Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC94810.15690/vramn948HEALTH CARE MANAGEMENT: CURRENT ISSUESАКТУАЛЬНЫЕ ВОПРОСЫ ОРГАНИЗАЦИИ ЗДРАВООХРАНЕНИЯClinical Trials: What, Where, When?Клинические исследования: что, где, когда?https://orcid.org/0000-0003-0098-1403KobyakovaOlga S.КобяковаОльга Сергеевна
Russian Federation

Head of Division of General medical practice of Siberian State Medical University, DMedSc, professor.

2, Moscovsky trakt, 634050 Tomsk.

SPIN-код: 1373-0903

Доктор медицинских наук, профессор, заведующая кафедрой общей врачебной практики и поликлинической терапии.

634050, Томск, Московский тракт, д. 2.

SPIN-код: 1373-0903

olga_kobyakova@rambler.ruhttps://orcid.org/0000-0002-4449-4810DeevIvan A.ДеевИван Анатольевич
Russian Federation

Professor of Division of Faculty pediatrics, DMedSc.

SPIN-код: 2730-0004

Доктор медицинских наук, профессор кафедры факультетской педиатрии с курсом детских болезней лечебного факультета.

634050, Томск, Московский тракт, д. 2.

SPIN-код: 2730-0004

ivandeyev@yandex.ruhttps://orcid.org/0000-0002-0088-9204KulikovEvgeny S.КуликовЕвгений Сергеевич

Professor of Division of General medical practice of Siberian State Medical University, DMedSc.

SPIN-код: 9934-1476

Доктор медицинских наук, профессор кафедры общей врачебной практики и поликлинической терапии.

634050, Томск, Московский тракт, д. 2.

SPIN-код: 9934-1476

evgeny.s.kulikov@gmail.comhttps://orcid.org/0000-0001-9060-7428ShtykhRoman I.ШтыхРоман Игоревич
Russian Federation

Student.

SPIN-код: 3988-4881

Студент 3-го курса лечебного факультета.

634050, Томск, Московский тракт, д. 2.

SPIN-код: 3988-4881

shtykh.roman@gmail.comhttps://orcid.org/0000-0003-3866-100XPimenovIgor D.ПименовИгорь Дмитриевич
Russian Federation

Resident.

SPIN-код: 3757-0769

Ординатор кафедры общей врачебной практики и поликлинической терапии.

634050, Томск, Московский тракт, д. 2.

SPIN-код: 3757-0769

igor.d.pimenov@gmail.comhttps://orcid.org/0000-0001-5548-7491ZvonarevaOlga I.ЗвонареваОльга Игоревна
Russian Federation

Researcher at the Central Research Laboratory.

SPIN-код: 9145-4513

Научный сотрудник центральной научно-исследовательской лаборатории.

634050, Томск, Московский тракт, д. 2.

SPIN-код: 9145-4513

zvonoks@gmail.comhttps://orcid.org/0000-0003-0700-121XMareevIgor V.МареевИгорь Владимирович
Russian Federation

Clinical pharmacologist at Goldberg Research Institute of Pharmacology and Regenerative Medicine.

SPIN-код: 9629-3810

Клинический фармаколог, Научно-исследовательский институт фармакологии и регенеративной медицины имени Е.Д. Гольдберга.

SPIN-код: 9629-3810

igor.mareev@pharmso.ruSiberian State Medical UniversityСибирский государственный медицинский университетGoldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Сеntеr of the Russian Academy of SciencesТомский национальный исследовательский медицинский центр Российской академии наук201120187353143202203201822102018Copyright ©; 2018, "Paediatrician" Publishers LLCCopyright ©; 2018, Издательство "Педиатръ"2018"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/about/submissionshttps://vestnikramn.spr-journal.ru/jour/article/view/948

Currently randomized clinical trials (RCTs) are a key stage in the development of new drugs. Despite the huge scale of the CT market, general awareness of the issue remains low and the society has formed a number of stereotypes and misconceptions about CTs. The presented review of Russian and foreign studies provides the information on the level of general awareness of clinical research in different countries, as well as among patients and practitioners. The conducted literature analysis demonstrates that awareness of clinical trials remains low both in society at large and among patients or in the professional community of practitioners. According to foreign studies, only 20–30% of respondents have heard anything about medical research while a relatively small percentage of respondents have more complete knowledge of RCTs. Among practitioners, only one in five is sufficiently informed about CTs while, according to different data, only about half fully realize what evidence-based medicine is and understand the importance of CTs as a source of reliable knowledge in everyday practice.

На сегодняшний день рандомизированные клинические исследования являются ключевым этапом разработки новых лекарственных средств. Несмотря на огромный масштаб выполняемых исследований, осведомленность о данной области в целом остается низкой, а в обществе сформирован ряд стереотипов и заблуждений об их проведении. Данный обзор отечественных и зарубежных работ представляет уровень осведомленности о клинических исследованиях в разных странах в обществе в целом, а также среди пациентов и практикующих врачей в частности. По данным опроса зарубежных респондентов, только 20–30% из них слышали что-либо о медицинских исследованиях, при этом более полными знаниями обладает сравнительно небольшой процент опрошенных. Среди врачей только каждый пятый достаточно осведомлен о научных исследованиях, при этом, по разным данным, около половины опрошенных в полной мере понимают их важность как источника надежных знаний для клинической практики и имеют представление, что такое доказательная медицина.

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