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THE STRUCTURE OF PHARMACOTHERAPY OF ARTERIAL HYPERTENSION AND ADHERENCE IN YOUNG PATIENTS
- Authors: Tuleutayeva R.Y.1, Musina A.Y.1, Cebotarenko N.A.2, Makhatova A.R.1
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Affiliations:
- Semey State Medical University
- Coalition on Rational Drug Use, World Health Organization
- Issue: Vol 72, No 6 (2017)
- Pages: 428-434
- Section: CARDIOLOGY AND CARDIOVASCULAR SURGERY: CURRENT ISSUES
- URL: https://vestnikramn.spr-journal.ru/jour/article/view/860
- DOI: https://doi.org/10.15690/vramn860
- ID: 860
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Abstract
Aim: To determine the indicators of adherence to drug therapy in young patients with arterial hypertension (АН) and the correlation between the indicators and therapy management.
Materials and methods: The study enrolled 514 patients aged 25 to 45 years diagnosed with essential hypertension. We studied the structure of antihypertensive pharmacotherapy and adherence to treatment using the Moriski−Green test and the original questionnaire. The patients were distributed depending on the degree of blood pressure increase, administered treatment, age, economic factor, and drug source.
Results: The adherence level by Moriski−Green test was 36.8%; according to the original questionnaire: high adherence level was 38.3%, incomplete adherence ― 33.7%, and poor adherence ― 28.0%. The monotherapy with ACE inhibitors predominated in the majority of cases; the fixed combinations were more typical for the treatment of the stage II AH, drug combinations ― for stage III AH. The highest therapy adherence was registered in patients with stage III AH receiving treatment with combinations of drugs in a single dosage form. The life quality of respondents and the drug source did not influence the adherence significantly.
Conclusion: In young patients with arterial hypertension, some features of treatment structure determine the therapy adherence.About the authors
R. Ye. Tuleutayeva
Semey State Medical University
Email: raikhan65@mail.ru
ORCID iD: 0000-0002-0462-5230
Semey Kazakhstan
A. Ye. Musina
Semey State Medical University
Author for correspondence.
Email: musina_med@mail.ru
ORCID iD: 0000-0002-0114-5397
Semey Kazakhstan
N. A. Cebotarenko
Coalition on Rational Drug Use, World Health Organization
Email: corsumnews@gmail.com
ORCID iD: 0000-0003-4619-4421
Chisinau
Moldova, Republic ofA. R. Makhatova
Semey State Medical University
Email: asem_ram@mail.ru
ORCID iD: 0000-0003-4127-7279
Semey Kazakhstan
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