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A combination of periodontitis and pulp or periapical tissues inflammation in one tooth is known as endo-periodontal lesions. Such kind of lesion is serious problem of modern dentistry. It was found that pathogenic microflora of periodontal pocket and root canal of tooth with eno-perio lesion is almost the equal and consist of anaerobic microorganisms. Pathogenic effects have not only microorganisms but also their life products. Apical foramen, lateral and additional canals are physiological ways for pathogens migration. Inflammatory processes in these structures complicate each other. Lack of information among dentists about treatment possibilities of endo-perio lesions is a main reasons of extraction such kind of teeth. Simultaneous elimination of pathogens both from periodontal pocket and root canal is a key factor for effective treatment. Periodontal status is main factor for prognosis of tooth with endo-perio lesion, because of it treatment of endo-perio lesions should consist of two stages: infection elimination and regeneration of tooth-supported structures.


About the authors

A. I. Grudyanov

Central research institute of dental and maxillofacial surgery, Moscow, Russian Federation
First Moscow state medical university named after I.M. Setchenov, Russian Federation

Author for correspondence.
PhD, professor, Head of the Department of Periodontology of Central Research Institute of Dental and Maxillofacial Surgery, Professor of the Department of Dentistry of I.M. Sechenov First Moscow State Medical University. Address: 119992, Moscow, Timur Frunze St., 16; tel.: (499) 246-82-58 Russian Federation

M. K. Makeeva

Central research institute of dental and maxillofacial surgery, Moscow, Russian Federation

postgraduate of the Department of Periodontology of Central Research Institute of Dental and Maxillofacial Surgery. Address: 119992, Moscow, Timur Frunze St., 16; tel.: (499) 246-13-34 Russian Federation

N. V. Pyatigorskaya

I.M. Setchenov First Moscow state medical university, Russian Federation

PhD, Deputy director for Research of Research Institute of Pharmacy, professor of the Department of Industrial Pharmacy, I.M. Sechenov First Moscow State Medical University. Address: 117418, Moscow, Nakhimovsky Ave, 45; tel.: (499) 128-57-55 Russian Federation


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