THE STUDY OF MATURATION OF THE AUDITORY ANALYZER RABBIT ACCORDING DISTORTION-PRODUCT OTOACOUSTIC EMISSIONS

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Abstract


Aim: In our chronic experiment to  register changes of acoustic response of Distortion-Product Otoacoustic Emissions (DPOAE) of intact rabbits in postnatal ontogenesis for the purpose of getting normative data which can be used for studying impact of pathological factors on auditory function and maturation of activity of outer hair cell in ontogenesis. Materials and methods: Study of otoacoustic emissions used mature chinchilla rabbits with a 19 day life of up to 3 months. Results: in the course of ripening were obtained functional activity of outer hair cells of the cochlea. Conclusion: normative data obtained allow us to study using a rabbit model, the pathological effects of agents on the maturation of the outer hair cells of the cochlea in the experiment.


About the authors

I. N. D'yakonova

Russian National Research Medical University n.a. N.I. Pirogov, Moscow, Russian Federation

Author for correspondence.
Email: i-dyak@mail.ru

Russian Federation PhD, professor of the Department of Physiology of Medico-Biological Faculty of N.I. Pirogov RRMU. Address: 1, Ostrovityanov Street, Moscow, RF, 117997, tel.: +7 (495) 434-83-00

Yu. S. Ishanova

Russian National Research Medical University n.a. N.I. Pirogov, Moscow, Russian Federation

Email: ishanova@hotmail.com

Russian Federation MD, senior research scientist of the Laboratory for Scientific Research of Clinical and Experimental Pediatric Otolaryngology of N.I. Pirogov RRMU. Address: 1, Ostrovityanov Street, Moscow, RF, 117997, tel.: +7 (499) 236-45-38

I. V. Rakhmanova

Russian National Research Medical University n.a. N.I. Pirogov, Moscow, Russian Federation

Email: ishanova@hotmail.com

Russian Federation PhD, Head of the Laboratory for Scientific Research of Clinical and Experimental Pediatric Otolaryngology of N.I. Pirogov RRMU. Address: 1, Ostrovityanov Street, Moscow, RF, 117997, tel.: +7 (499) 236-45-38

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