Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC19110.15690/vramn.v68i4.606PEDIATRICS: CURRENT ISSUESАКТУАЛЬНЫЕ ВОПРОСЫ ПЕДИАТРИИTHE PREVALENCE ОF FOOD ALLERGIES IN CHILDREN IN WORLD NIDUS OF OPISTHORCHIASIS: BACKGROUND AND STUDY METHODOLOGY OF EPIDEMIOLOGICAL SURVEY EUROPREVALLРАСПРОСТРАНЕННОСТЬ ПИЩЕВОЙ АЛЛЕРГИИ У ДЕТЕЙ В МИРОВОМ ОЧАГЕ ОПИСТОРХОЗА: ПЛАНИРОВАНИЕ И МЕТОДОЛОГИЯ ЭПИДЕМИОЛОГИЧЕСКОГО ИССЛЕДОВАНИЯ EUROPREVALLFedorovaO. S.ФедороваО. С.
Russian Federation

PhD, Professor, Department of Pediatric Faculty with a Course of Children Diseases of the Medical Faculty State Budget Educational Institution Highest Vocational Education «Siberian State Medical University» Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

osf77@list.ruOgorodovaL. M.ОгородоваЛ. М.
Russian Federation

PhD, Professor, RAMS cor. member, Head of the Department of Department of Pediatric Faculty with a Course of Children Diseases of the Medical Faculty State Budget Educational Institution Highest Vocational Education «Siberian State Medical University» Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

lm-ogorodova@mail.ruFedotovaM. M.ФедотоваМ. М.
Russian Federation

Ph.D student, Department of Pediatric Faculty with a Course of Children Diseases of the Medical Faculty State Budget Educational Institution Highest Vocational Education «Siberian State Medical University» Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

letter.81@mail.ruEvdokimovaT. A.ЕвдокимоваТ. А.
Russian Federation

PhD, Postdoctoral student, Department of Pediatric Faculty with Course of Children Diseases of the Medical Faculty State Budget Educational Institution Highest Vocational Education «Siberian State Medical University» Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

et2005@yandex.ruDeevI. A.ДеевИ. А.
Russian Federation

PhD, Professor, Department of Pediatric Faculty with a Course of Children Diseases of the Medical Faculty State Budget Educational Institution Highest Vocational Education «Siberian State Medical University» » Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

ivandeyev@yandex.ruDeevaE. V.ДееваЕ. В.
Russian Federation

PhD, Tutor, Department of Pediatric Faculty with a Course of Children Diseases of the Medical Faculty State Budget Educational Institution Highest Vocational Education «Siberian State Medical University» Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

evgeniavk@yandex.ruKamaltynovaE. M.КамалтыноваЕ. М.
Russian Federation

PhD, Associate Professor, Department of Pediatric Faculty with a Course of Children Diseases of the Medical Faculty State Budget Educational Institution Highest Vocational Education «Siberian State Medical University» » Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

eleant21@yandex.ruKolomeetsI. L.КоломеецИ. Л.
Russian Federation

Resident, Department of Pediatric Faculty with a Course of Children Diseases of the Medical Faculty State Budget Educational Institution Highest Vocational Education «Siberian State Medical University» Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

kolomeets@bk.ruKulikovE. S.КуликовЕ. С.
Russian Federation

PhD, Postdoctoral student, Department of Hospital Therapy State Budget Educational Institution Highest Vocational Education «Siberian State Medical University». Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

evgeny.s.kulikov@gmail.comSelivanovaP. A.СеливановаП. А.
Russian Federation

PhD, Tutor, Department of Hospital Therapy State Budget Educational Institution Highest Vocational Education «Siberian State Medical University». Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

p.selivanova@mail.ruSpitskoZh. A.СпицкоЖ. А.
Russian Federation

Head of the Department of Commercialization оf Scientific Research State Budget Educational Institution Highest Vocational Education «Siberian State Medical University». Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

spitsko@yandex.ruStarovoitovaE. A.СтаровойтоваЕ. А.
Russian Federation

PhD, Associate Professor, Department of General Practice and Outpatient Therapy «Siberian State Medical University» Address: 634050, Tomsk, Moscovsky Trakt St., 2; tel.: +7(3822)514967

elena-starovoytova@yandex.ruSiberian State Medical University, Tomsk, Russian FederationСибирский государственный медицинский университет, Томск, Российская Федерация14042013684Vestnik Rossiiskoi akademii medetsinskikh nauk / Annals of the Russian academy of medical sciencesВестник Российской академии медицинских наук182407082015Copyright ©; 1970, "Paediatrician" Publishers LLCCopyright ©; 1970, Издательство "Педиатръ"1970"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/about/submissionshttps://vestnikramn.spr-journal.ru/jour/article/view/191

According to numerous surveys food allergy affects up to 2–6% of population in different countries and varies due to numerous factors including the prevalence of helminths infestation. The food allergy prevalence data in Russia are based on official medical statistics. The study was performed as part of «The Prevalence, Cost and Basis of Food Allergy Across Europe» (EU funded project № FP6-2006-TTC-TU-5 Proposal 045879 EuroPrevall). The aim is to create the concept of food allergy in children in opisthorchiasis endemic area based on epidemiological study of the prevalence, risk factors and clinical features. The main objective of the study will be the working out of the food safety regulations. This article describes the study design and its methodology.

