Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC54310.15690/vramn.v70.i5.1438ONCOLOGY: CURRENT ISSUESАКТУАЛЬНЫЕ ВОПРОСЫ ОНКОЛОГИИVitamin D — A New Vector of Cancer Prevention?Витамин D — новый вектор профилактики онкологических заболеваний?KobyakovaO. S.КобяковаО. С.
Russian Federation

доктор медицинских наук, профессор, заведующая кафедрой общей врачебной практики с курсом поликлинической терапии СибГМУ, ректор СибГМУ Адрес: 634050, Томск, Московский тракт, д. 2, тел.: + 7 (3822) 53-04-23

olga_kobyakova@rambler.ruDeevI. A.ДеевИ. А.
Russian Federation

доктор медицинских наук, профессор кафедры факультетской педиатрии с курсом детских болезней лечебного факультета СибГМУ, проректор по развитию – первый проректор СибГМУ Адрес: 634050, Томск, Московский тракт, д. 2, тел.: + 7 (3822) 53-04-23

ivandeyev@yandex.ruTyufilinD. S.ТюфилинД. С.
Russian Federation

студент VI курса лечебного факультета СибГМУ Адрес: 634050, Томск, Московский тракт, д. 2, тел.: + 7 (3822) 52-77-47

dtufilin@gmail.comKulikovE. S.КуликовЕ. С.
Russian Federation

доктор медицинских наук, доцент кафедры общей врачебной практики с курсом поликлинической терапии СибГМУ, начальник научного управления СибГМУ Адрес: 634050, Томск, ул. Московский тракт, д. 2, тел.: + 7 (3822) 52-77-47

evgeny.s.kulikov@gmail.comSiberian State Medical University, Tomsk, Russian FederationСибирский государственный медицинский университет, Томск, Российская Федерация031220157055265330212201502122015Copyright ©; 2015, "Paediatrician" Publishers LLCCopyright ©; 2015, Издательство "Педиатръ"2015"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/article/view/543

Currently, a great number of research projects are focused on finding new treatment methods for cancer and carcinogenesis predictors, as well as the ways to dicrease cancer development risks. This article provides an overview of research on vitamin D as cancer prevention factor. The results of independent experiments and in vitro tests explaining the mechanisms of protective effect of vitamin D and its derivatives on cancer are illustrated. The review of epidemiological survey results obtained from different countries and various populations that were focused on the association of vitamin D use with various cancer pathologies incidence was performed.

В настоящее время большое число исследований посвящено поиску новых методов лечения онкологических болезней, а также предикторов канцерогенеза и способов коррекции риска развития рака. В статье представлен обзор публикаций, посвященных исследованию витамина D как средства профилактики онкологических болезней, описаны результаты отдельных экспериментов и исследований in vitro, объясняющие механизмы протективного эффекта витамина D и его производных в отношении рака. Обобщены результаты эпидемиологических исследований, выполненных в разных странах и в различных популяциях, посвященных ассоциации применения витамина D с частотой встречаемости различных видов онкологической патологии.

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