MOLECULAR MECHANISMS OF DEVELOPMENT OF CEREBRAL TOLERANCE TO ISCHEMIA. PART 1

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Abstract

In the first part of this review molecular mechanisms of ischemic tolerance emerging as a result of preconditioning of the brain are discussed. Data on inductors, sensors, transducers and effectors of early and delayed ischemic tolerance are presented.

About the authors

E. V. Shlyakhto

Saint- Petersburg State Medical Pavlov’s University, Saint-Petersburg
Saint-Petersburg, Almazov Federal Heart, Blood and Endocrinology Centre

Author for correspondence.
Email: shlyakhto@almazovcentre.ru
доктор медицинских наук, профессор, академик РАМН, директор ФГБУ «Федеральный центр сердца, крови и эндокринологии им. В.А. Алмазова» Минздравсоцразвития России, заведующий кафедрой факультетской терапии СПбГМУ им. акад. И.П. Павлова Адрес: 197341, Санкт-Петербург, ул. Аккуратова, д. 2 Тел.: (812) 702-37-00 Russian Federation

E. P. Barantsevich

Saint- Petersburg State Medical Pavlov’s University, Saint-Petersburg
Saint-Petersburg, Almazov Federal Heart, Blood and Endocrinology Centre

Email: profossrerb@yandex.ru
доктор медицинских наук, профессор, заведующий кафедрой неврологии и мануальной медицины ФПО СПбГМУ им. акад. И.П. Павлова, заведующий НИО ангионеврологии ФГБУ «Федеральный центр сердца, крови и эндокринологии им. В.А. Алмазова» Минздравсоцразвития России Адрес: 197022, Санкт-Петербург, ул. Л. Толстого, д. 6/8 Тел/факс: 8 (812) 233-45-26 Russian Federation

N. S. Shcherbak

Saint- Petersburg State Medical Pavlov’s University, Saint-Petersburg
Saint-Petersburg, Almazov Federal Heart, Blood and Endocrinology Centre

Email: shcherbakns@yandex.ru
кандидат биологических наук, старший научный сотрудник лаборатории неотложной кардиологии Института сердечно-сосудистых заболеваний СПбГМУ им. акад. И.П. Павлова, ведущий научный сотрудник лаборатории нанотехнологий ФГБУ «Федеральный центр сердца, крови и эндокринологии им. В.А. Алмазова» Минздравсоцразвития России Адрес: 197341, Санкт-Петербург, ул. Аккуратова, д. 2 Тел.: (812) 702-37-00 Russian Federation

M. M. Galagudza

Saint- Petersburg State Medical Pavlov’s University, Saint-Petersburg
Saint-Petersburg, Almazov Federal Heart, Blood and Endocrinology Centre

Email: galagoudza@mail.ru
доктор медицинских наук, руководитель Института экспериментальной медицины ФГБУ «Федеральный центр сердца, крови и эндокринологии им. В.А. Алмазова» Минздравсоцразвития России, профессор кафедры патофизиологии СПбГМУ им. акад. И.П. Павлова Адрес: 197022, Санкт-Петербург, ул. Л. Толстого, д. 6/8 Russian Federation

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