Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC206410.15690/vramn2064GASTROENTEROLOGY: CURRENT ISSUESАКТУАЛЬНЫЕ ВОПРОСЫ ГАСТРОЭНТЕРОЛОГИИReview ArticleDiagnostic Possibilities of Magnetic Resonance Cholangiography with Intravenous Contrast in Diseases of the Bile DuctsДиагностические возможности магнитно-резонансной панкреатохолангиографии с внутривенным контрастированием гадоксетовой кислотой при заболеваниях желчных протоковhttps://orcid.org/0000-0002-9357-09985964-2369KarmazanovskyGrigoriy G.КармазановскийГригорий Григорьевич
Russian Federation

MD, PhD, Professor, Corresponding Member of the RAS

д.м.н., профессор, член-корреспондент РАН

karmazanovsky@ixv.ruhttps://orcid.org/0000-0002-0204-83371101-6874ChzhaoAlexey V.ЧжаоАлексей Владимирович
Russian Federation

MD, PhD, Professor

д.м.н., профессор

chzhao@ixv.ruhttps://orcid.org/0000-0002-4115-69633954-7051AyvazyanKhachatur A.АйвазянХачатур Акопович
Russian Federation

Researcher Associate

научный сотрудник

ayvazyan@ixv.ruhttps://orcid.org/0000-0002-3528-036X1749-7490GoncharovAnton B.ГончаровАнтон Борисович
Russian Federation

Researcher Associate

научный сотрудник

goncharov@ixv.ruhttps://orcid.org/0000-0003-4273-171XSaraevaVeronika A.СараеваВероника Анатольевна
Russian Federation

PhD Student

аспирант

saraeva@ixv.ruhttps://orcid.org/0000-0003-1176-12037877-1999TrifonovSergey A.ТрифоновСергей Александрович
Russian Federation

MD

врач-хирург

trifonov@ixv.ruVishnevsky National Medical Research Center of SurgeryНациональный медицинский исследовательский центр хирургии имени А.В. Вишневского281220227753203250104202203112022Copyright ©; 2022, "Paediatrician" Publishers LLCCopyright ©; 2022, Издательство "Педиатръ"2022"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/about/submissionshttps://vestnikramn.spr-journal.ru/jour/article/view/2064

Every year the number of operations on the hepatobiliary zone is steadily increasing due to diseases of the bile ducts. Against this background, there is a need for an accurate diagnosis of complications of these interventions; classical magnetic resonance cholangiopancreatography (MRCP) is of limited use. With the introduction of a liver-specific contrast agent (Gd-EOB-DTPA), the possibility of diagnosing diseases of the bile ducts has expanded. In this clinical review, we review the technical aspects and benefits of Gd-EOB-DTPA-enhanced MR cholangiography. Various types of contrast agents, methods of their use in MRI, the dependence of the signal intensity in the bile ducts on the time of administration of the substance, the presence of chronic liver diseases are covered in detail. Separately, studies are given on the diagnosis of diseases of the bile ducts with altered biliary anatomy, biliary fistulas after surgical interventions. In conclusion, data are presented on promising studies of the functional state of the liver based on the use of MRI with hepatotropic contrast enhancement.

С каждым годом неуклонно возрастает число операций на гепатобилиарной зоне в связи заболеваниями желчных протоков. На фоне этого возникает потребность в точной диагностике осложнений данных вмешательств, классическая магнитно-резонансная панкреатохолангиография (МРХПГ) имеет ограниченное применение. С внедрением гепатропного контрастного вещества (гадоксетовой кислоты) расширилась возможность диагностики заболеваний желчных протоков. В данном клиническом обзоре мы рассматриваем технические аспекты и преимущество МРХПГ с гепатотропным контрастированием. Подробно освещаются различные виды контрастных веществ, способы их применение при МРТ, зависимость интенсивности сигнала в желчных протоках от времени введения вещества, наличие хронических заболеваний печени. Отдельно приводятся исследования по диагностике заболеваний желчных протоков при измененной билиарной анатомии, желчных свищях после хирургических вмешательств. В заключение приводятся данные о перспективных исследованиях функционального состояния печени на основе применения МРТ с гепатотропным контрастированием.

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