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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Annals of the Russian academy of medical sciences</journal-id><journal-title-group><journal-title xml:lang="en">Annals of the Russian academy of medical sciences</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российской академии медицинских наук</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-6047</issn><issn publication-format="electronic">2414-3545</issn><publisher><publisher-name xml:lang="en">"Paediatrician" Publishers LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">13996</article-id><article-id pub-id-type="doi">10.15690/vramn13996</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>PEDIATRICS: CURRENT ISSUES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>АКТУАЛЬНЫЕ ВОПРОСЫ ПЕДИАТРИИ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Electrical Instability of the Myocardium in Children and Adolescents</article-title><trans-title-group xml:lang="ru"><trans-title>Электрическая нестабильность миокарда у детей и подростков</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2290-0013</contrib-id><contrib-id contrib-id-type="spin">2024-5807</contrib-id><name-alternatives><name xml:lang="en"><surname>Balykova</surname><given-names>Larisa A.</given-names></name><name xml:lang="ru"><surname>Балыкова</surname><given-names>Лариса Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor, Corresponding Member of the RAS</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор, член-корреспондент РАН</p></bio><email>larisabalykova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9049-5662</contrib-id><contrib-id contrib-id-type="spin">2141-2903</contrib-id><name-alternatives><name xml:lang="en"><surname>Shirmankina</surname><given-names>Marina V.</given-names></name><name xml:lang="ru"><surname>Ширманкина</surname><given-names>Марина Васильевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Clinical Resident</p></bio><bio xml:lang="ru"><p>ординатор</p></bio><email>shirmankina99@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0087-4421</contrib-id><contrib-id contrib-id-type="spin">9931-6767</contrib-id><name-alternatives><name xml:lang="en"><surname>Ivyanskiy</surname><given-names>Stanislav A.</given-names></name><name xml:lang="ru"><surname>Ивянский</surname><given-names>Станислав Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук</p></bio><email>stivdoctor@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3990-9353</contrib-id><contrib-id contrib-id-type="spin">6033-5816</contrib-id><name-alternatives><name xml:lang="en"><surname>Krasnopolskaya</surname><given-names>Anna V.</given-names></name><name xml:lang="ru"><surname>Краснопольская</surname><given-names>Анна Валерьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук</p></bio><email>abalykova@gmail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2121-8346</contrib-id><contrib-id contrib-id-type="spin">1070-6203</contrib-id><name-alternatives><name xml:lang="en"><surname>Vladimirov</surname><given-names>Denis O.</given-names></name><name xml:lang="ru"><surname>Владимиров</surname><given-names>Денис Олегович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Post-Graduate Student</p></bio><bio xml:lang="ru"><p>аспирант</p></bio><email>d.o.vladimirov@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4401-8395</contrib-id><contrib-id contrib-id-type="spin">7409-3568</contrib-id><name-alternatives><name xml:lang="en"><surname>Shablinova</surname><given-names>Tatyana S.</given-names></name><name xml:lang="ru"><surname>Шаблинова</surname><given-names>Татьяна Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Post-Graduate Student</p></bio><bio xml:lang="ru"><p>аспирант</p></bio><email>Doc.Parshina@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1193-3178</contrib-id><contrib-id contrib-id-type="spin">5039-9934</contrib-id><name-alternatives><name xml:lang="en"><surname>Tyagusheva</surname><given-names>Evgenia N.</given-names></name><name xml:lang="ru"><surname>Тягушева</surname><given-names>Евгения Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Student</p></bio><bio xml:lang="ru"><p>студент</p></bio><email>evgenia.tyagusheva@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Research Ogarev Mordovia State University</institution></aff><aff><institution xml:lang="ru">Национальный исследовательский Мордовский государственный университет им. Н.П. Огарева</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-01-15" publication-format="electronic"><day>15</day><month>01</month><year>2024</year></pub-date><volume>79</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>52</fpage><lpage>59</lpage><history><date date-type="received" iso-8601-date="2023-06-19"><day>19</day><month>06</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-12-01"><day>01</day><month>12</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, "Paediatrician" Publishers LLC</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Издательство "Педиатръ"</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">"Paediatrician" Publishers LLC</copyright-holder><copyright-holder xml:lang="ru">Издательство "Педиатръ"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-03-01"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnikramn.spr-journal.ru/jour/about/submissions</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnikramn.spr-journal.ru/jour/article/view/13996">https://vestnikramn.spr-journal.ru/jour/article/view/13996</self-uri><abstract xml:lang="en"><p>Currently, there is no doubt that the problem of electrical instability of the myocardium in pediatric cardiology is relevant. The determination of various indicators of electrical instability of the myocardium, which are predictors of life-threatening rhythm disorders and sudden cardiac death, presents an underdeveloped task not only for functional diagnostics specialists, but also for pediatricians, neonatologists, pediatric cardiologists and doctors of other specialties. Non-invasive research methods such as electrocardiography (ECG), Holter ECG monitoring (HM ECG), available in almost all pediatric treatment and prevention institutions, are quite informative in terms of detecting electrophysiological heterogeneity of the myocardium as a predictor of sudden cardiac death, which is especially important in children at risk, as well as young athletes. Thus, the determination of indicators of electrical instability of the myocardium is of great interest, it is a promising direction in modern clinical practice, allowing to predict the risk of developing fatal arrhythmias in children and adolescents.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время не вызывает сомнения актуальность проблемы электрической нестабильности миокарда в детской кардиологии. Определение различных показателей электрической нестабильности миокарда, являющихся предикторами жизнеугрожающих нарушений ритма и внезапной сердечной смерти, представляет недостаточно разработанную задачу не только для специалистов по функциональной диагностике, но и педиатров, неонатологов, детских кардиологов и врачей других специальностей. Такие неинвазивые методы исследования, как электрокардиография (ЭКГ), холтеровское мониторирование ЭКГ, доступные практически во всех детских лечебно-профилактических учреждениях, довольно информативны в плане выявления электрофизиологической неоднородности миокарда как предиктора внезапной сердечной смерти, что особенно важно у детей из групп риска, а также юных спортсменов. Таким образом, определение показателей электрической нестабильности миокарда представляет большой интерес, является перспективным направлением в современной клинической практике, позволяющим прогнозировать риск развития фатальных аритмий у детей и подростков.</p></trans-abstract><kwd-group xml:lang="en"><kwd>rhythm disturbances</kwd><kwd>children</kwd><kwd>electrocardiography</kwd><kwd>QT interval</kwd><kwd>rhythm variability</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>электрическая нестабильность миокарда</kwd><kwd>дети</kwd><kwd>ЭКГ</kwd><kwd>QT-интервал</kwd><kwd>вариабельность ритма</kwd></kwd-group><funding-group><award-group><funding-source><institution-wrap><institution xml:lang="ru">Национальный исследовательский Мордовский государственный университет им. Н.П. Огарева</institution></institution-wrap><institution-wrap><institution xml:lang="en">National Research Ogarev Mordovia State University</institution></institution-wrap></funding-source></award-group></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Münkler P, Klatt N, Scherschel K, et al. Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle. Europace. 2023;25(2):688–697. doi: https://doi.org/10.1093/europace/euac126</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Vorobiev AP, Vaykhanskaya TG, Melnikova OP, et al. Digital Electrocardiographic System for Assessing Myocardial Electrical Instability: Principles and Applications. Sovrem Tekhnologii Med. 2021;12(6):15–19. doi: https://doi.org/10.17691/stm2020.12.6.02</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Karpuz D, Hallıoğlu O, Yılmaz DÇ. 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