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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of the Russian academy of medical sciences</journal-id><journal-title-group><journal-title xml:lang="en">Annals of the Russian academy of medical sciences</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российской академии медицинских наук</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-6047</issn><issn publication-format="electronic">2414-3545</issn><publisher><publisher-name xml:lang="en">"Paediatrician" Publishers LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">17976</article-id><article-id pub-id-type="doi">10.15690/vramn17976</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CARDIOLOGY AND CARDIOVASCULAR SURGERY: CURRENT ISSUES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>АКТУАЛЬНЫЕ ВОПРОСЫ КАРДИОЛОГИИ И СЕРДЕЧНО-СОСУДИСТОЙ ХИРУРГИИ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The Role of Modern Endovascular Innovative Technologies in Changing the Treatment Strategy for Coronary Heart Disease (Literature Review)</article-title><trans-title-group xml:lang="ru"><trans-title>Роль современных рентгенэндоваскулярных инновационных технологий в изменении стратегии лечения ишемической болезни сердца (обзор литературы)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6509-566X</contrib-id><contrib-id contrib-id-type="spin">1544-2818</contrib-id><name-alternatives><name xml:lang="en"><surname>Alekyan</surname><given-names>Bagrat G.</given-names></name><name xml:lang="ru"><surname>Алекян</surname><given-names>Баграт Гегамович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor, Academician of the RAS</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор, академик РАН</p></bio><email>bagrat.alekyan@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4204-1092</contrib-id><contrib-id contrib-id-type="spin">2271-1880</contrib-id><name-alternatives><name xml:lang="en"><surname>Meleshenko</surname><given-names>Nikolay N.</given-names></name><name xml:lang="ru"><surname>Мелешенко</surname><given-names>Николай Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук</p></bio><email>dr.meleshenko_nn@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-2809-9484</contrib-id><name-alternatives><name xml:lang="en"><surname>Atroshenko</surname><given-names>Vyacheslav V.</given-names></name><name xml:lang="ru"><surname>Атрошенко</surname><given-names>Вячеслав Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><bio xml:lang="ru"><p>врач</p></bio><email>atroshenko96@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Medical Research Center for Surgery named after A.V. Vishnevsky</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр хирургии имени А.В. Вишневского</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian Medical Academy of Continuing Professional Education</institution></aff><aff><institution xml:lang="ru">Российская медицинская академия непрерывного профессионального образования</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-07-07" publication-format="electronic"><day>07</day><month>07</month><year>2025</year></pub-date><volume>80</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>121</fpage><lpage>130</lpage><history><date date-type="received" iso-8601-date="2024-04-15"><day>15</day><month>04</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2025-04-21"><day>21</day><month>04</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, "Paediatrician" Publishers LLC</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Издательство "Педиатръ"</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">"Paediatrician" Publishers LLC</copyright-holder><copyright-holder xml:lang="ru">Издательство "Педиатръ"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2026-01-07"/></permissions><self-uri xlink:href="https://vestnikramn.spr-journal.ru/jour/article/view/17976">https://vestnikramn.spr-journal.ru/jour/article/view/17976</self-uri><abstract xml:lang="en"><p>Every year the number of endovascular diagnostic and therapeutic procedures performed in patients with coronary artery disease increases. Today, endovascular myocardial revascularization is the main method of treatment for coronary artery disease. The widespread use of this method became possible thanks to the development and introduction into clinical practice of modern drug-eluting stents, and the use of intravascular imaging and functional assessment of the coronary bed led to the optimization of PCI results and a change in the treatment strategy for patients with coronary artery disease. This review article presents both historical aspects of the development and implementation of these technologies, as well as modern studies and meta-analyses depicting the results of the use of these technologies in patients with multivessel or “severe” (diffuse, tandem, extended, calcified) lesions of the coronary arteries.</p></abstract><trans-abstract xml:lang="ru"><p>С каждым годом возрастает количество выполняемых эндоваскулярных диагностических и лечебных процедур у пациентов с ишемической болезнью сердца<bold> </bold>(ИБС). На сегодняшний день эндоваскулярная реваскуляризация миокарда является основным методом лечения ИБС. Широкое применение данного метода стало возможным благодаря развитию и внедрению в клиническую практику современных стентов с лекарственным покрытием, а применение внутрисосудистой визуализации и функциональной оценки коронарного русла привело к оптимизации результатов чрескожного коронарного вмешательства (ЧКВ) и смене стратегии лечения пациентов ИБС. В данной обзорной статье представлены как исторические аспекты развития и внедрения этих технологий, так и современные исследования и метаанализы, отображающие результаты применения данных технологий у пациентов с многососудистым или «тяжелым» (диффузные, тандемные, протяженные, кальцинированные) поражением коронарных артерий.</p></trans-abstract><kwd-group xml:lang="en"><kwd>stents</kwd><kwd>optical coherence tomography (OCT)</kwd><kwd>intravascular ultrasound (IVUS)</kwd><kwd>instantaneous wave-free ratio (iFR)</kwd><kwd>fractional flow reserve (FFR)</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>стенты</kwd><kwd>оптическая когерентная томография (ОКТ)</kwd><kwd>внутрисосудистое ультразвуковое исследование (ВСУЗИ)</kwd><kwd>моментальный резерв кровотока (мРК)</kwd><kwd>фракционный резерв кровотока (ФРК)</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Алшибая М.Д., Бокерия Л.А., Глянцев С.П. 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