Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC18110.15690/vramn.v68i5.658CELL TRANSPLANTOLOGY AND TISSUE ENGINEERING: CURRENT ISSUESАКТУАЛЬНЫЕ ВОПРОСЫ КЛЕТОЧНОЙ ТРАНСПЛАНТОЛОГИИ И ТКАНЕВОЙ ИНЖЕНЕРИИMETHODS OF TISSUE ENGINEERING OF BONE TISSUE IN MAXILLOFACIAL SURGERYМЕТОДЫ ТКАНЕВОЙ ИНЖЕНЕРИИ КОСТНОЙ ТКАНИ В ЧЕЛЮСТНО-ЛИЦЕВОЙ ХИРУРГИИLyundupA. V.ЛюндупА. В.
Russian Federation

PhD, Head of Department of Biomedical Research, Research Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University Address: 119992, Moscow, Trubetskaya St., 8/2; tel.: (495) 609-14-00

lyundup@gmail.comMedvedevYu. A.МедведевЮ. А.
Russian Federation

PhD, Professor, Head of Oral & Maxillofacial Surgery Department, Head of Maxillo-Facial Surgery Hospital, University Hospital No.2, I.M. Sechenov First Moscow State Medical University Address: 119992, Moscow, Pogodinskaya St., 1; tel.: (499) 248-27-50

uamedvedev@gmail.comBalasanovaK. V.БаласановаК. В.
Russian Federation

Clinical Resident, Department of Oral & Maxillofacial Surgery, Laboratory Assistant of Research and Education Clinical Center of New Technologies, I.M. Sechenov First Moscow State Medical University Address: 119992, Moscow, Pogodinskaya St., 1; tel.: (499) 248-27-50

midian_89@mail.ruZolopupN. M.ЗолотопупН. М.
Russian Federation

Intern, Department of Oral & Maxillofacial Surgery, I.M. Sechenov First Moscow State Medical University Address: 119992, Moscow, Pogodinskaya St., 1; tel.: (499) 248-27-50

golden_n@inbox.ruBrodskayaS. B.БродскаяС. Б.
Russian Federation

Research Worker, Research and Education Clinical Center of New Technologies in MaxilloFacial Surgery Hospital, I.M. Sechenov First Moscow State Medical University Address: 119992, Moscow, Pogodinskaya St., 1; tel.: (499) 248-27-50

sonyushka1@ya.ruElistratovP. A.ЕлистратовП. А.
Russian Federation

PhD, Research Worker of Department of Biomedical Research, Research Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University Address: 119992, Moscow, Trubetskaya St., 8/2; tel.: (495) 609-14-00

Flora85@yandex.ruSechenov First Moscow State Medical University, Russian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова, Российская Федерация14052013685Vestnik Rossiiskoi akademii medetsinskikh nauk / Annals of the Russian academy of medical sciencesВестник Российской академии медицинских наук101507082015Copyright ©; 1970, "Paediatrician" Publishers LLCCopyright ©; 1970, Издательство "Педиатръ"1970"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/article/view/181

For the last decade many experimental and clinical data about the study and application of regenerative medicine methods in the maxillofacial surgery were accumulated. For better bone regeneration mesenchymal stem cells are often used. Considering the general wariness of researchers in some aspects of cell therapy, methods of study of mesenchymal stem cells and the technologies of its clinical application are constantly being upgraded. This review will consider methods of tissue engineering used to regenerate bone tissue defects in maxillofacial surgery.

В последнее время накоплено достаточно экспериментальных и клинических данных по исследованию и применению методов регенеративной медицины в челюстно-лицевой хирургии. Для лучшего восстановления костной ткани часто используют мезенхимальные стволовые клетки. Учитывая общую настороженность исследователей в некоторых аспектах клеточной терапии, методы изучения и технологии использования мезенхимальных стволовых клеток постоянно совершенствуются. В обзоре описаны методы тканевой инженерии, применяемые для регенерации костной ткани при дефектах в челюстно-лицевой области.

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