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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of the Russian academy of medical sciences</journal-id><journal-title-group><journal-title xml:lang="en">Annals of the Russian academy of medical sciences</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российской академии медицинских наук</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-6047</issn><issn publication-format="electronic">2414-3545</issn><publisher><publisher-name xml:lang="en">"Paediatrician" Publishers LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">15995</article-id><article-id pub-id-type="doi">10.15690/vramn15995</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>INFECTIOUS DISEASES: CURRENT ISSUES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>АКТУАЛЬНЫЕ ВОПРОСЫ ИНФЕКЦИОННЫХ БОЛЕЗНЕЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Post COVID Syndrome: the Classification of Clinical Forms</article-title><trans-title-group xml:lang="ru"><trans-title>Постковидный синдром: классификация клинических форм</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3612-1889</contrib-id><contrib-id contrib-id-type="spin">1364-1257</contrib-id><name-alternatives><name xml:lang="en"><surname>Ploskireva</surname><given-names>Antonina A.</given-names></name><name xml:lang="ru"><surname>Плоскирева</surname><given-names>Антонина А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor of the RAS</p></bio><bio xml:lang="ru"><p>д.м.н., профессор РАН</p></bio><email>antonina@ploskireva.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9257-0171</contrib-id><contrib-id contrib-id-type="spin">3680-3186</contrib-id><name-alternatives><name xml:lang="en"><surname>Gorelov</surname><given-names>Alexander V.</given-names></name><name xml:lang="ru"><surname>Горелов</surname><given-names>Александр В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor, Academician of the RAS]</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН </p></bio><email>agorelov_05@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4185-9829</contrib-id><contrib-id contrib-id-type="spin">7906-4825</contrib-id><name-alternatives><name xml:lang="en"><surname>Letyushev</surname><given-names>Alexander N.</given-names></name><name xml:lang="ru"><surname>Летюшев</surname><given-names>Александр Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>letiushev_an@rospotrebnadzor.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9682-2230</contrib-id><contrib-id contrib-id-type="spin">1819-3911</contrib-id><name-alternatives><name xml:lang="en"><surname>Omarova</surname><given-names>Khadizhat G.</given-names></name><name xml:lang="ru"><surname>Омарова</surname><given-names>Хадижат Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>omarova71@inbox.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2269-2533</contrib-id><contrib-id contrib-id-type="spin">3568-1057</contrib-id><name-alternatives><name xml:lang="en"><surname>Muzyka</surname><given-names>Anna D.</given-names></name><name xml:lang="ru"><surname>Музыка</surname><given-names>Анна Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>к.м.н. </p></bio><email>nikolitch-anna@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Central Research Institute of Epidemiology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing</institution></aff><aff><institution xml:lang="ru">Центральный научно-исследовательский институт эпидемиологии Роспотребнадзора</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University (Pirogov Medical University)</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Federal Service for Supervision of Consumer Rights Protection and Human Well-Being</institution></aff><aff><institution xml:lang="ru">Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-12-28" publication-format="electronic"><day>28</day><month>12</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-12-13" publication-format="electronic"><day>13</day><month>12</month><year>2024</year></pub-date><volume>79</volume><issue>5</issue><issue-title xml:lang="ru"/><history><date date-type="received" iso-8601-date="2023-08-01"><day>01</day><month>08</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2024-10-13"><day>13</day><month>10</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, "Paediatrician" Publishers LLC</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Издательство "Педиатръ"</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">"Paediatrician" Publishers LLC</copyright-holder><copyright-holder xml:lang="ru">Издательство "Педиатръ"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-07-14"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnikramn.spr-journal.ru/jour/about/submissions</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikramn.spr-journal.ru/jour/article/view/15995">https://vestnikramn.spr-journal.ru/jour/article/view/15995</self-uri><abstract xml:lang="en"><p><bold>Background. </bold>After a coronavirus infection, a number of people have long-term health abnormalities, often requiring therapeutic intervention.