Diabetes Mellitus and Thyroid Dysfunction, Including Autoimmune Genesis. Mutual Influence of Pathologies

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Abstract


Thyroid disease, including autoimmune genesis, and diabetes mellitus are the two most common endocrine diseases in clinical practice. These pathologies have a mutual influence on each other. On the one hand, thyroid hormones are involved in regulation of carbohydrate metabolism: excessive production of thyroid hormones is associated with hyperglycemia, while hypothyroidism has a decreased level of glucose production by the liver. On the other hand, glucose homeostasis disorder affects the functional state of the thyroid gland: dystrophic, sclerotic and atrophic processes are developing in thyroid gland, what is a manifestation of diabetic microangiopathy. This article demonstrates the need to take into account the mutual influence of pathologies for optimal treatment of this conditions.


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About the authors

A. V. Tkachuk

Endocrinology Research Centre

Author for correspondence.
Email: arinatarasova@inbox.ru
ORCID iD: 0000-0001-5917-6869
SPIN-code: 8825-8874

Russian Federation, Moscow

MD, Clinical Resident

M. S. Mikhina

Endocrinology Research Centre

Email: docmikhina@mail.ru
ORCID iD: 0000-0002-4382-0514
SPIN-code: 3172-5538

Russian Federation, Moscow

MD, Research Associate

L. I. Ibragimova

Endocrinology Research Centre

Email: ibragimovaliudmila@gmail.com
ORCID iD: 0000-0003-3535-520X
SPIN-code: 5013-8222

Russian Federation, Moscow

MD, PhD, Leading Research Associate

T. V. Nikonova

Endocrinology Research Centre

Email: tatiana_nikonova@mail.ru
ORCID iD: 0000-0001-5656-2596
SPIN-code: 8863-0201

Russian Federation, Moscow

MD, PhD

E. A. Troshina

Endocrinology Research Centre

Email: troshina@inbox.ru
ORCID iD: 0000-0002-8520-8702
SPIN-code: 8821-8990

Russian Federation, Moscow

MD, PhD, Professor, Corresponding Member of the RAS

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