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The formation of microbial biomembranes complicates clinical course of infectious diseases. The review deals with the problem of interaction between immune system and specific components of microbial biofilms. The immune mechanisms which may destroy biomembranes and damage biomembrane-associated microorganisms are analyzed. The vulnerable spots of immune defense against microbal biomembranes are described. This review also issues future prospects of immune-based control of microbal biomembrane processes.


About the authors

I. V. Chebotar'

Nizhny Novgorod State Medical Academy

Author for correspondence.
Candidate of Medical Sciences, Associate Professor, Chair of Microbiology and Immunology, State Education Institute Nizhniy Novgorod State Medical Academy, Ministry of Health, Russian Federation Address: 603005, Nizhniy Novgorod, Minin and Pozharskiy square, 10/1; Tel.: (831) 439-09-43 Russian Federation


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