Kidney Injury in Newborns with Abdominal Compartment Syndrome

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Abstract

The review represents the problems of a damage to the vital organs in newborns with the Abdominal Compartment Syndrome (ACS). Particular attention is paid to the key predisposing factors and key links of the renal damage’s pathogenesis in newborns with ACS. This review presents the latest data about the role of the hypoxia at the initiation of damage of the renal parenchyma, the prospects for the use of various molecular markers for early diagnostics of nephropathy. Creation of molecular cell test system for the diagnostics and monitoring of renal damage in newborns with ACS is a promising trend in the treatment and prevention nephropathy in newborns.

About the authors

Dmitriy Anatol'evich Morozov

Scientific Centre of Children Health; Sechenov First Moscow State Medical University

Email: damorozov@list.ru
MD, PhD, Professor Russian Federation

Ol'ga Leonidovna Morozova

Sechenov First Moscow State Medical University

Author for correspondence.
Email: morozova_ol@list.ru
MD, PhD, Professor Russian Federation

Aleksey Aleksandrovich Tsyplakov

Saratov State Medical University n. a. V.I. Razumovsky

Email: ambu83@mail.ru
MD, PhD-student Russian Federation

Yuliya Aleksandrovna Mel'nikova

Sechenov First Moscow State Medical University

Email: yumka2007@yandex.ru
student Russian Federation

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