Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC1439210.15690/vramn14392PEDIATRICS: CURRENT ISSUESАКТУАЛЬНЫЕ ВОПРОСЫ ПЕДИАТРИИResearch ArticleA Single-Stage Population-Based Study of the Relationship between Cognitive and Somatic Health Parameters in Children of Secondary School AgeОдномоментное популяционное исследование связи параметров когнитивного и соматического здоровья у детей среднего школьного возрастаhttps://orcid.org/0000-0002-8540-38586248-0970KarkashadzeGeorge A.КаркашадзеГеоргий Арчилович
Russian Federation

MD, PhD

к.м.н.

karkga@mail.ruhttps://orcid.org/0000-0002-8936-35901272-7036KaitukovaElena V.КайтуковаЕлена Владимировна
Russian Federation

MD, PhD

к.м.н.

sunrise_ok@mail.ruhttps://orcid.org/0000-0001-9790-74905723-4805GogberashviliTinatin Y.ГогберашвилиТинатин Юзовна
Russian Federation

PhD of Psychological Sciences

к.психол.н.

tinatina2004@mail.ru7971-2040KonstantinidiTatiana A.КонстантинидиТатьяна Анатольевна
Russian Federation

MD, PhD

к.м.н.

tkonstantinidi@list.ruhttps://orcid.org/0000-0001-8311-95062562-7725GordeevaOlga B.ГордееваОльга Борисовна
Russian Federation

MD, PhD

к.м.н.

obr@yandex.ruhttps://orcid.org/0009-0000-0293-17715540-7933GazalievaAishat M.ГазалиеваАйшат Микаиловна
Russian Federation

MD, PhD

к.м.н.

a.m.gazalieva@gmail.comhttps://orcid.org/0000-0002-6150-08802954-9873SoloshenkoMargarita A.СолошенкоМаргарита Александровна
Russian Federation

MD, PhD

к.м.н.

margosoloshenko@mail.ruhttps://orcid.org/0000-0002-6522-53109095-2169KondratovaSvetlana E.КондратоваСветлана Эдуардовна
Russian Federation
svetlana26.03@mail.ruhttps://orcid.org/0000-0002-5366-894X6471-9838AbashidzeEka A.АбашидзеЭка Амирановна
Russian Federation

MD, PhD

к.м.н.

2803abashidze@mail.ruhttps://orcid.org/0000-0001-7834-213X9754-3642RevunenkovGrigory V.РевуненковГригорий Валериевич
Russian Federation

MD, PhD

к.м.н.

rgv07@mail.ruhttps://orcid.org/0000-0001-6000-54182581-8021KomarovaElena V.КомароваЕлена Владимировна
Russian Federation

MD, PhD

д.м.н.

dr.klv@rambler.ruhttps://orcid.org/0000-0002-4669-95104865-4688IvardavaMarika I.ИвардаваМарика Индикоевна
Russian Federation

MD, PhD

к.м.н.

makussa@mail.ruhttps://orcid.org/0000-0002-4453-84304456-1297DrapkinaOksana M.ДрапкинаОксана Михайловна
Russian Federation

MD, PhD, Professor, Academician of the RAS

д.м.н., профессор, академик РАН

ODrapkina@gnicpm.ruhttps://orcid.org/0000-0002-8984-90563115-0515ShepelRuslan N.ШепельРуслан Николаевич
Russian Federation

MD, PhD

к.м.н.

r.n.shepel@mail.ruhttps://orcid.org/0000-0002-6032-62866906-6680MezhidovKazbek S.МежидовКазбек Султанович
Russian Federation

MD, PhD

к.м.н.

kmezhidov@mail.ruhttps://orcid.org/0000-0002-2209-75311312-2147Namazova-BaranovaLeyla S.Намазова-БарановаЛейла Сеймуровна
Russian Federation

MD, PhD, Professor, Academician of the RAS

д.м.н., профессор, академик РАН

leyla.s.namazova@gmail.comResearch Institute of Pediatrics and Children’s Health in Petrovsky National Research Centre of SurgeryНИИ педиатрии и охраны здоровья детей НКЦ № 2 РНЦХ им. акад. Б.В. ПетровскогоPirogov Russian National Research Medical University (Pirogov Medical University)Российский национальный исследовательский медицинский университет имени Н.И. ПироговаNational Medical Research Center for Therapy and Preventive MedicineНациональный медицинский исследовательский центр терапии и профилактической медицины221220237854084302706202321092023Copyright ©; 2024, "Paediatrician" Publishers LLCCopyright ©; 2024, Издательство "Педиатръ"2024"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/about/submissionshttps://vestnikramn.spr-journal.ru/jour/article/view/14392

