IgE-RESPONSE AFTER ADMINISTRATION OF PANDEMIC VACCINE STRAIN A/CALIFORNIA/7/2009 (H1N1) v

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Abstract

Changes in total and allergy-specific IgE (IgE-antibodies) in 70 healthy volunteers vaccinated with influenza vaccine subunit strain A/California/7/2009/(H1N1). Safety of this vaccine was shown. Repeated second dose administration is not accompanied by increase in IgE-antibodies to egg components. Vaccine injection results in decrease of total IgE in patients with elevated IgE at baseline.

 

About the authors

M. P. Kostinov

Russian Academy of Medical Sciences (RAMS) Mechnicov Reseach Institute of Vaccines and Sera

Author for correspondence.
Email: vaccine@bk.ru
доктор медицинских наук, профессор, Заслуженный деятель науки РФ, заведующий лабораторией вакцинопрофилактики и иммунотерапии аллергических заболеваний НИИВС им. И.И. Мечникова РАМН Адрес: 105064, Москва, Малый Казенный пер., д. 5-а Тел., факс: (495) 917-41-49 Russian Federation

O. A. Terkacheva

Russian Academy of Medical Sciences (RAMS) Mechnicov Reseach Institute of Vaccines and Sera

Email: lylygin@rambler.ru
аспирант НИИВС им. И.И. Мечникова РАМН Адрес: 105064, Москва, Малый Казенный пер., д. 5-а Russian Federation

S. N. Zhirova

Russian Academy of Medical Sciences (RAMS) Mechnicov Reseach Institute of Vaccines and Sera

Email: svaccina@mail.ru
ведущий научный сотрудник НИИВС им. И.И. Мечникова РАМН Адрес: 105064, Москва, Малый Казенный пер., д. 5-а Тел., факс: (495) 917-41-49 Russian Federation

A. P. Cherdanchev

Ulyanovsk State University

Email: niti@ulsu.ru
научный сотрудник кафедры педиатрии Ульяновского государственного университета Адрес: 432700, Ульяновск, ул. Л. Толстого, д. 42 Тел.: (8422) 41-20-88; факс: (8422) 41-23-40 Russian Federation

M. K. Erofeeva

Research Institute of Influenza, St. Petersburg

Email: office@influenza.spb.ru
старший научный сотрудник НИИ гриппа МЗиСР РФ Адрес: 197376, Санкт-Петербург, ул. проф. Попова, д. 15/17 Тел.: (812) 234-62-00; факс: (812) 234-59-00 Russian Federation

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