Annals of the Russian academy of medical sciencesAnnals of the Russian academy of medical sciencesВестник Российской академии медицинских наук0869-60472414-3545"Paediatrician" Publishers LLC124310.15690/vramn1243РATHOPHYSIOLOGY: CURRENT ISSUESАКТУАЛЬНЫЕ ВОПРОСЫ ПАТОФИЗИОЛОГИИResearch ArticleOsteosarcopenia: pathogenesis, diagnosis and therapeutic approachesОстеосаркопения: патогенез, диагностика и возможности терапииhttps://orcid.org/0000-0003-1413-15494380-5447GrebennikovaTatiana A.ГребенниковаТатьяна Алексеевна
Russian Federation

MD, PhD

к.м.н.

Grebennikova@hotmail.comhttps://orcid.org/0000-0001-9074-22917234-2499TsorievTimur TЦориевТимур Тамерланович
Russian Federation

MD

к.м.н.

timur.tsoriev@gmail.comhttps://orcid.org/0000-0003-2884-1349VorobevaJuliya RВоробьеваЮлия Романовна
Russian Federation

Resident

клинический ординатор

ju.vorobeva.ru@gmail.comhttps://orcid.org/0000-0002-6674-64414746-7173BelayaZhanna EБелаяЖанна Евгеньевна
Russian Federation

MD, PhD

д.м.н.

jannabelaya@gmail.comThe National Medical Research Center for EndocrinologyНациональный медицинский исследовательский центр эндокринологии Минздрава России310820207532402491211201902062020Copyright ©; 2020, "Paediatrician" Publishers LLCCopyright ©; 2020, Издательство "Педиатръ"2020"Paediatrician" Publishers LLCИздательство "Педиатръ"https://vestnikramn.spr-journal.ru/jour/about/submissionshttps://vestnikramn.spr-journal.ru/jour/article/view/1243

Osteosarcopenia was identified as a separate syndrome in 2009, and is defined as a combination of sarcopenia and osteopenia/osteoporosis. Osteosarcopenia develops mainly in old age, leads to a decrease in quality of life, an increased risk of falls and low-traumatic fractures. Patients with osteosarcopenia have worse indicators of physical functions, compared with people suffering from only one of the components of the syndrome. An important role in the osteosarcopenia prevention is played by the lifestyle of patients, Adherence to diet with the consumption of adequate amount of protein, physical activity and preventive prescription of calcium and vitamin D are important for osteosarcopenia prevention. The article summarizes data on the prevalence, pathogenesis and risk factors of osteosarcopenia, provides diagnostic criteria for the disease and discusses therapeutic approaches.

Остеосаркопения, выделенная как отдельный синдром относительно недавно, в 2009 г., представляет собой сочетание саркопении и остеопении или остеопороза. Остеосаркопения развивается преимущественно в пожилом возрасте, приводит к снижению качества жизни пациентов, повышению риска падений и патологических переломов у ослабленных пациентов. При этом пациенты с остеосаркопенией имеют худшие показатели физических функций по сравнению с лицами, страдающими лишь одним из компонентов синдрома. Важную роль в профилактике остеосаркопении играют образ жизни пациентов, соблюдение режима питания с потреблением адекватного количества белка, расширение физической активности, превентивное назначение препаратов кальция и витамина D. В статье суммированы данные о распространенности, патогенезе, факторах риска остеосаркопении, приведены диагностические критерии заболевания и подробно рассмотрены направления медикаментозной терапии.

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