Background. One of the four important components of the formation of cognitive functions is somatic health. But to date, there are no population studies that consider the relationship with cognitive functions and school performance of a large range of somatic factors, which allows us to compare the strength of their hypothetical contribution to cognitive functioning with each other. This study is the second part of a population-based study, the first part of which is presented in the previous publication "A Single-Stage Population-Based Study of the Prevalence of Mild Cognitive Impairment in Children of Secondary School Age". Aims — to determine the main patterns in the relationship between cognitive-academic and somatic factors in a cohort of Russian children, 5th grade students at school. Methods. In Russian schoolchildren of the 5th grades of municipalities representing cities of all federal districts of the Russian Federation, the links with integrative cognitive success, the number of subtests performed at the level of mild cognitive impairment, the results of individual cognitive subtests, academic performance and the leading hand factor were analyzed — the following somatic factors: the presence of skin pathology, bronchial asthma, orthopedic, ophthalmological disorders, visual acuity, body mass index, parameters of the study of the function of external respiration, electrocardiography, ultrasound examination of the thyroid gland, laboratory blood tests. Results. The results of the survey of 1036 participants, 51% of them girls, were admitted to the analysis. It has been established that iron content is directly related to integrative cognitive success and school performance, the relationship is especially strong between subgroups of iron content above and below 26.4 mmol/l. Clinical levels of erythrocytes are more strongly associated with integrative cognitive success and individual cognitive functions than other factors: in erythropenia cognitive parameters are worse. The presence of thyroid cysts directly correlates with some of the worst parameters of cognitive activity. High body mass index and low hemoglobin are associated with poorer academic performance. Conclusions. The results of the study for the first time on a cohort of Russian schoolchildren showed a connection with cognitive activity and school performance of a number of somatic factors, including iron content, which requires further in-depth study.

Обоснование. Одной из четырех важных составляющих формирования когнитивных функций является соматическое здоровье. Однако в настоящее время отсутствуют популяционные исследования связей когнитивных функций, школьной успеваемости с большим спектром соматических факторов, позволяющие сравнить силу их гипотетического вклада в когнитивное функционирование между собой. Данное исследование является вторым этапом популяционного исследования, результаты первого представлены в предыдущей публикации «Одномоментное популяционное исследование распространенности легких когнитивных нарушений у детей среднего школьного возраста». Цель исследования — определить основные закономерности в связях между когнитивно-академическими и соматическими факторами в когорте российских детей — учащихся 5-х классов. Методы. У российских школьников 5-х классов муниципальных образований, представлявших города всех федеральных округов Российской Федерации, проанализированы связи с интегративной когнитивной успешностью, количеством субтестов, выполненных на уровне легких когнитивных нарушений, результатами выполнения отдельных когнитивных субтестов, академической успеваемостью и фактором ведущей руки следующих соматических факторов: наличие патологии кожи, бронхиальной астмы, ортопедических, офтальмологических нарушений, острота зрения, индекс массы тела (ИМТ), нарушения функции внешнего дыхания (ФВД), электрокардиография (ЭКГ), ультразвуковое исследование щитовидной железы, лабораторные анализы крови. Результаты. В анализ включены результаты обследования 1036 участников, из них 51% девочек. Установлено, что содержание железа напрямую связано с интегративной когнитивной успешностью и школьной успеваемостью, особенно сильно связь проявляется между подгруппами участников, выделенных по уровню содержания железа выше и ниже 26,45 мкмоль/л. Клинические уровни эритроцитов сильнее других факторов связаны с интегративной когнитивной успешностью и отдельными когнитивными функциями: при эритропениях когнитивные параметры хуже. Наличие кист щитовидной железы прямо коррелирует с некоторыми худшими параметрами когнитивной деятельности. Высокий ИМТ и низкое содержание гемоглобина связаны с худшей успеваемостью. Заключение. Результаты исследования на когорте российских школьников показали связь с когнитивной деятельностью и школьной успеваемостью ряда соматических факторов, включая содержание железа, что требует дальнейшего углубленного изучения.

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