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THE STUDY OF MATURATION OF THE AUDITORY ANALYZER RABBIT ACCORDING DISTORTION-PRODUCT OTOACOUSTIC EMISSIONS
- Authors: D'yakonova I.N.1, Ishanova Y.S.1, Rakhmanova I.V.1
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Affiliations:
- Russian National Research Medical University n.a. N.I. Pirogov, Moscow, Russian Federation
- Issue: Vol 68, No 11 (2013)
- Pages: 94-97
- Section: SHORT MESSAGES
- URL: https://vestnikramn.spr-journal.ru/jour/article/view/128
- DOI: https://doi.org/10.15690/vramn.v68i11.849
- ID: 128
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Abstract
Aim: In our chronic experiment to register changes of acoustic response of Distortion-Product Otoacoustic Emissions (DPOAE) of intact rabbits in postnatal ontogenesis for the purpose of getting normative data which can be used for studying impact of pathological factors on auditory function and maturation of activity of outer hair cell in ontogenesis. Materials and methods: Study of otoacoustic emissions used mature chinchilla rabbits with a 19 day life of up to 3 months. Results: in the course of ripening were obtained functional activity of outer hair cells of the cochlea. Conclusion: normative data obtained allow us to study using a rabbit model, the pathological effects of agents on the maturation of the outer hair cells of the cochlea in the experiment.
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About the authors
I. N. D'yakonova
Russian National Research Medical University n.a. N.I. Pirogov, Moscow, Russian Federation
Author for correspondence.
Email: i-dyak@mail.ru
PhD, professor of the Department of Physiology of Medico-Biological Faculty of N.I. Pirogov RRMU. Address: 1, Ostrovityanov Street, Moscow, RF, 117997, tel.: +7 (495) 434-83-00 Russian Federation
Yu. S. Ishanova
Russian National Research Medical University n.a. N.I. Pirogov, Moscow, Russian Federation
Email: ishanova@hotmail.com
MD, senior research scientist of the Laboratory for Scientific Research of Clinical and Experimental Pediatric Otolaryngology of N.I. Pirogov RRMU. Address: 1, Ostrovityanov Street, Moscow, RF, 117997, tel.: +7 (499) 236-45-38 Russian Federation
I. V. Rakhmanova
Russian National Research Medical University n.a. N.I. Pirogov, Moscow, Russian Federation
Email: ishanova@hotmail.com
PhD, Head of the Laboratory for Scientific Research of Clinical and Experimental Pediatric Otolaryngology of N.I. Pirogov RRMU. Address: 1, Ostrovityanov Street, Moscow, RF, 117997, tel.: +7 (499) 236-45-38 Russian Federation
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