Согласно данным ряда исследователей, распространенность пищевой аллергии в мире составляет 2–6%, варьируя в зависимости от многочисленных факторов, включая пораженность населения гельминтными инвазиями. Сведения о распространенности пищевой аллергии в России основаны на данных официальной статистики. Настоящая работа выполнена в рамках «Исследования распространенности, социально-экономического значения и основ пищевой аллергии в Европе» («The Prevalence, Cost and Basis of Food Allergy Across Europe»; грант VI рамочной программы Евросоюза № FP6-2006-TTC-TU-5 Proposal 045879 EuroPrevall). Цель исследования состоит в формулировке новой концепции пищевой аллергии у детей в мировом очаге описторхоза на основании эпидемиологического исследования распространенности, факторов риска, клинических особенностей болезни, а также в создании научной базы для разработки регламентов безопасности продуктов питания. Статья посвящена вопросам планирования и методологии исследования.

food allergyOpisthorchis felineus invasionepidemiological studyskin-prick testsspecific IgЕcomponent-resolved diagnosticпищевая аллергияописторхозэпидемиологическое исследованиекожные прик-тестыспецифический IgЕкомпонентная аллергологическая диагностика1. Rona R.J., Keil T., Summers C., Gislason D., Zuidmeer L., Sodergren E., Sigurdardottir S.T., Lindner T., Goldhahn K., Dahlstrom J., McBride D., Madsen C. The prevalence of food allergy: а meta-analysis. J. Allergy Clin. Immunol. 2007; 120 (3): 638–646.2. Sampson H.A. Update on food allergy. J. Аllergy Сlin. Immunol. 2004: 113(5): 805–819.3. Boyce J.A., Assa'ad A., Burks A.W., Jones S.M., Sampson H.A., Wood R.A., Plaut M., Cooper S.F., Fenton M.J., Arshad S.H., Bahna S.L., Beck L.A., Byrd-Bredbenner C., Camargo C.A. Jr., Eichenfield L., Furuta G.T., Hanifin J.M., Jones C., Kraft M., Levy B.D., Lieberman P., Luccioli S., McCall K.M., Schneider L.C., Simon R.A., Simons F.E., Teach S.J., Yawn B.P., Schwaninger J.M. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J. Allergy Clin. Immunol. 2010; 126 (6): 1–58.4. Fedorova O.S., Ogorodova L.M., Solodovnikova O.V., Gonsorunova D.S. Pediatriya = Pediatrics. 2009; 2 (87): 116–125.5. Ben-Shoshan M., Clarke A.E. Food-induced anaphylaxis: Clinical highlights and knowledge gaps. Paediatr. Child. Health. 2012; 17 (1): 29–30.6. Mills E.N., Mackie A.R., Burney P., Beyer K., Frewer L., Madsen C., Botjes E., Crevel R.W., van Ree R. The prevalence, cost and basis of food allergy across Europe. Allergy. 2007; 62: 717–722.7. Potemkina A.M. Diagnostika i lechenie allergicheskikh zabolevanii u detei [Diagnosis and treatment of allergic diseases in children]. Kazan, Kazan University, 1990.8. Sergeev A.V., Mokronosova M.A. Allergologiya = Allergology. 2002; 1: 51–55.9. Varlamov E.E. Klinicheskoe znachenie, prognoz techeniya i effektivnost' lecheniya pishchevoi allergii u detei rannego vozrasta s atopicheskim dermatitom. Avtoref .diss. k.m.n. [Clinical significance and prognosis of the treatment effectiveness of food allergy in infants with atopic dermatitis. Abstract for Dissertation for the degree of Candidate of medical science] Moscow, 2009. 32 p.10. Cooper P.J. Interactions between helminth parasites and allergy. Curr. Opin. Allergy Clin. Immunol. 2009; 9 (1): 29–37.11. Strachan D.P. Hayfever, hygiene, and household size. BMJ. 1989; 299: 1259–1262.12. Bronshtein A.M. Malyshev N.A. RMZh = Russian Medical Journal. 2004; 12 (4): 21–23.13. Ogorodova L.M., Freidin M.B., Sazonov A.E, Fedorova O.S., Gerbek I.E., Cherevko N.A., Lebedeva N.Y. A pilot screening of prevalence of atopic states and opisthorchosis and their relationship in people of Tomsk Oblast. Parasitol. Res. 2007; 101: 1165–1168.14. Wong G.W., Mahesh P.A., Ogorodova L., Leung T.F., Fedorova O., Holla A.D., Fernandez-Rivas M., Clare Mills E.N., Kummeling I., van Ree R., Yazdanbakhsh M., Burney P. The EuroPrevall-INCO surveys on the prevalence of food allergies in children from China, India and Russia: the study methodology. Allergy. 2009; 65: 385–390.15. Position paper: Allergen standardization and skin tests. The European Academy of Allergology and Clinical Immunology. Allergy. 1993; 48 (Suppl. 14): 48–82.