The article presents information about the international project «Healthy cities», knowledge about principles and axioms of the project. The authors have analyzed the experience of producing the «City Health Profile» under the project WHO «Healthy cities». The authors believe that the «Health Profile» of each individual city varies depending on specific conditions, both physical (the size of the territory, the state of the environment, its location) and political, and socio-economic. However, the formation of the «City Health Profile» is universally, regardless of geographical location or structure. It was noted that the «City Health Profile» has reflected all aspects of the life of the city, facilitates or barriers the promotion of inhabitants’ health and their well-being. For producing of «City Health Profile» additional data are needed: survey, sociological polls of the city population (self-assessment of their health status, lifestyle and quality of life). The advantage of these researches, carried out in the framework of the project «Healthy Cities», is implementation of complex sociological survey with a focused multi-purpose monitoring, covering all spheres of life in the city, to present a versatile, complete and objective evidences to illustrate the city as a territory of health and make up the holistic picture and the centre of which is the citizen and his/her health according to the WHO recommendations.