ОСОБЕННОСТИ ФУНКЦИОНИРОВАНИЯ ЩИТОВИДНОЙ ЖЕЛЕЗЫ У ЛИЦ С ВИЧ-ИНФЕКЦИЕЙ

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Аннотация

В статье проведен анализ современных литературных данных, посвященных особенностям функционирования щитовидной железы у лиц с ВИЧ-инфекцией, рассмотрены структура нарушений тиреоидной функции у ВИЧ – инфицированных и механизмы патогенеза этих нарушений. В структуре нарушений функции щитовидной железы преобладают гипотиреоз, эутиреоидный патологический синдром, болезнь Грейвса, для которых оппортунистические инфекции являются триггерами иммунной активации. Отмечено, что стадия синдрома приобретенного иммунодефицита сопровождается развитием воспалительных и неопластических процессов в щитовидной железе. Убедительно доказано негативное влияние высокоактивной антиретровирусной терапии у ВИЧ-инфицированных на развитие тиреоидной дисфункции, в связи с чем показана целесообразность формирования групп риска и своевременная коррекция прогнозируемых заболеваний щитовидной железы.

 

Об авторах

Е. В. Тимофеева

Научный центр проблем здоровья семьи и репродукции человека СО РАМН, Иркутск, Российская Федерация

Автор, ответственный за переписку.
Email: eve_gin@list.ru
PG student of the Federal State Budgetary Institution “Scientific Centre of the Family Health and Human Reproduction Problems” under the Siberian Branch of RAMS. Address: 16, Timiryazeva St., Irkutsk, 664003, tel.: (3952) 20-76-36 Россия

О. Я. Лещенко

Научный центр проблем здоровья семьи и репродукции человека СО РАМН, Иркутск, Российская Федерация

Email: loyairk@mail.ru
PhD, Head of the socially significant infections laboratory of the Federal State Budgetary Institution “Scientific Centre of the Family Health and Human Reproduction Problems” under the Siberian Branch of RAMS. Address: 16, Timiryazeva St., Irkutsk, 664003, tel.: (3952) 20-76-36 Россия

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