КЛЕТОЧНАЯ ТЕРАПИЯ КРИТИЧЕСКОЙ ИШЕМИИ НИЖНИХ КОНЕЧНОСТЕЙ (ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ)

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Аннотация

Критическая ишемия нижних конечностей — синдром ряда различных по этиологии и патогенезу заболеваний периферических артерий. Критическая ишемия нижних конечностей характеризуется неблагоприятным прогнозом, высоким уровнем инвалидизации и смертности. Возможности хирургической и консервативной терапии критической ишемии нижних конечностей практически полностью исчерпаны. Определенные надежды возникли в связи с достижениями в области клеточных технологий. В статье представлен критический анализ патогенетических предпосылок применения стволовых/прогениторных клеток для лечения пациентов с критической ишемией нижних конечностей, подробно рассмотрены основные результаты доклинических и клинических исследований безопасности и эффективности клеточных технологий, перспективы их практического внедрения в клиническую практику, а также сформулированы нерешенные вопросы.

 

Об авторах

С. В. Лебедев

Медицинский центр Банка России, Москва, Российская Федерация

Автор, ответственный за переписку.
Email: lebedsv@mail.ru
кандидат медицинских наук, старший научный сотрудник, врач Центра доказательной медицинской практики и инновационных технологий стационара Медицинского центра Банка России Адрес: 117593, Москва, Севастопольский проспект, д. 66; тел.: (495) 676-80-50 Россия

А. В. Карасев

Медицинский центр Банка России, Москва, Российская Федерация

Email: stemcell@inbox.ru
заведующий отделением молекулярно-клеточных технологий Медицинского центра Банка России Адрес: 117593, Москва, Севастопольский проспект, д. 66; тел.: (495) 676-80-50 Россия

В. В. Кунгурцев

Медицинский центр Банка России, Москва, Российская Федерация

Email: kung-vadim@yandex.ru
доктор медицинских наук, профессор, сердечно-сосудистый хирург Медицинского центра Банка России Адрес: 117593, Москва, Севастопольский проспект, д. 66; тел.: (495) 676-83-16 Россия

А. В. Лохонина

Медицинский центр Банка России, Москва, Российская Федерация

Email: anastasia.cell@gmail.com
биолог Центра доказательной медицинской практики и инновационных техно- логий стационара Медицинского центра Банка России Адрес: 117593, Москва, Севастопольский проспект, д. 66; тел.: (495) 676-83-74 Россия

Е. Б. Клейменова

Медицинский центр Банка России, Москва, Российская Федерация

Email: stemcell@inbox.ru
доктор медицинских наук, заведующая Центром доказательной медицинской прак- тики и инновационных технологий стационара Медицинского центра Банка России Адрес: 117593, Москва, Севастопольский проспект, д. 66; тел.: (495) 676-80-11 Россия

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