Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC14110.15690/vramn.v68i10.790SHORT MESSAGESКРАТКИЕ СООБЩЕНИЯELECTROPHYSIOLOGICAL MARKERS OF MIDDLE CEREBRAL ARTERY BLOOD FLOW VELOCITY IN HEALTHY SUBJECTSЭЛЕКТРОФИЗИОЛОГИЧЕСКИЕ КОРРЕЛЯТЫ СКОРОСТИ ДВИЖЕНИЯ КРОВИ ПО СРЕДНЕЙ МОЗГОВОЙ АРТЕРИИ ЗДОРОВОГО ЧЕЛОВЕКАFokinV. F.ФокинВ. Ф.
Russian Federation

PhD, professor, Head of the development brain physiology department of the Federal State Budgetary Institution “Scientific Center of Neurology” of RAMS. Address: 80, Volokolamskoye Route, Moscow, 125367, tel.: (495) 917-07-65

fvf@mail.ruPonomarevaN. V.ПономареваН. В.
Russian Federation

PhD, leading research scientist, Head of the genetic and physiological mechanisms of brain aging group of the Federal State Budgetary Institution “Scientific Center of Neurology” of RAMS. Address: 80, Volokolamskoye Route, Moscow, 125367, tel.: (495) 917-07-65

ponomare@yandex.ruKuntsevichG. I.КунцевичГ. И.
Russian Federation

PhD, professor, Head of the ultrasonic investigations laboratory of the Federal State Budgetary Institution “Scientific Center of Neurology” of RAMS. Address: 80, Volokolamskoye Route, Moscow, 125367, tel.: (495) 490-24-07

doctorkunsevich@mail.ruResearch Centre of Neurology RAMS, Moscow, Russian FederationНаучный центр неврологии РАМН, Москва, Российская Федерация101020136810Vestnik Rossiiskoi akademii medetsinskikh nauk / Annals of the Russian academy of medical sciencesВестник Российской академии медицинских наук576007082015Copyright ©; 1970, "Paediatrician" Publishers LLCCopyright ©; 1970, Издательство "Педиатръ"1970"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/article/view/141

Aim: to determine electrophysiological markers of middle cerebral artery blood flow velocity (BFV). Patients and methods: transcranial Doppler registration of middle cerebral artery BFV and direct current (DC) potentials recording from surface of head were performed in 30 healthy volunteers. Analysis of correlation between the BFV and DC potentials was used. Results: significant correlation between BFV and DC potential characteristics was observed. The highest correlation was found between BFV in middle cerebral artery and the difference of DC potentials between central and temporal areas of head (r =0,55; p =0,003). These areas coincide with the location of middle cerebral artery and the correlation observed may be connected with streaming potential generated by the blood flow in middle cerebral artery. If electrode placement did not coincide with blood current, DC potentials and BFV were not correlated. Conclusions: it is assumed that electrical field created BFV in middle cerebral artery may contribute to the generation of DC potentials registered from the head.

Цель исследования: установить электрофизиологические корреляты скорости кровотока по средней мозговой артерии. Пациенты и методы: у 30 здоровых добровольцах методами допплерографии регистрировали систолическую линейную скорость кровотока по средней мозговой артерии и уровень постоянного потенциала (УПП) между электродами, расположенными вдоль хода основных ветвей средней мозговой артерии. Результаты: показана достоверная корреляция скорости кровотока по средней мозговой артерии здоровых людей с распределением УПП. Наибольшую взаимосвязь между скоростью кровотока в средней мозговой артерии с разностью УПП наблюдали при расположении регистрирующих электродов по ходу восходящих ветвей средней мозговой артерии (r =0,55; p =0,003). Биполярные регистрации УПП, не совпадающие с ориентацией восходящих ветвей средней мозговой артерии, в целом хуже коррелируют с линейной скоростью кровотока в средней мозговой артерии. Выводы: предполагается, что движение крови по крупным сосудам головного мозга создает электрическое поле, которое при высокой скорости кровотока может быть зарегистрировано с поверхности головы.

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