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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of the Russian academy of medical sciences</journal-id><journal-title-group><journal-title xml:lang="en">Annals of the Russian academy of medical sciences</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российской академии медицинских наук</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-6047</issn><issn publication-format="electronic">2414-3545</issn><publisher><publisher-name xml:lang="en">"Paediatrician" Publishers LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">18176</article-id><article-id pub-id-type="doi">10.15690/vramn18176</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>INFECTIOUS DISEASES: CURRENT ISSUES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>АКТУАЛЬНЫЕ ВОПРОСЫ ИНФЕКЦИОННЫХ БОЛЕЗНЕЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Study of antibacterial activity of zinc oxide coated textiles</article-title><trans-title-group xml:lang="ru"><trans-title>Изучение антибактериальной активности текстиля с покрытием на основе оксида цинка</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6268-5282</contrib-id><contrib-id contrib-id-type="spin">4561-7353</contrib-id><name-alternatives><name xml:lang="en"><surname>Korobova</surname><given-names>Anna G.</given-names></name><name xml:lang="ru"><surname>Коробова</surname><given-names>Анна Геннадьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>amalofeeva@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-7076-3206</contrib-id><contrib-id contrib-id-type="spin">8002-3786</contrib-id><name-alternatives><name xml:lang="en"><surname>Meshchurova</surname><given-names>Svetlana Y.</given-names></name><name xml:lang="ru"><surname>Мещурова</surname><given-names>Светлана Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>svetlana.meschurova@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6734-3989</contrib-id><contrib-id contrib-id-type="spin">5404-6202</contrib-id><name-alternatives><name xml:lang="en"><surname>Samokhodskaya</surname><given-names>Larisa M.</given-names></name><name xml:lang="ru"><surname>Самоходская</surname><given-names>Лариса Михайловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Assistant Professor</p></bio><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><email>slm@fbm.msu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-3940-6638</contrib-id><contrib-id contrib-id-type="spin">7933-1107</contrib-id><name-alternatives><name xml:lang="en"><surname>Kamler</surname><given-names>Anna V.</given-names></name><name xml:lang="ru"><surname>Камлер</surname><given-names>Анна Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD of Technical Sciences</p></bio><bio xml:lang="ru"><p>к.т.н.</p></bio><email>abramova@physics.msu.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-9916-6855</contrib-id><contrib-id contrib-id-type="spin">7095-8104</contrib-id><name-alternatives><name xml:lang="en"><surname>Ildyakov</surname><given-names>Aleksandr V.</given-names></name><name xml:lang="ru"><surname>Ильдяков</surname><given-names>Александр Валериевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>ildyakov.av@gmail.com</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-6705-5083</contrib-id><name-alternatives><name xml:lang="en"><surname>Chernyaev</surname><given-names>Andrey Y.</given-names></name><name xml:lang="ru"><surname>Черняев</surname><given-names>Андрей Яковлевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>cheernaev@imfd.ru</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4251-7545</contrib-id><contrib-id contrib-id-type="spin">6609-5468</contrib-id><name-alternatives><name xml:lang="en"><surname>Kamalov</surname><given-names>Armais A.</given-names></name><name xml:lang="ru"><surname>Камалов</surname><given-names>Армаис Альбертович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor, Academician of the RAS</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН</p></bio><email>armais.kamalov@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Medical Research and Education Institute Lomonosov Moscow State University</institution></aff><aff><institution xml:lang="ru">Медицинский научно-образовательный институт МГУ имени М.В. Ломоносова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Kurnakov Institute of General and Inorganic Chemistry, Russian of Academy of Sciences</institution></aff><aff><institution xml:lang="ru">Институт общей и неорганической химии имени Н.С. Курнакова Российской академии наук</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Institute for African Studies, Russian Academy of Sciences</institution></aff><aff><institution xml:lang="ru">Институт Африки Российской академии наук</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">INFOMEDFARM DIALOG LLC</institution></aff><aff><institution xml:lang="ru">Информационно-выставочное агентство «ИнфоМедФарм Диалог»</institution></aff></aff-alternatives><content-language>ru</content-language><pub-date date-type="pub" publication-format="electronic" iso-8601-date="2026-09-22"><day>22</day><month>09</month><year>2026</year></pub-date><pub-date date-type="collection"><year>2026</year></pub-date><volume>81</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>199</fpage><lpage>204</lpage><history><date date-type="received" iso-8601-date="2026-01-26"><day>26</day><month>01</month><year>2026</year></date><date date-type="accepted" iso-8601-date="2026-07-11"><day>11</day><month>07</month><year>2026</year></date></history><pub-history><event event-type="received"><event-desc>Received:<date date-type="received" iso-8601-date="2026-01-26"><day>26</day><month>01</month><year>2026</year></date></event-desc></event><event