to compare the strength of their hypothetical contribution to cognitive functioning with each other. This study is the second part of a population-based study, the first part of which is presented in the previous publication "A Single-Stage Population-Based Study of the Prevalence of Mild Cognitive Impairment in Children of Secondary School Age". Aims — to determine the main patterns in the relationship between cognitive-academic and somatic factors in a cohort of Russian children, 5th grade students at school. Methods. In Russian schoolchildren of the 5th grades of municipalities representing cities of all federal districts of the Russian Federation, the links with integrative cognitive success, the number of subtests performed at the level of mild cognitive impairment, the results of individual cognitive subtests, academic performance and the leading hand factor were analyzed — the following somatic factors: the presence of skin pathology, bronchial asthma, orthopedic, ophthalmological disorders, visual acuity, body mass index, parameters of the study of the function of external respiration, electrocardiography, ultrasound examination of the thyroid gland, laboratory blood tests. Results. The results of the survey of 1036 participants, 51% of them girls, were admitted to the analysis. It has been established that iron content is directly related to integrative cognitive success and school performance, the relationship is especially strong between subgroups of iron content above and below 26.4 mmol/l. Clinical levels of erythrocytes are more strongly associated with integrative cognitive success and individual cognitive functions than other factors: in erythropenia cognitive parameters are worse. The presence of thyroid cysts directly correlates with some of the worst parameters of cognitive activity. High body mass index and low hemoglobin are associated with poorer academic performance. Conclusions. The results of the study for the first time on a cohort of Russian schoolchildren showed a connection with cognitive activity and school performance of a number of somatic factors, including iron content, which requires further in-depth study.

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About the authors

George A. Karkashadze

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Author for correspondence.
Email: karkga@mail.ru
ORCID iD: 0000-0002-8540-3858
SPIN-code: 6248-0970

MD, PhD

Russian Federation, Moscow

Elena V. Kaitukova

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University (Pirogov Medical University)

Email: sunrise_ok@mail.ru
ORCID iD: 0000-0002-8936-3590
SPIN-code: 1272-7036

MD, PhD

Russian Federation, Moscow; Moscow

Tinatin Y. Gogberashvili

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Email: tinatina2004@mail.ru
ORCID iD: 0000-0001-9790-7490
SPIN-code: 5723-4805

PhD of Psychological Sciences

Russian Federation, Moscow

Tatiana A. Konstantinidi

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Email: tkonstantinidi@list.ru
SPIN-code: 7971-2040

MD, PhD

Russian Federation, Moscow

Olga B. Gordeeva

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University (Pirogov Medical University)

Email: obr@yandex.ru
ORCID iD: 0000-0001-8311-9506
SPIN-code: 2562-7725

MD, PhD

Russian Federation, Moscow; Moscow

Aishat M. Gazalieva

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Email: a.m.gazalieva@gmail.com
ORCID iD: 0009-0000-0293-1771
SPIN-code: 5540-7933

MD, PhD

Russian Federation, Moscow

Margarita A. Soloshenko

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Email: margosoloshenko@mail.ru
ORCID iD: 0000-0002-6150-0880
SPIN-code: 2954-9873

MD, PhD

Russian Federation, Moscow

Svetlana E. Kondratova

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Email: svetlana26.03@mail.ru
ORCID iD: 0000-0002-6522-5310
SPIN-code: 9095-2169
Russian Federation, Moscow

Eka A. Abashidze

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Email: 2803abashidze@mail.ru
ORCID iD: 0000-0002-5366-894X
SPIN-code: 6471-9838

MD, PhD

Russian Federation, Moscow

Grigory V. Revunenkov

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery

Email: rgv07@mail.ru
ORCID iD: 0000-0001-7834-213X
SPIN-code: 9754-3642

MD, PhD

Russian Federation, Moscow

Elena V. Komarova

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University (Pirogov Medical University)

Email: dr.klv@rambler.ru
ORCID iD: 0000-0001-6000-5418
SPIN-code: 2581-8021

MD, PhD

Russian Federation, Moscow; Moscow

Marika I. Ivardava

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University (Pirogov Medical University)

Email: makussa@mail.ru
ORCID iD: 0000-0002-4669-9510
SPIN-code: 4865-4688

MD, PhD

Russian Federation, Moscow; Moscow

Oksana M. Drapkina

National Medical Research Center for Therapy and Preventive Medicine

Email: ODrapkina@gnicpm.ru
ORCID iD: 0000-0002-4453-8430
SPIN-code: 4456-1297

MD, PhD, Professor, Academician of the RAS

Russian Federation, Moscow

Ruslan N. Shepel

National Medical Research Center for Therapy and Preventive Medicine

Email: r.n.shepel@mail.ru
ORCID iD: 0000-0002-8984-9056
SPIN-code: 3115-0515

MD, PhD

Russian Federation, Moscow

Kazbek S. Mezhidov

National Medical Research Center for Therapy and Preventive Medicine

Email: kmezhidov@mail.ru
ORCID iD: 0000-0002-6032-6286
SPIN-code: 6906-6680

MD, PhD

Russian Federation, Moscow

Leyla S. Namazova-Baranova

Research Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University (Pirogov Medical University)

Email: leyla.s.namazova@gmail.com
ORCID iD: 0000-0002-2209-7531
SPIN-code: 1312-2147

MD, PhD, Professor, Academician of the RAS

Russian Federation, Moscow; Moscow

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2. Fig.1. Relationship between iron content and belonging to a cognitive cluster: 0 - more successful, 1 - less successful cognitive clusters

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