Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC19010.15690/vramn.v68i4.605PEDIATRICS: CURRENT ISSUESАКТУАЛЬНЫЕ ВОПРОСЫ ПЕДИАТРИИEVALUATION OF PREMATURE INFANTS NUTRITIONAL STATUS BY AIR PLETHYSMOGRAPHY: FIRST RUSSIAN PROSPECTIVE STUDYОЦЕНКА НУТРИТИВНОГО СТАТУСА НЕДОНОШЕННЫХ ДЕТЕЙ МЕТОДОМ ВОЗДУШНОЙ ПЛЕТИЗМОГРАФИИ: ПЕРВОЕ РОССИЙСКОЕ ПРОСПЕКТИВНОЕ НАБЛЮДЕНИЕBaranovA. A.БарановА. А.
Russian Federation

PhD, Professor, RAS and RAMS academician, Director Federal State Budgetary Institution «Scientific Centre of Children,s Health» of RAMS Address: 119991, Moscow Lomonosov Prospect 2/1; tel.: (499) 134-30-83

baranov@nczd.ruNamazova-BaranovaL. S.Намазова–БарановаЛ. С.
Russian Federation

Phd, Professor, RAMS cor. member, Director of Research Institute of Preventive Pediatrics and Rehabilitation Treatment of Scientific Centre of Children,s Health, Head of the Department of Pediatric Faculty Pirogov Russian National Research Medical University Address: 119991, Moscow Lomonosov Prospect 2/2; tel.: (495) 967-14-14

namazova@nczd.ruBelyaevaI. A.БеляеваИ. А.
Russian Federation

PhD, Head of the Department of Department for Premature Babies, Research Institute of Pediatry, Federal State Budgetary Institution « Scientific Centre of Children,s Health» Address: 119991, Moscow Lomonosov Prospect 2/1; tel.: (499) 134-15-19

belyaeva@nczd.ruSkvortsovaV. A.СкворцоваВ. А.
Russian Federation

PhD, Professor, Leading Research Worker of Department of Nutrition a Healthy and Sick Child, Research Institute of Pediatry, Federal State Budgetary Institution « Scientific Centre of Children,s Health » Address: 119991, Moscow Lomonosov Prospect 2/1; tel.: (499) 132-26-00

vera.skvortsova@mail.ruTurtiT. V.ТуртиТ. В.
Russian Federation

PhD, Chief Medical Officer of Research Institute of Preventive Pediatrics and Rehabilitation Treatment, Federal State Budgetary Institution « Scientific Centre of Children,s Health » Address: 119991, Moscow Lomonosov Prospect 2/2; tel.: (499) 134-07-45

turti@nczd.ruTarzyanE. O.ТарзянЭ. О.
Russian Federation

Ph.D Student of Federal State Budgetary Institution « Scientific Centre of Children,s Health» Address: 119991, Moscow Lomonosov Prospect 2/1; tel.: (499) 134-15-19

eleonora027@mail.ruScientific Centre of Children’s Health RAMS, Moscow, Russian FederationНаучный центр здоровья детей РАМН, Москва, Российская Федерация14042013684Vestnik Rossiiskoi akademii medetsinskikh nauk / Annals of the Russian academy of medical sciencesВестник Российской академии медицинских наук101607082015Copyright ©; 1970, "Paediatrician" Publishers LLCCopyright ©; 1970, Издательство "Педиатръ"1970"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/about/submissionshttps://vestnikramn.spr-journal.ru/jour/article/view/190

In this article results of first Russian study on premature infants body composition in association with trend of their physical development within the first month and according to way of feeding. 30 preterm newborns without signs of intrauterine hypotrophy at birth with gestational age less than 35 month were examined by air body plethysmography. The infants were examined reaching term corrected age. Less levels of fat-free mass and increased percentage of fat were found in premature infants. The negative association between gestational age and the specific content of fat was found. This increases the risk of long-term metabolic diseases in preterm infants. It is found that preterm infants fed by fortified human milk have a more optimal body composition (less body fat levels) than infants fed by formula. The found consistent patterns confirm the necessity of supplying preterm infants with human milk for more adequate formation of plastic processes.