event-type="accepted"><event-desc>Accepted:<date date-type="accepted" iso-8601-date="2026-07-11"><day>11</day><month>07</month><year>2026</year></date></event-desc></event><event event-type="pub"><event-desc>Published:<pub-date date-type="pub" publication-format="electronic" iso-8601-date="2026-09-22"><day>22</day><month>09</month><year>2026</year></pub-date></event-desc></event></pub-history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, "Paediatrician" Publishers LLC</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, Издательство "Педиатръ"</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">"Paediatrician" Publishers LLC</copyright-holder><copyright-holder xml:lang="ru">Издательство "Педиатръ"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2027-03-22"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnikramn.spr-journal.ru/jour/about/submissions</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikramn.spr-journal.ru/jour/article/view/18176">https://vestnikramn.spr-journal.ru/jour/article/view/18176</self-uri><abstract xml:lang="en"><p><bold>Background. </bold>Nowadays, due to the widespread of antibiotic-resistant bacteria, in addition to traditional methods of treating surface infections using mechanical cleaning, antiseptics and antibiotics, variants of dressings with antibacterial coating with inorganic and hybrid nanoparticles are being investigated and tested. The development of affordable dressings and long-lasting medical textiles can significantly enhance the effectiveness of treatment and reduce the burden on healthcare systems.</p> <p><bold>Aims</bold> — evaluation of the antibacterial activity of textile samples treated with zinc oxide against the control strain Staphylococcus aureus ATCC 25923 and the polyresistant clinical strains Klebsiella pneumoniae and Pseudomonas aeruginosa.</p> <p><bold>Methods.</bold> Studies were performed at the Microbiology Laboratory of the Medical Research and Education Institute Lomonosov Moscow State University. The antibacterial properties of textile samples treated with zinc oxide produced by Infomedpharm Dialog Information and Exhibition Agency were tested according to GOST R ISO 20743:2012. To evaluate the antibacterial activity, a reference strain of St. aureus ATCC 25923 was used, along with clinical strains of K. pneumoniae that produce metallo-carbapenemase NDM and serine carbapenemase OXA-48, and P. aeruginosa that produce VIM carbapenemase.</p> <p><bold>Results.</bold> The antibacterial activity of textile with antimicrobial coating based on zinc oxide against St. aureus ATCC 25923 was 7.29, against P. aeruginosa — 7.62, against K. pneumoniae — 9.15. The inhibitory ability of the studied textile with an antibacterial coating was 99% for all studied isolates.</p> <p><bold>Conclusions. </bold>We have confirmed the high antibacterial activity of antibacterial-coated textile after incubation with both Gram-positive microorganisms and Gram-negative polyresistant isolates.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование. </bold>В настоящее время в связи с широким распространением бактерий, устойчивых к антибиотикам, помимо традиционных методов лечения поверхностных инфекций с помощью механической очистки, антисептиков и антибиотиков исследуются и тестируются варианты перевязочных материалов с антибактериальным покрытием неорганическими и гибридными наночастицами. Внедрение доступных перевязочных материалов и медицинского текстиля длительного действия может существенно повысить качество лечения и снизить нагрузку на системы здравоохранения.</p> <p><bold>Цель исследования</bold> — оценка антибактериальной активности образцов текстиля с покрытием на основе оксида цинка в отношении контрольного штамма Staphylococcus aureus ATCC 25923 и полирезистентных клинических штаммов Klebsiella pneumoniae и Pseudomonas aeruginosa.</p> <p><bold>Методы.</bold> Исследование проведено на базе лаборатории микробиологии Университетской клиники МНОИ МГУ имени М.В. Ломоносова. Антибактериальную активность образцов марли с покрытием на основе оксида цинка производства ООО «Информационно-выставочное агентство «ИнфоМедФарм Диалог» определяли в соответствии с ГОСТ Р ИСО 20743:2012. Для оценки антибактериальной активности использованы контрольный штамм St. aureus ATCC 25923, а также клинические штаммы K. pneumoniae с ко-продукцией металло-карбапенемаз NDM и сериновых карбапенемаз OXA-48 и P. aeruginosa с продукцией VIM карбапенемаз.</p> <p><bold>Результаты.</bold> Значение антибактериальной активности марли с антимикробным покрытием на основе оксида цинка против St. aureus ATCC 25923 составило 7,29; против P. aeruginosa — 7,62; против K. pneumoniae — 9,15. Ингибирующая способность исследуемой ткани с антибактериальным покрытием составила 99% в отношении всех исследуемых изолятов.</p> <p><bold>Заключение. </bold>Подтверждена высокая антибактериальная активность марли с антибактериальным покрытием на основе цинка при инкубации с контрольным штаммом St. aureus ATCC 25923 и полирезистентными клиническими штаммами K. pneumoniae и P. aeruginosa.</p></trans-abstract><kwd-group xml:lang="en"><kwd>antibacterial agents</kwd><kwd>biomedical materials</kwd><kwd>zinc oxide</kwd><kwd>nanoparticles</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>биомедицинские изделия</kwd><kwd>антибактериальные агенты</kwd><kwd>оксид цинка</kwd><kwd>наночастицы</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Goncharova DA, Bolbasov EN, Nemoykina AL, et al. Structure and Properties of Biodegradable PLLA/ZnO Composite Membrane Produced via Electrospinning. 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