Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC39510.15690/vramn.v69i9-10.1138SHORT MESSAGESКРАТКИЕ СООБЩЕНИЯHORMONAL CHANGES IN RESPONSE TO EXTREME ENVIRONMENT FACTORSГОРМОНАЛЬНЫЕ ИЗМЕНЕНИЯ В ОТВЕТ НА ЭКСТРЕМАЛЬНЫЕ ФАКТОРЫ ВНЕШНЕЙ СРЕДЫKubasovR. V.КубасовР. В.
Russian Federation

кандидат биологических наук, старший преподаватель кафедры мобилизационной под- готовки здравоохранения и медицины катастроф СГМУ Адрес: 163061, Архангельск, Троицкий пр-т, д. 51, тел.: +7 (8182) 24-22-65

romanas2001@gmail.comNorthern State Medical University, ArkhangelskСеверный государственный медицинский университет, Архангельск, Российская Федерация20102014699-10Vestnik Rossiiskoi akademii medetsinskikh nauk / Annals of the Russian academy of medical sciencesВестник Российской академии медицинских наук10210907082015Copyright ©; 1970, "Paediatrician" Publishers LLCCopyright ©; 1970, Издательство "Педиатръ"1970"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/about/submissionshttps://vestnikramn.spr-journal.ru/jour/article/view/395

In this paper presented current state about hormonal changes in sympathetic-adrenal, hypophysis-adrenal, hypophysis-gonads and thyroid levels from extreme environment factors. It’s shown that hypophysis gonads and thyroid endocrine links along with sympathetic adrenal, hypophysis adrenal axes are very important relevance in response to extreme environment factors and organism adaptation. In this time a hormonal secretion changes corresponds as interrelated reactions cascade in mechanisms of homeostasis maintenance. A studying of this mechanisms and revealing of its role in stress pathogenesis is fundamental biomedical investigation task. A problem solving allow to perfect prophylactic and treatment methods against stress diseases.

На основании анализа данных литературы изложены современные представления об изменениях функционирования эндокринной регуляции, происходящих под влиянием различных факторов внешней среды. Показано, что гипоталамо-гипофизарно-гонадная и тиреоидная ось эндокринной регуляции, наряду с симпатоадреналовым и гипоталамо-гипофизарно-надпочечниковым звеньями, играют важнейшую роль в ответе на экстремальные воздействия внешней среды и адаптации организма. При этом в механизмах поддержания гомеостаза организма изменения гормональной секреции представляют собой своеобразный каскад тесно взаимосвязанных реакций. Изучение этих механизмов и выяснение их роли в патогенезе вызываемых нарушений — фундаментальная проблема биомедицинских исследований. Ее решение позволит совершенствовать способы профилактики и лечения заболеваний, обусловленных стрессом.

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