</p> <p><bold>Aims</bold> — to describe the features of the course of the convalescence period in patients who have had a coronavirus infection caused by the SARS-CoV-2 virus.</p> <p><bold>Methods.</bold> A special questionnaire was prepared for patients, which included questions to assess the course of the convalescence period in patients who had a coronavirus infection caused by the SARS-CoV-2 virus. The survey was conducted electronically on the platform testograf.ru.</p> <p><bold>Results.</bold> The study involved 24,126 people aged 18 to 95 years. After the primary disease, 67.58% of respondents had complaints, and 66.1% had complaints after the second one. Asthenic syndrome, cognitive and memory disorders were most often recorded, as well as respiratory function disorders (cough, shortness of breath) and gastrointestinal tract functions (diarrhea, constipation, dyspepsia), olfactory and taste disorders, hair loss. Skin manifestations, decreased visual acuity, complaints of frequent acute respiratory infections, sleep disorders, prolonged subfebrility and others were rare. Among the group of patients who had an exacerbation of somatic pathology, the most significant were diseases of the cardiovascular system and musculoskeletal system. After a coronavirus infection in the form of pneumonia in the period of convalescence, respiratory disorders were significantly more often recorded, and in the gastrointestinal form, damage to the gastrointestinal tract.</p> <p><bold>Conclusions. </bold>the classification of clinical forms of postcovid syndrome includes four main blocks of clinical manifestations of the period of convalescence of coronavirus infection: virus-associated manifestations, iatrogenic, genetically determined, associated with somatic pathology.</p> <p> </p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование. </bold>После перенесенной коронавирусной инфекции у ряда лиц отмечаются длительные отклонения в состоянии здоровья, нередко требующие терапевтического вмешательства.</p> <p><bold>Цель исследования</bold> — описать особенности течения периода реконвалесценции у пациентов, которые перенесли коронавирусную инфекцию, вызванную вирусом SARS-CoV-2.</p> <p><bold>Методы.</bold> Был подготовлен специальный опросник для пациентов, который включал вопросы, позволяющие оценить течение периода реконвалесценции у пациентов, перенесших коронавирусную инфекцию, вызванную вирусом SARS-CoV-2. Опрос проводился в электронном виде на платформе testograf.ru.</p> <p><bold>Результаты.</bold> В исследовании приняли участие 24 126 человек в возрасте от 18 до 95 лет. После перенесенного первичного заболевания наличие жалоб отмечалось у 67,58% опрошенных, после повторного — у 66,1%. Наиболее часто регистрировались астенический синдром, когнитивные нарушения и нарушения памяти, а также имели место нарушения дыхательной функции (кашель, одышка) и функции желудочно-кишечного тракта (диарея, запор, диспепсия), нарушения обоняния и вкуса, выпадение волос. Редкими были кожные проявления, снижение остроты зрения, жалобы на частые острые респираторные инфекции, нарушение сна, длительный субфебрилитет и др. Среди группы пациентов, у которых отмечалось обострение соматической патологии, наиболее значимыми были заболевания сердечно-сосудистой системы и опорно-двигательного аппарата. После перенесенной коронавирусной инфекции в форме пневмонии в периоде реконвалесценции достоверно чаще регистрировались респираторные нарушения, а при гастроинтестинальной форме — поражение желудочно-кишечного тракта.</p> <p><bold>Заключение.</bold> По результатам исследования составлена классификация клинических форм постковидного синдрома, в которую включены четыре основных блока клинических проявлений периода реконвалесценции коронавирусной инфекции: вирус-ассоциированные проявления, ятрогенные, генетически обусловленные, связанные с соматической патологией.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Post COVID</kwd><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>постковидный синдром</kwd><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd></kwd-group><funding-group><award-group><funding-source><institution-wrap><institution xml:lang="ru">ФБУН ЦНИИ эпидемиологии Роспотребнадзора</institution></institution-wrap><institution-wrap><institution xml:lang="en">Federal Budgetary Scientific Institution Central Research Institute of Epidemiology of Rospotrebnadzor</institution></institution-wrap></funding-source></award-group></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>A clinical case definition of post COVID-19 condition by a Delphi consensus. 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