Представлены результаты первого отечественного исследования состава тела недоношенных детей во взаимосвязи с динамикой их физического развития на первом месяце жизни и в зависимости от характера вскармливания. С помощью воздушной бодиплетизмографии обследовано 30 недоношенных новорожденных с гестационным возрастом 35 и менее недель, не имевших при рождении признаков внутриутробной гипотрофии. Дети обследовались по достижении ими постконцептуального возраста 38–42 нед. У недоношенных детей установлены меньшие показатели безжировой массы тела и увеличенное процентное содержание жира. Обнаружена отрицательная корреляция между гестационным возрастом и удельным содержанием жировой ткани, что увеличивает риск отдаленных метаболических расстройств у маловесных недоношенных детей. Установлено, что недоношенные дети, вскармливаемые грудным молоком с обогатителем, имеют наиболее оптимальный состав тела (меньше жировой массы), чем дети, получающие специализированную смесь. Выявленные закономерности подтверждают необходимость обеспечения недоношенных детей грудным молоком для наиболее адекватного становления пластических процессов.

preterm infantsbody compositionair plethysmographyfeeding infantsmetabolic syndromeнедоношенные детисостав телавоздушная плетизмографиявскармливание младенцевметаболический синдром1. Barker D.J., Eriksson J.G., Forsen T., Osmond C. Fetal origins of adult disease: strength of effects and biological basis. Int. J. Epidemiol. 2002; 31: 1235–1239.2. Finken M.J., Keijzer-Veen M.G., Dekker F.W. Preterm birth and later insulin resistance: effects of birth weight and postnatal growth in a population based longitudinal study from birth into adult life insulin resistance 19 years after preterm birth. Diabetologia. 2006; 49: 478–485.3. Huxley R., Owen C.G., Whincup P.H. Is birth weight a risk factor for ischemic heart disease in later life? Am. J. Clin. Nutr. 2007; 85: 1244–1250.4. Stettler N., Stallings V.A., Troxel A.B. Weight gain in the first week of life and overweight in adulthood: a cohort study of European American subjects fed infant formula. Circulation. 2005; 111: 1897–1903.5. Agostoni C., Buonocore G., Carnielli V.P., De Curtis M, Darmaun D, Decsi T, Domellöf M, Embleton ND, Fusch C, Genzel-Boroviczeny O, Goulet O, Kalhan SC, Kolacek S, Koletzko B, Lapillonne A, Mihatsch W, Moreno L, Neu J, Poindexter B, Puntis J, Putet G, Rigo J, Riskin A, Salle B, Sauer P, Shamir R, Szajewska H, Thureen P, Turck D, van Goudoever JB, Ziegler EE. Enteral nutrient supply for preterm infants: commentary from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition Committee on Nutrition. J. Pediatr. Gastroenterol. Nutr. 2010; 50: 85–91.6. Lemons J.A., Bauer C.R., Oh W. Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 through December 1996. NICHD Neonatal Research Network. Pediatrics. 2001; 107: 1.7. Fenton T.R. A new growth chart for preterm babies: Babson and Benda’s chart updated with recent data and a new format. BMC Pediatr. 2003; 3: 13.8. Ma G.S., Yao M., Liu Y. Validation of a new pediatric air displacement plethysmograph for assessing body composition in infants. Am. J. Clin. Nutr. 2004; 79: 653–660.9. Rogerro P., Giannı` M.L., Amato O., Orsi A., Piemontese P., Morlacchi L., Mosca F. Is term newborn body composition being achieved postnatally in preterm infants? Early Hum. Dev. 2009; 85: 349–352.10. Cooke R.J., Griffin I. Altered body composition in preterm infants at hospital discharge. Acta Paediatr. 2009; 98: 1269–1273.11. Ramel S., Gray H., Ode K., Younge N., Georgieff M., Demerath E. Body сomposition сhanges in preterm infants following hospital discharge: comparison with term infants. JPGN. 2011; 53: 333–338.12. Grosheva E.V., Baibarina E.N., Degtyarev D.N., Lenyushkina A.A., Antonov A.G., Ryumina I.I., Yakovleva M.A. Optimization of enteral nutrition deeply preterm infants in the hospital. Akusherstvo i ginekologiya = Obstetrics and Gynecology. 2012; 2: 57–61.13. Roggero P., Gianni M.L., Amato O., Orsi A., Piemontese P., Puricelli V., Mosca F. Influence of protein and energy intakes on body composition of formula-fed preterm infants after term. J. Pediatr. Gastr. Nutr. 2008; 47: 375–378.14. Cooke R.J., McCormick K., Griffin I.J. Feeding preterm infants after hospital discharge: effect of diet on body composition. Pediatr. Res. 1999; 46: 461–464.15. Dewey K.G. Is breastfeeding protective against child obesity? J. Hum. Lact. 2003; 19: 9–18.